rbp 中文意思是什麼
rbp
解釋
輻射誘發臂叢病-
Raised bed planting ( rbp ) can get higher grain yield and water use efficiency than flat planting ( fp )
壟作小麥冠層為波浪狀,有利於提高小麥的籽粒產量和水分利用效率。 -
Notch interaction with its ligands induces the cleavage of its intracellular domain ( ic ), and the notch ic translocates to the nucleus and binds to rbp - j, the mammalian homolog of su ( h ), to transactivate transcription of target genes such as e ( spl ) ( enhancer of split ), hesl ( hairy and enhancer of split ) and hes5 four notch receptors and their ligands are differentially and redundantly expressed in a variety of vertebrate tissues
它通過其識別序列( cogtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。在沒有n 。 tch胞內段的情況下, rbpj可與包含sm盯( silencingmediatorforretlnoldandthyroidhormonereceptor )和組蛋白去乙酞化酶的轉錄輔助抑制復合物結合,當notch信號被激活時; rbpj可與n 。 -
The two single - pass transmembrane proteins, delta and serrate, have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway. rbp - j, the mammalian homolog of su ( h ), recognizes the core sequence ( c / tgtgggaa ) of dna
Rbp - j是果蠅促神經發生基因su ( h ) ( suppressorofhairless )在哺乳動物的同源物,它通過其識別序列( c tgtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。 -
Mint ( msx2 - interacting nuclear target protein ) can interact with rbp - j and msx2 ( the murine homologue of drosophlia muscle - segment homeobox ), and represses their transcription activation activity
進一步的研究表明mint可以與n成ch受體的胞內段競爭結合rbp j , n而抑制rbp刁的轉錄激活作用。 -
The targeted disruption of mouse rbp - j revealed that homozygous null mutants die before 10. 5 days postcoitum ( dpc ) with various abnormalities, including growth retardation and defects in the central nervous system and somites
5天死亡,同時伴隨一系列異常,包括神經發育過度及體節發育的缺陷,說明rbp - j在哺乳動物胚胎發育中發揮著重要作用。 -
The targeted disruption of mouse rbp - j revealed that homozygous null mutants die before 10. 5 days postcoitum ( dpc ) with various abnormalities, including growth retardation and defects in the central nervous system and somites. in order to assess the function of rbp - j, a yeast two - hybrid screening using rbp - j as a bait protein was performed and a nuclear matrix protein, mint was isolated
Sdpc胚胎和人的hela細胞cdna文庫中篩選到一個可以與rbp斗相互作用的新蛋白ram7 ,后發laram7與mmt ( msxz inter肌tingnucleartargetprotein )為同一蛋白。 -
So rbp is regarded as sensitive biomarker for the clinical diagnose of these diseases. it can also reveal the early change of nutrition state of protein
因此,臨床上將其作為診斷某些疾病的輔助指標,同時也用來評價蛋白質營養狀況的早期變化。 -
Based on rbf neural network and perceptron neural network, a four - layer feed - forward neural network named radial basis perceptron ( rbp ) network is presented
基於rbf網路和感知器( perceptron )網路建立一四層前饋神經網路?徑向基感知器( radialbasisperceptron , rbp )網路。 -
And it easily degraded. so it ' s difficult to isolate and purify rbp from human and animal plasma and urine of kidney patients. in order to study the structure - function of rbp, we produced rbp from escherichia coli by constructing engineering strain which can express rbp
維生素a結合蛋白在體內的含量很低,容易降解,從人或動物的血漿以及腎病綜合征患者的尿中分離提取有活性的維生素a結合蛋白十分困難,極大的限制了對其結構、功能及代謝機制的研究,而且該蛋白價格昂貴,也不利於臨床的廣泛應用。 -
On the other hand, the rbp - j protein is ubiquitously expressed, and commonly activated by all of four notch receptors
H受體和不同的配體分別表達子哺乳動物不同的細胞,而rbp卻是普遍表達的,所以rbp j是n 。 -
To satisfy the need for cell differentiation, vision maintenance, reproduction and individual maturity, vitamin a is transported to target cell in a highly specific and regulated manner by combination with rbp and transthyretin. the fluctuation of rbp in blood circulation or urine could be observed due to some diseases
維生素a結合蛋白與維生素a及前白蛋白以1 : 1 : 1的比例結合形成復合物后,共同將維生素a從肝臟運送到靶組織以滿足機體生長發育、視覺維護以及細胞分化等生命活動需要。 -
