soluble antigen 中文意思是什麼
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Yherefore, many researchers have shown great concern with the development of vaccines to against schistosomiasis. at early stage, the research of vaccines of schitosomiasis was centered on dead vaccine and athenuated cercaria of schistosomes while molecular vaccine and athenuated cercaria of schistosomes while molecular vaccine is currently the focus of research with anti - infection protective immunity as its main concern. guan xiaohong and zhao weixian ( 1986 ) certified that the allergen of egg granulonma of schistosoma japonicum might firstly come from gut associated antigen ( gaa ) of schistosomula and adult worm and that daa had cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ) ; and the gaa of schistosoma japonicum might play a sensitizing role in egg granuloma formation
Np30主動免疫c57bl 6對尾蚴攻擊感染產生42 . 05的保護力，肝組織減卵率為66 . 63 ； balb c和昆明種小鼠的保護率分別為39 . 53和50 . 46 ；免疫山羊可誘導42 . 78的減蟲率，肝組織減卵率為35 . 83 ，糞減卵率為25 ，並可明顯抑制肝臟蟲卵肉芽腫的大小，肉芽腫數量明顯減少，纖維化減輕，體重明顯增加，因此np30是南京醫科大學博士學位論文很有希望的抗日本血吸蟲病疫苗侯選分子。 -
Guan et al ( 1991 ) established a strain of monoclonal anti - idiotypic antibody np30 ofschistosomajaponicum, which is an internal image anti - idiotypic antibody of gut associated antigen ( gaa ), its antibody isotype is igm. np30 has a partial cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ). np30 molecule has been researched on many aspects
管曉虹等（ 1991 ）建立了一株日本血吸蟲單克隆抗獨特型抗體np30 ，已證實為腸相關抗原（ gaa ）的內影像抗獨特型抗體，其抗體同型為igm ，與可溶性蟲卵抗原（ sea ）及膜相關抗原（ maa ）有部分交叉反應。 -
Guan xiaohong, et al. ( 1991 ) established a strain of monoclonal anti - idiotypic antibody np30 of schistosoma japonicum, whice is an internal image antigen of gut associated antigen ( gaa ), its antibody isotype is igm. np30 has a partial cross - reaction with soluble egg antigen ( sba ) and membrane associated antigen ( maa )
管曉虹等建立的日本血吸蟲單克隆抗獨特型抗體（ anti - id ， ab _ 2 ） np30是腸相關抗原（ gaa ）的內影像anti - id ，與可溶性蟲卵抗原（ sea ）有交叉反應，可替代蟲源性抗原用於血吸蟲病免疫診斷和抗病疫苗的研究。 -
Detection of antigen - binding affinity of soluble mg7 scfv elisa was adopted to examine the antigen - binding affinity of soluble mg7 scfv ; competitive elisa was performed to test the inhibitory ratio of soluble mg7 scfv to the binding affinity of mg7 mab with its relevant antigen
El舊a拐成惴現2個克隆的可容牲mg7seem明顯的抗原結合舌隊其a分別為0 832和0 912 ，均高出附性對照（ 0 -
After the recombinant plasmid pcdna3. 1 / ts87 was identified by digestion of hindlll and bamh i, it transformed into cos7 by lipofectamine. expression product was identified by immunohistochemical method, sds - page and western - blot. the immunocytochemistry result has shown that specific brown - staining grains were found in the cytoplasm of cells transformed by recombinant plasmid versus not seen in cells transformed by pcdna3. 1 or normal cells ; the sds - page result has revealed that a band about 3 8kb was found in cell lysis transformed by recombinant plasmid versus not in cells transformed by pcdnas. l or normal cells ; the western - blot result has showed that only the band about 38kd was recognized by sera from rabbit infected by t. s artificially and sera from rabbit immunized with soluble antigen of t. s and with protein expressed by ts87 gene and by a monoclonal antibody of t. s
通過細胞的免疫組化，細胞裂解物的sds - page電泳， westem - blot分析檢測目的基因的表達情況。免疫組化結果顯示：重組質粒轉染的細胞質中有棕褐色顆粒，而空載體轉染細胞及正常細胞無此現象；細胞裂解物sds - page電泳結果顯示：只有重組質粒轉染的細胞在約38kd處有明顯的蛋白帶，這與理論計算的ts87基因表達蛋白的分子量為38kd基本一致； western - blot分析結果顯示：約38kd的蛋白帶能夠分別被旋毛蟲感染兔血清，成蟲蟲體可溶性抗原免疫兔血清， ts87基因原核表達蛋白免疫兔血清（ ts87血清）以及一株具保護性的旋毛蟲單抗特異識別。 -
Urea soluble fraction of bovine melanin associated antigen and experimental study on its uveitogenic activity
脲溶性牛黑素相關抗原的提取及其致葡萄膜炎活性的初步研究 -
Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc
而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。 -
Ts87 gene fragment was picked out by screening adult t. s cdna library using sera of rabbit raised against soluble antigen of t. s and using sera of rabbit infected artificially with t. s. the ts87 fragment was ligated to vector pcdnas. l, which contains a cmv promoter / enhancer
本研究採用通過免疫篩庫得到的旋毛蟲抗原基因片段ts87與載體pcdna3 . 1連接。該載體含有人類巨細胞病毒（ cmv ）的高效啟動子和增強子，是一種外源基因在哺乳動物細胞內高效表達的理想載體。
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