role activation 中文意思是什麼
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Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4
- arrestin2是趨化因子受體的一種重要的調節蛋白，本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用，反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制， cxcr4介導的趨化作用則被明顯抑制。 -
2. the proapoptotic effects result from the reduction of erk, activation of jnk during treatment of bfgf and p38 also has some role in this process
Bfgf作用於u2 os細胞引起的erk活性抑制和jnk長時程激活共同介導了u2 os細胞凋亡的發生， p38也在一定程度上參與了這個過程。 -
Wavelet analysis and neural network have been researched. based on bp neural network, analysing the features of the bp neural network ' s activation function and the structure of the bp neural network, wavelets neural network is constructed with wavelet function. fourier transform has a important role on signal processing, so the fourier transform is introduced. a function ' fourier transform is analysed. after introducing the concept of the wavelet analysis, a serval wavelet functions is given out, so the knowledge of wavelet analysis is better understood. the multiresolution analysis has a important role on constructing wavelet function and understanding the wavelet transform
小波分析和神經網路得到了廣泛的研究，小波神經網路是在bp神經網路的基礎上，考慮和分析了bp神經網路的激勵函數的特點，以及bp神經網路的結構，結合了小波分析的知識而構造的。傅里葉變換在信號的處理起重要的作用，所以介紹了傅里葉變換、離散傅里葉變換和加窗傅里葉變換，並對一函數作離散傅里葉變換分析。 -
Furthermore, k + ionophore valinomycin and k + channel opener diazoxide alone induced neuronal apoptosis and caspase - 3 activation. besides, katp channel blockers tolbutamide and glybenclamide also showed neuroprotective effects and decreased caspase - 3 activation after hypoxia / reoxygenation. while the role of katp channels in neuronal apoptosis is not clear
為進一步證實鉀通道在缺氧復氧誘導的神經元凋亡中的作用，我們採用了鉀通道開通劑100pmdiazoxide及鉀離子載體50nmvallnomycln 。 -
In conclusion, these results suggest that the expression and activation of stat3 may play an important role during embryo implantation and decidualization
總之， staf3的表達及激活可能在小鼠的胚胎著床和蛻膜化過積中起巫要作川。 -
In influence human resources effectiveness many aspects, the salary is playing the role in the activation human resources potential aspect which does not have may substitute, through is positive but the valuable salary decision - making, we may display the salary the strategic strut function which develops to the enterprise
在影響人力資源效用的多個方面，薪酬在激活人力資源潛力方面發揮著無可替代的作用，通過積極而有價值的薪酬決策，我們可以發揮薪酬對企業發展的戰略支撐作用。 -
The important role of activation of gabab receptors in acupuncture analgesia
受體在針刺鎮痛中的作用 -
Bottom - up processing and feature detecting theory based on strong electrophysiological evidences has played a dominant role in the visual research for long time. people know top - down processing just by common sense. knowledge or experience are recalled from memory by reactivation of their neural representations and affected visual processes. however recently, researches from human and monkey provide experimental evidences for top - down processing. first, mnemonic representation of visual objects and faces, located in the ventral processing stream of visual perception in monkey, provide the best evidences of how neuronal codes are created by neurons that have the special ability to link the representations of temporally associated stimuli ; second, experiments suggest that not only bottom - up signals from the retina but also top - down signals from the prefrontal cortex can trigger the retrieval of associative codes, which may serve as a neural basis both for the conscious recall and for the visual processes affected by top - down processing further studies will improve people s understanding of the causal relation of activation and behavior by use of combined fmri and electrophysiology or lesion studies
聯想性編碼是通過學習由一些具有特殊功能的神經元建立的，這些神經元具有將時間性關聯刺激的表徵聯系起來的能力。其次，不僅來自視網膜的底-頂信號，而且來自前額葉的頂底信號都能觸發聯想性編碼的提取，既可以作為有意識回憶的神經基礎，又是頂-底加工影響視覺過程的基礎。腦損傷病人研究具有高時間解析度的人類功能性核磁共振成像functional magnetic resonance imaging ， fmri和猴fmri研究以及猴細胞電生理分析相結合，將進一步加強人們對視覺腦機制的全面理解。 -
Backgroud : the activation of antigen - specific t cells plays a vital role in the initiation and development of some immune - related diseases, such as transplant rejection and allergic diseases
背景：抗原特異性t細胞的活化在一些免疫相關疾病（如移植排斥反應、變應性疾病）的發生、發展中起著主導性的作用。 -
The results were as follows : ( l ) the pre - incubation of pmr induced the exocytosis of the cortical granules ( cgs ) in the oocytes and reduced the quantity of the microvillus on the surface of oocytes ; ( 2 ) the matrix of cg might migrate to the surface of plasma membrane of oocytes after pmr pre - treatment. ( 3 ) incubation of zona - free hamster eggs with spermatozoa pretreated with pmr a ntiserum was associated with a dose - dependent significant reduction in the number of spermatozoa binding to the oolemma, compared with a contraband with a dose - dependent reduction of the fertilization rate and the penetration index. the results indicate that mr of human sperm plays an important role in sperm - oocyte fusion and oocyte activation
