t antigen 中文意思是什麼

t antigen 解釋
t 抗原
  • t : 中世紀羅馬數字的160。
  • antigen : n. 【醫學】抗原。
  1. Dendritic cells are characterized by their ability to efficiently present antigen, and are uniquely equipped to stimulate naive t cell responses. immature dendritic cells acquire antigens from throughout the peripheral body, then migrate to t - lymphocyte - dependent areas of lymph nodes. thus, dendritic cells act as bridges, operating at the interface of innate and acquired immunity

    作為機體免疫系統中功能最強的專職性抗原提呈細胞（ antigen - presentingcells ， apc ） ，樹突狀細胞（ dendriticcells ， dc ）能高效地攝取、加工處理和提呈抗原，具有較強的遷移能力，並能顯著地激活初始型t細胞以啟動t細胞免疫應答反應，此外， dc與b細胞以及nk細胞等也存在著相互作用，可見， dc在連接天然免疫和獲得性免疫之間起著非常重要的作用。
  2. T cell will be apopotosis, clone depletion and / or anergy, in turn inducing an antigen - specific tolerance. ctla4 ( cytotoxic t lymphocyte associated antigen 4 ), a prominent negative costimulator, can competitively bind with b7, and block b7 - cd28 pathway and t cell activation by producing inhibitory singals

    Ctla4 （ cytotoxictlymphocyteassociatedantigen4 ）作為一種主要的共刺激負調節劑，可競爭性結合b7分子，阻斷b7 - cd28途徑、並通過產生抑制性信號使t細胞活化障礙。
  3. Establishment of an immortalized neural precursor cell line with a temperature - sensitive mutant of sv40 large t antigen

    溫度敏感型基因永生化神經前體細胞系的建立
  4. It waves a piece of antigen that acts as a signal so that t cells can rush in and dispatch the interloper

    它揮舞著這一小塊抗原充當信號，於是t細胞迅速趕來，把入侵者給除去。
  5. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  6. Because of the difficulties on diagnosis and treatment, it is very important for the prevention of trichinosis. trichinella spiralis ( t. s ) has a complex life history and a variety of antigen components, so, despite of a lot of studies, no prevention measures specific for t. s has been found until now

    旋毛蟲病的診斷和治療都比較困難，因而預防顯得尤為重要。由於旋毛蟲生活史的復雜性和抗原的多樣性，雖然近年來許多學者進行了多方面的研究，但迄今為止，尚未發現免疫預防旋毛蟲病的有效措施。
  7. Hi our study, dendritic cells ( dcs ) were derived from the cultivation of peripheral blood monocytes in vitro successfully. then to observe whether dcs transfected with carcinoembryonic antigen ( cea ) - vaccinia recombinant virus ( rv - cea ) can induces cytotoxic t lymphocyte - mediated cea - specific immunity in vitro

    體外成功地完成了cd14 +單核細胞來源的樹突狀細胞（ dc ）的培養，並進一步研究人癌胚抗原重組痘苗病毒（ rv - cea ）轉染dc后體外誘導的cea特異性細胞免疫。
  8. After the recombinant plasmid pcdna3. 1 / ts87 was identified by digestion of hindlll and bamh i, it transformed into cos7 by lipofectamine. expression product was identified by immunohistochemical method, sds - page and western - blot. the immunocytochemistry result has shown that specific brown - staining grains were found in the cytoplasm of cells transformed by recombinant plasmid versus not seen in cells transformed by pcdna3. 1 or normal cells ; the sds - page result has revealed that a band about 3 8kb was found in cell lysis transformed by recombinant plasmid versus not in cells transformed by pcdnas. l or normal cells ; the western - blot result has showed that only the band about 38kd was recognized by sera from rabbit infected by t. s artificially and sera from rabbit immunized with soluble antigen of t. s and with protein expressed by ts87 gene and by a monoclonal antibody of t. s

    通過細胞的免疫組化，細胞裂解物的sds - page電泳， westem - blot分析檢測目的基因的表達情況。免疫組化結果顯示：重組質粒轉染的細胞質中有棕褐色顆粒，而空載體轉染細胞及正常細胞無此現象；細胞裂解物sds - page電泳結果顯示：只有重組質粒轉染的細胞在約38kd處有明顯的蛋白帶，這與理論計算的ts87基因表達蛋白的分子量為38kd基本一致； western - blot分析結果顯示：約38kd的蛋白帶能夠分別被旋毛蟲感染兔血清，成蟲蟲體可溶性抗原免疫兔血清， ts87基因原核表達蛋白免疫兔血清（ ts87血清）以及一株具保護性的旋毛蟲單抗特異識別。
  9. Immortalization of human ovarian carcinoma cells induced by sv40 t antigen gene

