shiga toxin 中文意思是什麼

shiga toxin 解釋
志賀毒素
  1. Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn

    蓖麻毒素進入細胞的機理不甚明了,一般認為是rtb先與細胞膜受體結合,主要經過受體介導的內吞作用進入吞噬體,然後沿著內體、高爾基體、內質網等逆向分泌途徑,有序地運輸到內質網,最後從內質網轉位進入細胞漿,在胞漿內攻擊核糖體,從而抑制蛋白質的合成,導致細胞死亡。
  2. To dress the question if other virulence gene were present in this kind of strains, 152 of 436 irp2 - hybridized strains were re - confirmed and selected for this study. the virulence genes or putative virulence genes detected by pcr or hybridization include heat stable toxin ( st ) & heat labile toxin ( lt ) for enterotoxigenic e. coli ( etec ), invasive plasmid antigen b ( ipab ) for enteroinvasive e. coli ( eiec ), epec adherence factor ( eaf ), epec secretion protein c ( espc ) for enteropathogenic e. coli ( epec ), hemolysin ( hlya ) and shiga toxins ( sltl and slt2 ) for enterohaemorrhagic e. coli ( ehec ) and eaggec probe for entero - aggregative e. coli ( eaggec ). the prra and yc73 genes of pathogenicity associated island ( pai ) of urepathogenic e. coli ( upec ) and " o " island 28 ( rtx 615 ) gene was also detected, the later was a newly discovered putative pathogenicity island in e. coli o157 : h7

    為探討攜帶小腸結腸炎耶爾森氏菌的hpi毒力島的大腸桿菌是否具有其他已知的毒力基因,選取82株由原位雜交和pcr方法初篩irp2陽性的大腸桿菌菌株,進行在致瀉性大腸桿菌的25個毒力基因的檢測,包括腸產毒性大腸桿菌的熱穩定毒素st和熱不穩定毒素lt ,腸侵襲性大腸桿菌的侵襲蛋白b基因ipab ,腸致病性大腸桿菌的eaf 、 espc基因,腸出血性大腸桿菌的溶血素hly 、志賀毒素1 ( slt1 ) 、志賀毒素2 ( slt2 )基因,腸集聚性大腸桿菌的eaggec探針,以及在泌尿道致病性大腸桿菌和o157 : h7大腸桿菌中新發現的毒力島基因。
  3. All the five e. coli o157 : h7 strains isolated from patients with diarrhea and / or hus ( hemolytic uremic syndrome ) in 1999 are shiga - toxin ( stx ) gene positive and have the same pfge pattern

    研究發現, 1999年在江蘇省徐州市從腹瀉病患者、 hus患者分離的5株產生志賀毒素的大腸桿菌0157 : h7菌株,屬於一個pfge型。
  4. Shiga - like toxin, slt

    志賀樣毒素
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