t-cea 中文意思是什麼
t-cea
解釋
組織癌胚抗原-
Hi our study, dendritic cells ( dcs ) were derived from the cultivation of peripheral blood monocytes in vitro successfully. then to observe whether dcs transfected with carcinoembryonic antigen ( cea ) - vaccinia recombinant virus ( rv - cea ) can induces cytotoxic t lymphocyte - mediated cea - specific immunity in vitro
體外成功地完成了cd14 +單核細胞來源的樹突狀細胞（ dc ）的培養，並進一步研究人癌胚抗原重組痘苗病毒（ rv - cea ）轉染dc后體外誘導的cea特異性細胞免疫。 -
Conclusion : dendritic cells ( dcs ) can be derived from peripheral blood monocytes in vitro successfully treated with rhgm - csf of 1000 u / ml plus il - 4 of 500 u / ml. second, dcs from the patients of advanced carcinoma of large intestine were transfected with rv - cea, and then cocultured with autologous t cells. the cytotoxic activity against cea - secreting tumor cells were assessed and compared with those of t cells induced by dcs without rv - cea transfection
其次，用rv - cea轉染晚期大腸癌患者的dc ，再激發自體t細胞，然後檢測t細胞對cea分泌性腫瘤細胞的體外殺傷活性，並與未經rv - cea轉染的dc激發的t細胞及野生型痘苗病毒轉染的dc激發的t細胞進行對比。 -
Cea gene was transferred into human dcs, and specific anti - cancer effecs induced by the vaccine was observed. this test is part of my tutor ' s. hang you - tian has observed the induction of crcinembryonic antigen ( cea ) - specific cytotoxic t - lymphocyte responses in vitro when he transfected dcs with pcdna3 - cea, and has observed the immunity effects of the dcs ( pcea ) inoculateing against to ct 26 ( hcea + ) loaded in balb / c mice. after vaccination with the cea gene - modified dc, the survival time of the mice vaccinated with ct26 + ( cea + ) ws prolonged more potently than that of the mice vaccinatd with other dcs
癌胚抗原（ carcinoebryonicantigen ， cea ）是一種研廠鄭州大學2002年碩士畢業論文轉染人癌胚抗原真核表達質粒的人樹突狀細胞的抗瘤作用究最為深入的腫瘤相關抗原（ tumorassociatiednigen ， taa ） ，在90的胃腸道腫瘤、 50的乳腺癌及70的非小細胞肺癌中有高水平的表達，是目前國際上公認的腫瘤標志物。 -
Objectives firstly to prepare the vaccine of human dcs and tumor cells transfectde with pcdna3 - cea, and to observe the induction of carcinoembryonic antigen ( cea ) - specific cytotoxic t - lymphocyte responses in vitro
用脂質體將cea表達質粒轉染人dc ，觀察其對cea表達陽性的腫瘤的特異性免疫作用。 -
Although the above tumor cells express cea, it ca n ' t induce the immune response of the body, so, tumor cells can avoid the immune surveillance of the body and survive
上述腫瘤細胞表面雖有cea分子，但並不能激起機體針對cea的特異性免疫應答，所以這些腫瘤細胞能逃避機體的免疫監視，發展成腫瘤。 -
Results : dcs transduced with rv - cea are effective stimuli of t lymphocyte proliferation. t cells induced by dcs transfected with rv - cea showed specific cytotoxicity against cea - secreting tumor cells
結果，經rv - cea轉染的dc激活的t細胞增殖力強，且對cea分泌性腫瘤細胞具特異性殺傷活性。
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