receptor blockade 中文意思是什麼

receptor blockade 解釋
受體封閉
  • receptor : n. 【生物學】感受器；受體；【化學】接受器；受納體；【電學】感受器；接收器。
  • blockade : n 1 封鎖，堵塞。2 實施封鎖的武力〈部隊〉。3 〈美國〉（交通的）阻斷。vt 封，堵塞，封鎖，妨礙，阻止...
  1. Among antihypertensive measures, blockade of the raas by means of ace inhibitors or angiotensin ii receptor antagonists recently emerged as a potentially polyvalent approach, not only for treating hypertension and reducing cardiovascular events, but also to prevent or reduce albuminuria, counteract diabetic nephropathy and lower the occurrence of new type 2 diabetes in individuals at risk

    在抗高血壓藥物治療中，通過用ace抑制劑或血管緊張素受體拮抗劑可阻滯腎素-血管緊張素-醛固酮系統激活，最近其可作為一種潛在多能的治療方法，不僅可治療高血壓和減少心血管事件，也能夠預防或減少蛋白尿，阻止糖尿病性腎病變，並使新糖尿病患者發生風險性降得更低。
  2. Many laboratories have demonstrated that nmda - receptor blockade reduces infarct volume in both lissencephalic and gyrencephalic animal models of transient or permanent focal ischemia

    許多實驗室都證明阻斷了nmda受體能降低短暫或永久性局灶性缺血模型的梗死面積。
  3. Excitotoxicity, associated with stroke and neurodegeneration, is triggered primarily by massive ca2 + influx arising from overactivation of glutamate receptor channels of the n - methyl - d - aspartate ( nmda ) subtype. although approaches to treatment of these disorders with antagonists of nmda receptor ( nr ) have been testified to be effective in animal models, successful therapy in humans was limited by the severe side effects of complete nr blockade for their space window and time window

    已有的nr受體拮抗劑或阻斷劑均為人工合成的小分子藥物，能彌散通過血腦屏障（空間窗過大） ，作用選擇性低，病變腦區及非病變腦區都會受到影響，而且由於神經元可逆性損害的「時間窗」極短，人們難以適時使用有效的神經保護藥物，這些均導致已有的藥物難以進入臨床。
  4. Exogenous angiotensin ii test showed that complete angiotensin receptor blockade was achieed only in the high - dosage groups

    外源性血管緊張素試驗表明，完全的血管緊張素受體封閉是僅僅在高劑量組取得。
  5. Exogenous angiotensin ii test showed that complete angiotensin receptor blockade was achieved only in the high - dosage groups

    外源性血管緊張素試驗表明，完全的血管緊張素受體封閉是僅僅在高劑量組取得。
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