receptor-ligand 中文意思是什麼
receptor-ligand
解釋
受體配基-
Recently, ldl apheresis has been applied in clinic and achieves a satisactory effect. in this dissertation, the tripeptide, serine - aspartic - glutamic acid ( sde ), which existes in the cooh - terminal end of the seven repeats in the ligand binding domain of the ldl receptor and plays an important role in identifying ldl, was synthetized and immobilized onto the polyacrylamide ( paam ) beads as a bionic adsorbent for selective removal of ldl from plasma
本論文以絲氨酰-天冬氨酰-谷氨酸（ sde ）負電性三肽（此三肽廣泛存在於ldl受體配體結合域7個重復序列的羧基末端，對ldl受體特異性識別ldl起著重要作用）作為配體固定到聚丙烯酰胺微球載體上製成仿生性ldl親和吸附劑，考察其對人血漿中ldl及hdl的吸附功效。 -
Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis
首先，用~ （ 35 ） s標記的氨基酸混合物喂養工程菌成功地制備了~ （ 35 ） s標記的擬南芥鈣調素（ ~ （ 35 ） s - cam ） ， ~ （ 35 ） s - cam純度高、放射活度高、 ca ~ （ 2 + ）與egta存在時的電泳行為與未標記cam相同，可作為一種高靈敏性的探針用於進行受體學分析實驗；用擬南芥種子誘導愈傷，通過酶解制備了大量原生質體。 -
Determination of a fine binding site of ligand to fibroblast growth factor receptor
成纖維細胞生長因子受體1配體精細結合位點的確定 -
In order to detect the effect of human sperm mannose - ligand receptor on the fertilization ability, in the study reported here mannose - ligand receptors ( mrs ) were purified from human sperm by modified mannose - agarose gel affinity chromatography coloumn and determined protien concentration by lowry, preincubated zona - free hamster oocytes with four purified mannose - ligand receptor ( pmr ) concentrations before sperm penetration assay ( spa ) to test the pmrs cell biology nature of inhibition to fertilization
本研究用改良后的親和層析法分離純化mr ， lowry法測定其蛋白質濃度，在精子穿透試驗（ spermpenetrationassay ， spa ）模型中定量研究其對精卵融合能力的影響並檢測其細胞生物學活性；以已知濃度的pmr （ purifiedmannose - ligandreceptor ）干預精子半透明帶試驗，觀察用pmr預處理半透明帶對精子與透明帶結合的影響。 -
Objective : flt - 3 ligand ( fins - like tyrosine kinase receptor - 3 ligand, fl ) was a recently described growth factor affecting early hematopoietic progenitor cells, that play a key role in the growth and differentiation of primitive hematopoietic cells. fl promotes the survival, proliferation, and differentiation of hematopoietic progenitors in synergy with other growth factors
Fms樣酪氨酸激酶受體3配體（ fms - liketyrosinekinasereceptor - 3ligand ， fl ）是一種新近發現的、能夠有效地刺激早期造血的細胞因子，可單獨或聯合其他細胞因子促進造血幹細胞的增殖。 -
Screening and constructional analysis of extracellular at the ligand binding domain of the vascular endothelial growth factor receptor flt
胞外配體結合域的篩選及其結構分析 -
In sporophytically self - incompatible brassica, three s - linked genes, the pollen ligand scr, stigma receptor slg and srk, have been identified. in addition, four genes ( arc1, thl1, thl2 and mod ) that do not link to s locus have also been found, they are regarded as downstream protein factors of self - incompatibility ( si ) response, however, their biological function is not clear
在孢子體型自交不親和的蕓薹屬中，已經鑒定出3個主要與s位點緊密連鎖的基因，花粉中的配體scr和柱頭中的受體slg與srk ：另外鑒定出4個不與s位點連鎖的基因arc1 、 thl1 、 thl2和mod ，它們被認為是si反應的下游蛋白質因子，但是對它們的生物學功能了解的還比較少。 -
These can include animal - based, cell culture - based, biochemical, or ligand / receptor - binding assays
這些分析方法可以包括基於動物的，細胞培養的，生物化學的或配位體/接受體螯合的分析方法。 -
Proteinmicroarrays are now becoming very popular due to their possible futureapplications in the study of nucleic acid - protein, protein - protein, ligand - receptor, drug - protein target, and enzyme - substrate interactions
蛋白晶元正在成為相當受歡迎，由於他們的未來可能應用在研究核酸蛋白、蛋白質，配體受體藥物靶蛋白和酶基板互動 -
Apolipoprotein e, a 34kda protein composed of 299 amino acids, is a multifunctional molecular, which is an important functional component of chylomicrons and very low density lipoprotein, intermediate density lipoprotein and high density lipoproteins. as a ligand for the low density lipoprotein receptor ( ldlr ), it plays an important role in the metabolism of plasma lipoproteins
載脂蛋白e （ apoe ）是34kda大小的多功能分子，由299個氨基酸組成，是cm 、 vldl 、 idl和部分hdl的組分，通過ldl受體途徑調控脂蛋白代謝，在脂類代謝中發揮重要作用。 -
