tyrosine kinase 中文意思是什麼

tyrosine kinase 解釋
酪氨酸激酶
  • tyrosine : n. 【生物化學】酪胺酸；3-對羥苯基丙氨酸。
  • kinase : n. 【生物化學】激酶。
  1. Pka, receptor tyrosine kinase ( trk ) and classical nuclear receptor of gc were not involved in the gc " s activation of mapks the second part studied the nuclear translocation of gc activated mapks, mainly p38 and jnk, with laser confocal microscopy. the results showed that : 1

    Gc激活的mapks的激活不需要pka酪氨酸激酶受體trk及經典gc核受體的參與第二部分是研究gc激活的mapks的核轉位，主要是p38和jnk ，用激光共聚焦顯微鏡觀察到以下結果： 1
  2. Anti - implantation effects of protein tyrosine kinase inhibitors

    酪氨酸蛋白激酶抑制劑的抗生育效應及研究進展
  3. Is pdgf tyrosine kinase inhibitor effective in pancreatic cancer

    Pdgf受體酪氨酸激酶抑制劑在胰腺癌中是否有作用
  4. The enzyme digest analysis shows that the arm repeats of c - terminal are conceivably conservative domain. in arc1 protein, there are some active sites including n - glycosylation sites, camp - and cgmp - dependent protein kinase phosphorylation sites, protein kinase c phosphorylation sites, casein kinase ii phosphorylation sites, tyrosine kinase phosphorylation sites, n - myristoylation sites, amidation sites and leucine zipper pattern. it probably take part in the signaling process of self - incompatibility

    同時在arc1蛋白質中還發現了拉鏈結構和多個磷酸化位點，包括camp和cgmp依賴的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨酸激酶磷酸化位點、糖基化位點等，拉鏈結構為arc1蛋白之間及與其它蛋白的相互作用提供了可能，而磷酸化位點是arc1參與信號傳導過程所必需的。
  5. The cyst cells enclosing spermatomeres maybe synthesize a kind of scf - like protein, which can recognize specially the c - kit receptor on the cellular membrane of spermatomeres. then c - kit is activated, dimerizing and autophosphorylating. at the same time, the tyrosine kinase domain of c - kit is activized, which phosphorylates the proteins that have sh2 domain

    精母細胞周圍的囊細胞可能合成scf樣蛋白，特異地識別精母細胞膜上的c - kit受體，並刺激c - kit發生二聚化、自體磷酸化，激活胞內酪氨酸激酶活性，活化具有「 sh _ 2結構域」的靶蛋白，可能通過一系列信號級聯，最終激活與減數分裂的相關蛋白或基因。
  6. Focal adhesion kinase tyrosine phosphorylation promotes rat hepatic fibrogenesis and its possible mechanism

    黏著斑激酶酪氨酸磷酸化促大鼠肝纖維化形成及其可能機制
  7. Objective : flt - 3 ligand ( fins - like tyrosine kinase receptor - 3 ligand, fl ) was a recently described growth factor affecting early hematopoietic progenitor cells, that play a key role in the growth and differentiation of primitive hematopoietic cells. fl promotes the survival, proliferation, and differentiation of hematopoietic progenitors in synergy with other growth factors

    Fms樣酪氨酸激酶受體3配體（ fms - liketyrosinekinasereceptor - 3ligand ， fl ）是一種新近發現的、能夠有效地刺激早期造血的細胞因子，可單獨或聯合其他細胞因子促進造血幹細胞的增殖。
  8. It is divided to extracellular and intracellular part by transmembrane domain. there are 13 n - glycosylation sites, 20 protein kinase c phosphorylation sites, 28 casein kinase ii phosphorylation sites, 4 tyrosine kinase phosphorylation sites and 15 n - myristoylation sites in the extracellular part of bt - r3 protein. an integrin recognition sequences rod lies in intracellular part of bt - r3 protein

