schistosoma japonicum infection 中文意思是什麼

schistosoma japonicum infection 解釋
日本血吸蟲感染
  1. The mouse model of hepatic egg granuloma of schistosoma japonicum confirmed that np30 has sensitizing effect on formation of hepatic egg granuloma, active immunity in sheeps and mice with np30 can induce good protecti on against infection with schistosoma cercariae and reduces immunopathologic damage to host, np30 plays a significant down - modulatory role to hepatic granuloma and fibrosis

    以往的研究業已證明np30對蟲卯肉芽腫的形成具有致敏作用，並有十分顯著抗蟲卵肉芽腫肝纖維化作用，用np30主動免疫小鼠、山羊可減輕日本血吸蟲對宿主造成的免疫病理損害。
  2. Yherefore, many researchers have shown great concern with the development of vaccines to against schistosomiasis. at early stage, the research of vaccines of schitosomiasis was centered on dead vaccine and athenuated cercaria of schistosomes while molecular vaccine and athenuated cercaria of schistosomes while molecular vaccine is currently the focus of research with anti - infection protective immunity as its main concern. guan xiaohong and zhao weixian ( 1986 ) certified that the allergen of egg granulonma of schistosoma japonicum might firstly come from gut associated antigen ( gaa ) of schistosomula and adult worm and that daa had cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ) ; and the gaa of schistosoma japonicum might play a sensitizing role in egg granuloma formation

    Np30主動免疫c57bl 6對尾蚴攻擊感染產生42 . 05的保護力，肝組織減卵率為66 . 63 ； balb c和昆明種小鼠的保護率分別為39 . 53和50 . 46 ；免疫山羊可誘導42 . 78的減蟲率，肝組織減卵率為35 . 83 ，糞減卵率為25 ，並可明顯抑制肝臟蟲卵肉芽腫的大小，肉芽腫數量明顯減少，纖維化減輕，體重明顯增加，因此np30是南京醫科大學博士學位論文很有希望的抗日本血吸蟲病疫苗侯選分子。
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