The result indicates that the mg2 + ion around the binding site is very important to stabilize the binding of the ligand to the receptor. the binding free energy estimated by the empirical function favors the system with one mg2 + ion, in which the free energy is about 5 kcal / mol less than the system with mg2 + ion
含有mg2 +離子的情況下比不含mg2 +離子的體系之間的自北京工業大學工學碩士論文一由能之差為一5kcal m ，結果說明結合位點處的mg 『 」離子對穩定配體與受體的結合起了重要作用。 -
Generally, the protein - protein docking procedure is composed of four stages : searching of the binding modes of the receptor and the ligand, filtering of docked modes to eliminate the irrational docked structures, optimizing the structures, evaluating the docked modes with the refined scoring function and ranking them to obtain the near - native structures
通常，蛋白質蛋白質分子對接包括四個階段：搜索受體與配體分子間的結合模式，過濾對接結構以排除不合理的結合模式，優化結構，用精細的打分函數評價、排序對接模式並挑選近天然構象。 -
The latter plays a very important role in the study of the mechanism and dynamics of the recognition. it includes the molecular modeling, confirming the binding sites, the calculation of interactions between receptor and ligand, the docking research of the complex, the calculation of dynamic and thermodynamic properties etc. many theoretical calculation methods are involved, such as quantum chemistry, molecular mechanisms, molecular dynamics, monte carlo method and free energy calculation and so on
其中計算機模擬方法是研究分子識別機制及其動態過程的重要途徑，包括底物及受體分子模型的構建、底物及受體相互作用位點的確定、相互作用力的計算、底物及受體分子的對接及其動態過程的研究、體系熱力學及動力學性質的計算等方面內容。 -
Mekler idlis ( m - i ) pair theory suggests that each codon - directed amino acid residue in a sense peptide may make a specific pair - wise interaction with the corresponding complementary codon - directed residue in the complementary peptide. ahbs theory suggests also the parts between / in the proteins that are capable of interacting specifically. the interaction between receptor and ligand is the recognition and interaction between proteins. if the receptor is the sens e peptide, the ligand, which can specifically bind to it, must have one or several antisense peptides. these antisense peptides muat be located at the key place which has relationship with the function of the ligand
Ahbs （反義同源盒）理論和分子識別理論描述了蛋白分子內和蛋白分子間可以特異結合的區域結構具有正義與反義的關系。受體與配體的相互作用實質上是蛋白質分子間的識別、結合和相互作用的過程。將受體看作是有義肽，那麼可與之特異結合的配體分子中可能存在一段或多段反義肽，而且其存在的部位是配體功能的關鍵位置。 -
The self - incompatibility is involved in a signal transduction process resulted from the interaction between ligand and receptor. up to now, some achievements for ligand and receptor have already been made, but the research progress on downstream protein factors is slower than that of upstream components, highlighting the downstream proteins in priority of research. some downstream components have not been isolated, which are similar to the unknown function of those isolated ones
自交不親和反應是一種配體和受體相互識別的信號傳導過程，在這一過程中，對配體和受體的研究已經取得突破性成果，而對下游的磷酸化蛋白研究相對上游受體來說要緩慢得多，所以對信號傳導的下游組分研究顯得尤為重要，特?是下游還有許多未分離到的組分，而分離到的組分其功能還不清楚。 -
Measuring the adhesion forces of ligand - receptor bonds using functionalized carbon nanotube atomic force microscopic tips
碳納米管原子力顯微鏡針尖的研究進展 -
Because the large conformational changes occurring upon complex formation are frequently confined to the protein surface, especially for the side chains of flexible amino acids arg, lys, asp, glu and met, the locations of the mass centers and the values of radii of these residues are modified for modeling protein surface. this tolerates overlap in some degree between the amino acid side chains on the surfaces of the receptor and the ligand
由於蛋白質表面氨基酸殘基arg 、 lys 、 asp 、 glu和met具有較大的柔性，因此，北京工業大學工學博士學位論文一我們對蛋白質分子表面的這五種氨基酸模型作了修正，調整了殘基球心的位置和半徑的數值，使分子表面的氨基酸殘基在對接時具有一定程度的可交疊性。 -
Differentiation of 3t3 - l1 preadipocytes into adipocytes is induced by a combination of inducers, including a glucocorticoid, an agent that elevates cellular camp, and a ligand of the insulin - like growth factor - 1 receptor
3t3 - l1前脂肪細胞是在三種誘導劑（一種糖皮質激素，一種能夠提升胞內camp水平的試劑和一種類胰島素生長因子受體的配體）的誘導下分化成為脂肪細胞。
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