Kyot2 lacked two lim domains from the c terminus and had a frameshift in the last exon, creating the rbp - j - binding region in the c terminus. kyotl had a negligible level of interaction with rbp - j. the binding site of kyot2 on rbp - j overlaps those of ramic and kyot2 repressed the rbp - j mediated transcriptional activation by ramic by competing with them for binding to rbp - j
在肌肉母細胞系czc12內過表達kyoth時可阻斷轉錄激活物notch胞內區或ebnaz對rbp依賴性啟動子的轉錄激活作用,這種阻斷作用呈劑量依賴性,提示kyoth可與notch胞內區或ebnaz競爭rbp j上的結合位點,從而抑制二者的轉錄激活活性 -
Through these experiments we realized cloning of the gene of rbp and its expression in procaryotic cell
Colidh5中獲得了有效表達,為以後的研究工作奠定了基礎。 -
On the bases of designing a primer pair, we obtained the coding domain sequence of rbp by pcr from cdna library. then the gene was cloned into pgem - t vector, the dna sequencing showed that the cloned gene was in agreement with the reported sequence. then the tageted gene of rbp was further subcloned into a procaryotic expression vector pbv220 and constructed recombinant plasmids was named pbv220 - rbp. in order to expresse rbp in procaryotic cell efficiently, the recombinant plasmids was introduced into e. colidhs a straints. expression of rbp was induced by temperature induction
本實驗在合成該蛋白基因上下游引物的基礎上,利用pcr技術,從人睪丸cdna庫中釣取目的基因,並克隆于pgem - t載體中,經序列測定證明與文獻報道基本一致,再將目的基因從重組克隆質粒中亞克隆于pbv220原核表達載體中,轉化宿主菌,經溫度誘導后,進行sds - page電泳分析,發現在約21kd位置上出現了一條明顯的蛋白帶,與預期相符。 -
Using yeast two - hybrid system honjo ' s group in kyoto university isolated a novel protein, kyot, which physically interacts with rbp - j. differential splicing gives rise to three transcripts of the kyot gene, kyotl, kyot2 and kyots. kyot2, but not kyotl negatively regulates transcription by association with rbp - j
為進一步探討rbp - j的功能,日本京都大學的honjo研究組利用酵母雙雜交系統篩選到一個可以與rbp - j相互作用的新蛋白kyot , kyot蛋白有三種不同的剪切體: kyot1 , kyot2和kyot3 ,其中kyot2可以與rbp - j相互作用抑制其轉錄活性。 -
Rbp - j directly interacts with ramic to activate transcription of downstream target genes that prevent cell differentiation. thus, rbp - j is a critical effector molecule in notch signaling pathway
5dpc胚胎和人的hela細胞cdna文庫中篩選到一個可以與rbp - j第四軍醫大學博士學位論文相互作用的新蛋白kyot -
The width parameter crof centers is self - adjustable according to the information included in the training samples. the validity of this network is illustrated using an example taken from component analysis of cao - al2o3 - sio2 system. simulation shows that rbp network can predict the components of civil building materials successfully and gets good generalization ability
以cao - al _ 2o _ 3 - sio _ 2系統為例,對材料成分分析領域的模擬結果表明,該網路可成功地包含材料成分的構成信息,實現精確分類,並具有較高的泛化能力。 -
To discuss whether there is later - comer advantage is n ' t important, the most important is to find a way to win later - comer advantage in the condition of globalization. in the view of rbp, the growth of chinese companies can be separated three stages : the first stage is to accumulate resource, consisting of obtaining tangible and intangible asset
本文認為,后發有優勢,也有劣勢,問題的關鍵不在於存不存在後發優勢,而是在總結我國企業四十多年來在引進技術基礎上開展二次創新經驗的基礎上,探索如何在新的環境下獲取后發優勢的有效途徑。 -
In order to assess the function of rbp - j, a yeast two - hybrid screening using rbp - j as a bait protein was employed and a lim protein, kyot, was isolated
Kyot是一種lim結構域蛋白,有兩種亞型kyoti和kyotz ,在染色體上由同一基因編碼 -
These results suggest that kyot plays an important role in the development of testis and spermatogenesis. 2 we performed yeast two - hybrid screening of a cdna library from human lymph nodes using kyot2 as a bait protein. 42 clones were gotten after 5xl06 were screened by four kinds of nutrition limitation and p - galactosidase assay, 22 clones were got after restriction of positive clones, at last, 13 genes were got by sequence assay including rbp - j known as the interacting protein with kyot before and two novel genes
對此22個克隆進行序列分析,共獲得13種基因,其中包括已知的kyot相互作用蛋白rbpj和兩個未知基因,也包括在哺乳動物睪丸中特異3第四軍醫大學博士學位論文性表達的蛋白piasi ,同時還篩到了具有可與lm結構鞠互作用的pdzdomain分子緊密連接蛋白2和兩種同屬于kg家族的蛋白ringi和polycomb2
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