    基因誘導的人卵巢癌細胞永生化
  10. Cea gene was transferred into human dcs, and specific anti - cancer effecs induced by the vaccine was observed. this test is part of my tutor ' s. hang you - tian has observed the induction of crcinembryonic antigen ( cea ) - specific cytotoxic t - lymphocyte responses in vitro when he transfected dcs with pcdna3 - cea, and has observed the immunity effects of the dcs ( pcea ) inoculateing against to ct 26 ( hcea + ) loaded in balb / c mice. after vaccination with the cea gene - modified dc, the survival time of the mice vaccinated with ct26 + ( cea + ) ws prolonged more potently than that of the mice vaccinatd with other dcs

    癌胚抗原（ carcinoebryonicantigen ， cea ）是一種研廠鄭州大學2002年碩士畢業論文轉染人癌胚抗原真核表達質粒的人樹突狀細胞的抗瘤作用究最為深入的腫瘤相關抗原（ tumorassociatiednigen ， taa ） ，在90的胃腸道腫瘤、 50的乳腺癌及70的非小細胞肺癌中有高水平的表達，是目前國際上公認的腫瘤標志物。
  11. The effect of 20 g / 100 g diet of lactalbumin ( l ), casein ( c ), soy ( s ) and wheat ( w ) protein on the immune responsiveness of c3h / hen mice has been investigated by measuring the humoral immune response to the t cell - independent antigen, tnp - ficoll

    摘要：本研究測量體液對t細胞抗原的免疫反應，探討不同的蛋白補充劑（包括乳白蛋白、酪蛋白、大豆蛋白及小麥蛋白）飼料（ 20克蛋白/ 100克飼料）對小鼠免疫反應的效果。
  12. Cells of the immune system taking part in tumor - host interaction include t cells, natural killer cells ( nk cells ) and antigen - presenting cells ( apc, such as dendritic cells, b cells, macrophages )

    參與腫瘤免疫的免疫細胞主要有t細胞， nk細胞和抗原提呈細胞（ apc ） 。
  13. The study of relation between t cells and desensitization of specific antigen in asthma

    細胞與哮喘特異性致敏原皮下脫敏療法的研究
  14. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  15. 3 immunogenicity of m3m4 loop recombinant peptide antigen of nr1, neuroexcitotoxicity protective effects and their mechanisms study of antiserum against m3m4 ( 1 ) to explore the immunogenicity of m3m4 loop recombinant peptide vaccine, m3m4 recombinant peptide was injected subcutaneously to immunize balb / c mice ( h - 2 ), cd4 / cd8 t lymphocytes subsets, the cytokine levels in serum and the liter of specific humoral response were detected with facs, indirect elisa and elisa separately

    ，抗血清還可以結合合成膚nps ，證明該表位具有免疫原性和抗原性。收集抗血清用於功能檢測。 （二） m3m4片段抗血清抗興奮毒性損害作用以臺盼藍染色法和原位末端標記（ tun 』 el ）法觀察抗血清對原代培養海馬神經元興奮毒性壞死和凋亡的保護效應。
  16. Dcs play a pivotal role in the development of antitumor immunity. t lymphocytes immune response induced by direct antigen - pulsed dcs can not maintain longer for peptides - mhc department or mhc molecules degeneration. the method of dcs loading with tumor antigen gene is another potential approach to enhancing and maintaining immune response

    在用抗原直接刺激dc時，由於抗原- mhc復合物解離或細胞mhc分子降解而不能維持所誘導的t細胞免疫應答，藉助載體把腫瘤抗原基因導入dc后腫瘤抗原在dc內的持續表達能增強其抗原提呈能力並能維持所誘導的免疫效應。
  17. Backgroud : the activation of antigen - specific t cells plays a vital role in the initiation and development of some immune - related diseases, such as transplant rejection and allergic diseases

    背景：抗原特異性t細胞的活化在一些免疫相關疾病（如移植排斥反應、變應性疾病）的發生、發展中起著主導性的作用。
  18. Using the grid - type method to partition the space, regarding the modeling data as the antigen and the fuzzy rules as the antibody, this method determines the structure of t - s system with immune theory and adopts the least square method to estimate consequent parameters of the linear rule

    該方法結合網格空間劃分方法，以建模數據為抗原，模糊規則為抗體，採用人工免疫原理確定系統結構，並應用最小二乘方法估計線性規則後件參數。
  19. Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc

    而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。
  20. Generation of simian virus 40 large t antigen gene transgenic mice and its expression

    轉基因小鼠模型的建立及其表達
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