spla 中文意思是什麼

spla 解釋
其武裝力量稱「蘇丹人民解放軍」
  1. Itwas observed that sphingomyelin plays anegative regulatory role on the activity of spla 2, resulting in a strong inhibition on spla 2 - induced cell death

    我們觀察到，鞘磷脂對分泌型磷脂酶a的活性起著負2調控作用，它能有效的抑制分泌型磷脂酶a2對細胞的殺傷作用。
  2. Spla is able to induce the intracellular ceramide 2 2 generation followed by programmed cell death

    分泌型磷脂酶a能誘導細胞的程序化死亡，並伴隨有細胞2內神經酰胺生成的增加。
  3. Conversely, the intracellular sphingomyelinase ( smase ) can greatly enhance the cell death inducing effects of spla 2

    相反，鞘磷脂酶則能顯著增強分泌型磷脂酶a對細胞的毒性作用。
  4. The presented study provided novel experimental evidences for understanding the mechanism of the biological effects of spla 2

    本研究為更深入的了解分泌型磷脂酶a介導生物學效應時2所涉及的機制提供了新穎的實驗證據。
  5. To study the biologic effects and the underlying mechanism of secretory phospholipase a 2 ( spla 2 ) and ceramide, we firstly investigated the relationship between certain lipid signalingmolecules - mediated signal transduction and the spla - induced cell death

    為了研究分泌型磷脂酶a2和神經酰胺對細胞產生的生物學效應及其機制，我們首先探討了某些脂類活性分子介導的信號傳導與分泌型磷脂酶a誘導的細2胞死亡之間的關系。
  6. Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation, which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1. under the same condition, spla 2 can induce intracellular ceramidegeneration. moreover, exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf, suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events

    在相同的條件下，分泌型磷脂酶a亦能誘導細胞內神經酰胺生2成的增加；外源性的神經酰胺類似物也能有效的抑製表皮生長因子誘導的這些生物事件，提示神經酰胺在分泌型磷脂酶a所介導的細胞死亡和信號傳導事件2中起著重要的作用。
  7. Both spla 2 and ceramidehave been shown to inhibit bradykinin -, and pma - induced phospholipase d activation. these results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways. in addition, we also found that spla can 2 down regulate theepidermal growth factor ( egf ) receptor activation

    此外，我們還發現分泌型磷脂酶a能下調表皮生長因子受體的活化，它能明顯的抑製表皮生長因子誘導2的受體自身磷酸化，並抑製表皮生長因子誘導的磷脂酶d活性和磷脂酶c - g的1酪氨酸磷酸化。
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