transduction of receptor 中文意思是什麼

transduction of receptor 解釋
感受器的換能作用
  • transduction : n. 1. 【物理學】能量轉換。2. 【生物學】轉導(作用)。
  • of : OF =Old French 古法語。
  • receptor : n. 【生物學】感受器;受體;【化學】接受器;受納體;【電學】感受器;接收器。
  1. Our previous studies showed existence of apoplast cam in the plant cell and cam had many extracellular functions. so it supposed cam may be one of important extracellular polypeptides and trigger the intracellular signal transduction by binding the receptor. in this study, radiolabelled ligand is used to investigate the binding characteristic of cam and a. thaliana protoplasts. and chemical crosslinking is employed to explore binding proteins in the membrane. at first, ( 35 ) ~ s - cam was produced using ( 35 ) ~ s - labeled amino acid mixture in e. coli. sds - page and autoradiograph indicated high - purified, high - specific radioactivity ( 35 ) ~ s - cam was obtained. electrophoresis of ( 35 ) ~ s - cam is the same as that of unlabeled cam with ca ~ ( 2 + ) or egta ; a quatitive of protoplasts was prepared by enzymolysis

    首先,用~ ( 35 ) s標記的氨基酸混合物喂養工程菌成功地制備了~ ( 35 ) s標記的擬南芥鈣調素( ~ ( 35 ) s - cam ) , ~ ( 35 ) s - cam純度高、放射活度高、 ca ~ ( 2 + )與egta存在時的電泳行為與未標記cam相同,可作為一種高靈敏性的探針用於進行受體學分析實驗;用擬南芥種子誘導愈傷,通過酶解制備了大量原生質體。
  2. The degradation of i k b and dissociation from nf - k b complex are essential process for activation of nf - k b. there is no report about whether cck - 8 inhibits nf - k b activity through inhibiting lps - induced degradation of i k b. the present study was designed to observe the regulatory effect of cck - 8 on changes of immune functions induced by lps, the receptor mechanism and signal transduction mechanism involving mapk, stat3 and i k b at different levels including in vivo and in vitro, in order to study its immunomodulatory effect on reversing es and its molecular mechanisms

    Ikb的降解、並從w兒b復合物上解離是w4b激活的必需過程。 ccks是否通過抑制lps誘導的ikb降解,從而抑制nf幾b激活尚未見報道。本研究在整體、細胞及分子水平,觀察了ccke對lps引起的免疫功能改變的調節作用,研究了其受體機制及mapk 、 stat3和ikb的信號轉導機制,以探討cck七抗es時的免疫調節作用及其分子機制。
  3. For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development

    如g蛋白偶聯受體通過g蛋白介導產生胞內信使( camp , cgmp , dg , ip _ 3 )將胞外信號傳遞到胞內,從而引起生物學效應;內質網上也存在著一些跨膜蛋白,其中一些與蛋白質的合成及運輸有關,一些與物質代謝有關,如葡萄糖- 6 -磷酸酶。
  4. Ip3 - ip3 receptor ( ip3r ) interaction mediates the release of ca2 + from the endoplasmic reticulum in response to many different extracellular stimulus. for higher plants, however, though it is now generally accepted that ip3 participates in signal transduction in many important cellular processes, only limited evidence is available for the presence and properties of the ip3r - like protein so far. here, using the immunological methods with an antibody raised against a mammalian inositol 1, 4, 5 - triphophate receptor ( type 1 ), we found that, 1 ) the antibody across - reacted the proteins with about 200kd in microsomes from oryza sativa and about 200kd from arabidopsis thaliana respectively

    本實驗用sds - page電泳和免疫印跡的方法,用哺乳動物大鼠三磷酸肌醇受體的多肽做抗體對類三磷酸肌醇受體蛋白鑒定,結果表明:抗體與水稻和擬南芥微粒體蛋白分子量大約為200kd的蛋白交叉反應,同時還發現在水稻微粒體蛋白62kd和擬南芥微粒體蛋白45kd處有交叉反應的蛋白條帶存在,表明在植物中有類三磷酸肌醇受體蛋白的存在;用免疫膠體金方法,發現類三磷酸肌醇受體蛋白主要分佈於液泡膜和細胞質膜上。
  5. Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc

    而t細胞的活化除需要t細胞受體( tcr )與抗原呈遞細胞( antigenpresentingcell , apc )表面的抗原肽- mhc復合物結合所形成的第一信號外,還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號(亦稱第二信號或輔助刺激信號, costimulatorysignal )的參與。
  6. Effects of huanglian jiedu decoction on signal transduction of insulin receptor and insulin receptor substrate in adipose tissue of insulin resistant rats

    黃連解毒湯對胰島素抵抗大鼠脂肪組織胰島素受體及其底物信號轉導的影響
  7. However, there are limitied documents about receptor signal transduction within uterine endometrium during implantation. the factors regulating endometrial receptivity remain poorly understood. the objective of this dessert is to investigate mapk ' s expression and location in differnt days of pregnancy, as more important, we try to elucidate the relation of mapk and the receptivity of endometrium

    本課題組經研究還發現lewis ~ y寡糖在植入中呈階段特異性表達,可影響其他如lif 、 egf 、 fn (纖連蛋白)和mmps (基質金屬蛋白酶)等因子的表達,推測其可能作為一種信息分子經某種轉導途徑(例如mapk )而發揮作用。
  8. Pretreatment with the phospholipase c inhibitor u73122 ( 5 umol / l ) significantly inhibited the il - 2 - induced depression of contraction. conclusion : it is concluded that the effect of il - 2 on contraction of ventricular myocytes is mediated via the cardiac k opioid receptor, and the post - receptor signal transduction pathway includes a ptx sensitive g protein and phospholipase c. 2 effect of interieukin - 2 on intracellular calcium tran

    5 200u ffil )濃度依賴性地降低單個心室肌細胞電刺激誘導的鈣瞬變幅度,使舒張末鈣水平升高; ( 2 ) il 2 ( 200u ml )使咖啡因誘導的肌漿網內貯鈣的釋放降低: ( 3 ) 50偷i熱失活!
  9. To study the mechanisms of ischemic brain injury the excitotoxicity more thoroughly, and the therapeutic approach of ischemic brain injury, we in this research established the rational in vitro models of brain slice and primary neuronal cultures, searched new nmda receptor antagonists, and analyzed the characteristics of signal transduction triggered by nmda

    為了更加深入地研究腦缺血損傷機制,探討腦缺血損傷中起主要作用的興奮性氨基酸毒性一機制及其治療藥物,本研究進一步建立了腦片和神經元水平的體外腦缺血模型;探討了新類型n 』 md損傷對抗藥物;還對nmd的信號轉導特點作了分析。
  10. Role of platelet - derived growth factor receptor - mediated signal transduction in myocardial hypertrophy of spontaneouslyhypertensive rats

    血小板源生長因子受體介導的信號轉導在自發性高血壓大鼠心肌肥大中的作用
  11. The self - incompatibility is involved in a signal transduction process resulted from the interaction between ligand and receptor. up to now, some achievements for ligand and receptor have already been made, but the research progress on downstream protein factors is slower than that of upstream components, highlighting the downstream proteins in priority of research. some downstream components have not been isolated, which are similar to the unknown function of those isolated ones

    自交不親和反應是一種配體和受體相互識別的信號傳導過程,在這一過程中,對配體和受體的研究已經取得突破性成果,而對下游的磷酸化蛋白研究相對上游受體來說要緩慢得多,所以對信號傳導的下游組分研究顯得尤為重要,特?是下游還有許多未分離到的組分,而分離到的組分其功能還不清楚。
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