結果顯示： （ 1 ）人精子mr能夠誘發去透明帶金黃地鼠卵母細胞中皮質顆粒的胞吐，並引起卵母細胞膜表面微絨毛形態和數量發生改變； （ 2 ）皮質顆粒胞吐后，其內容物可結合到卵膜表面； （ 3 ）抗mr抗血清預處理精子可抑制精子與卵子的結合與融合，使受精率、穿透指數和結合指數下降，並均有劑量依賴性。以上結果提示，人精子mr在受精過程中起重要作用，其主要作用可能是介導精-卵膜融合併促進卵母細胞的活化。 -
Role of p38 mapk activation in glucose - induced microvascular hyperpermeability of rats
激活在高血糖致大鼠微血管通透性增高過程中的作用 -
These results suggest : 1 ) anion channels play an important role in the regulation of blood vascular tone ; 2 ) ne - stimulated contraction is not influenced by extracellular sodium ; 3 ) vascular tone can be affected by anion channel ' s activity ; 4 ) the activation of anion channels do not depend on release of intracellular calcium ; 5 ) anion channels may be involved in the regulation of vascular tone through modulating the influx of extracellular calcium and the release of intracellular calcium
陰離子通道對血管平滑肌細胞外鈣內流和內鈣釋放都有調節作用。本研究表明，血管張力的維持可能主要與陰離子通道的活動狀態有關。陰離子通道很可能是通過調節血管平滑肌細胞外鈣內流和內鈣釋放兩個途徑來發揮調節血管張力的作用。 -
This machine is delivered through biological electromagnetism wave induction flat to the whole body of human body, human body in take over biological electromagnetism wave signal after, in body various functions quilt continuous activation, running returns to normal, so, reach the role of lasting health protection, massage and row poison
該機通過生物電磁電磁波感應片傳送至人體全身，人體在接收到生物電磁波信號后，體內各種機能被連續激活，恢復正常運作，從而達到持久保健、按摩、排毒的作用。 -
Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation, which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1. under the same condition, spla 2 can induce intracellular ceramidegeneration. moreover, exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf, suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events
在相同的條件下，分泌型磷脂酶a亦能誘導細胞內神經酰胺生2成的增加；外源性的神經酰胺類似物也能有效的抑製表皮生長因子誘導的這些生物事件，提示神經酰胺在分泌型磷脂酶a所介導的細胞死亡和信號傳導事件2中起著重要的作用。 -
The role of human reactions ( intervening historical contingencies ) points out that the main purpose behind predictions was not prognostication but activation
人回應（干預性歷史偶發）的角色指出，在預言之後的主要目的不是預測未來，而是激勵。 -
Moreover, at non - heat - shock temperature, dna - binding activity of the hsf was also induced by directly adding cam to a whole cell extract but not by the same concentration of bsa. our observations further confirm the role of ca2 + in activation of hsf in plant and provide the first example of the role of cam in regulation of the dna - binding activity of the hsf
以上結果在植物中進一步證實了ca ~ （ 2 + ）可促進hsf的dna結合活性，並首次表明cam也可促進hsf的dna結合活性，由此提出ca ~ （ 2 + ） - cam信號系統影響熱激基因的表達可能是通過調節hsf的活性而實現的。 -
We summarize the dual role of telomeres in cancer, and the relationship between telomerase activation and tumours
筆者綜述了端粒的縮短所扮演的雙重角色，以及端粒酶的激活與腫瘤之間的關系。 -
To answer this question, a bispecific, trifunctional antibody constructs which can not only target block virus incorporated rca, but also can induce complement activation by it ' s fc fragment were designed and constructed and iv the role of this kind of bispecific antibody in virus neutralization was studied. 1. to test our idea, human immunodeficient virus ( hiv ) and enveloped extracellular virus ( eev ) of vaccinia virus ( vv ) were selected in our study because of their complex immune evasion stratiges, their threaten to humans, and because both these two kinds of virus can escape complement attack by incorporating host rca into their envelope
以嚴重危害人類健康，且具有復雜免疫逃避機制的有包膜的hiv病毒及痘苗病毒的eev病毒為研究對象，首先對它們逃避補體攻擊的現象進行了驗證，探討了宿主膜補體調節蛋白cd55 、 cd59與hiv病毒及eev病毒免疫逃避的關系，評價了病毒結合的這兩種補體調節蛋白作為本研究提出的，通過消除病毒逃避補體攻擊的機制來恢復病毒對補體攻擊的敏感性，提高補體抗病毒效率這一抗病毒策略的靶點的可能性。 -
Increasing evidence indicated that peripheral iglurs play an important role in the process of activation of nociceptors. recently, bhave et al. showed that group i mglurs, including mglur1 and mglur5, are also located in terminals of primary afferent fibers by morphological examinations
本研究採用行為學和功能形態學的方法（ formalin引起的fos表達） ，試圖從功能上證實分佈在初級傳入神經元外周軸突上的mglurs參與傷害感受器的激活，在外周痛信號的產生中發揮重要作用。 -
The establishing history of china ' s securities and futures market is over ten years, in such a short period of time, the securities and futures market has developed rapidly to form a rather completed market system with preliminary scale, which plays an important role in the well allocation of resources, the establishment of modern enterprise system and the activation of capital markets as well as the macro adjustment of economy
我國的證券、期貨市場在建立以來的十余年中，發展迅速，已形成了初具規模、比較完善的市場體系，對優化資源配置，建立現代企業制度和活躍資本市場發揮了積極的作用，在宏觀經濟調控中扮演著十分重要的角色。
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