transactivation domain 中文意思是什麼

transactivation domain 解釋
激活區
  • transactivation : 轉活
  • domain : n 1 領土,版圖;領地。2 管區,勢力圈;(特定動物等的)生長圈;(學問、活動等的)領域,范圍;【物...
  1. This result show the deleted fragment is n ' t the key domain to transactivation. 2 ) the mutant p6p2 translate a peptide includiing 165 amino acid and acted as inhibition to sv40 promote

    ( 63加152 1079氨基酸段)對sv40啟動子的均有轉錄激活活性,這表明缺失的氨基酸片段( 64 151氨基酸序列)對轉錄激活是非必需的。
  2. The predicated amino acid sequences contain two conserved functional domains : a dna - binding domain ( hmg - box ) and a transactivation domain. the conserved motif of group b homology lies immediate adjacent to c - proximal region of the hmg - box. similar structure and identity of sox2 gene among mammals, birds, amphibians and reptiles suggest that sox2 gene have evolutionary conserved roles

    進一步分析表明,已巴灘2編碼的238個氨基酸多膚鏈含有兩個保守的功能區域:位於n端的hmg盒區( 1一78aa )和位於c端的轉錄激活區( 131一236aa ) ,以及一個保守的特徵性b亞族同源區域( 79一90aa )與hmg盒區的c端相連。
  3. The comparative analysis of sequences indicated that the sequences of meq in different pathotypes are relatively conserved and the homology of the amino acid sequences is very high. the significant differences include two mutations in both mdv - 1 vaccine strains cvi988 / rispens and 814 strain : the deletion of a proline ( no. l93aa ), and this mutation is just exactly located in a 15 - amino - acid ( eelcaqlcstppppi ) repeat sequence within the c - terminal transactivation domain of meq protein ; and a point mutation with a shift from alanine ( a ) of all virulent strains to serine ( s ) was occurred on the no. 71 aa

    結果發現, mdv不同致病型的meq基因序列相對比較保守,它們相互間核苷酸和氨基酸序列的同源性均很高;但是,與所有七個致瘤性的mdv毒株相比,二個型弱毒疫苗cv1988 rispens株和814株均出現了兩個特徵性的突變:即第194位的p缺失性突變和第71位氨基酸由a變成了s的位點突變;缺失性突變恰恰位於meq基因中轉錄激活域內的一個多脯氨酸的重復序列( pppp )之中。
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