    跨膜區域（ tmd ）將它分為胞內和胞外兩個部分，它的胞外有13個潛在的糖基化位點， 20個蛋白激酶c的磷酸化位點， 28個酪蛋白激酶的磷酸化位點， 4個酪氨酸酶的磷酸化位點， 15個豆蔻（十四烷基）酰化位點；它的胞內有1個整合蛋白（ integrin ）識別位點。
  9. Huangyal4 was complete nucleotide sequence of 1 854 bp with a nucleotide orf ( 1575 bp ), which encoded a protein consisting of 524 aa with molecular weight of 62. 2 kda and pi of 8. 96. strongly basic ( + ) amino acids, strongly acidic ( - ) amino acids, hydrophobic amino acids and polar amino acids of the protein were 13. 74 %, 11. 64 %, 36. 45 % and 22. 70 % respectively, and predicted secondary structure of the protein revealed many conserved domains such as n - glycosylation site, protein kinase c phosphorylation site, casein kinase ii phosphorylation site, n - myristoylation site, camp - and cgmp - dependent protein kinase phosphorylation site, tyrosine kinase phosphorylation site and a cytochrome p450 cysteine heme - iron ligand signature which was typical of cytochrome p450. a - helix and b - sheet of the protein is 47. 7 %, 45. 0 % respectively

    Huangya14 ）為材料分離克隆到一個細胞色素p450基因，命名為bccyp86mf5 ， cdna全長1854bp ，含1575bp的完整開放閱讀框，編碼524個氨基酸，其編碼蛋白質的分子量為61 . 2kda 、等電點為8 . 96 ；堿性氨基酸、酸性氨基酸、疏水氨基酸和極性氨基酸分別占總氨基酸的13 . 74 、 11 . 64 、 36 . 45和22 . 70 ；二級結構預測包括n -糖基化位點、依賴于camp和cgmp的蛋白激酶磷酸化位點、蛋白激酶c磷酸化位點、酪蛋白激酶磷酸化位點、酪氨基酸激酶磷酸化位點、 n -豆蔻酰化位點和細胞色素p450的典型區域，半胱氨酸亞鐵血紅素配體信號區等， -螺旋和-折疊分別佔47 . 7 、 45 . 0 ；與bccyp86mf1基因的氨基酸序列同源性達到95 . 2 ，與擬南芥cyp86c4的達到85 . 9 。
  10. Three - dimensional quantitative structure - activity relationship study of tyrosine kinase inhibitors

    酪氨酸激酶抑制劑的三維定量構效關系研究
  11. The progress in tyrosine kinase inhibitor has been reviewed, including the chemical structures and the pharmacophore models

    本文綜述了近年來酪氨酸激酶抑制劑的研究進展，包括抑制劑的結構和與激酶作用的藥效團模型。
  12. Gefitinib ( iressa, zd1839 ), a specific tyrosine kinase inhibitor that targets the epidermal growth factor receptor ( egfr ), is a novel molecular - targeting antineoplastic agent

    摘要吉非替尼是一種新型的分子靶向抗癌藥物，它選擇性抑製表皮生長因子受體酪氨酸激酶而發揮作用。
  13. Trka, the high affinity ngf receptor, contains an intracellular domain with tyrosine kinase activity and an extracellular domain with three tandem leucine - rich motifs flanked by two cysteine clusters in their amino termini and two immunoglobulin - like domains in the more membrane - proximal region

    膜外域含有8個亮氨酸的重復區域，其前後分別串聯著一組半胱氨酸殘基，緊挨細胞膜的是兩個c2 -型免疫球蛋白樣區ig和ig ；膜內域為酪氨酸激酶催化活性區。
  14. Expression of brain - derived neurotrophin factor and its receptor - tyrosine kinase receptor b in human ovary and their significance

    腦源性神經營養因子及其受體在人卵巢的表達與卵泡發育的關系
  15. Effect of gonadotropin on the expression of brain - derived neurotrophin factor and its receptor - tyrosine kinase receptor b in human ovary

    促性腺激素對人卵巢腦源性神經營養因子及其受體表達的影響
  16. Therefore, this project intend to explore mechanism of apoptosis mediated by protein tyrosine kinase ( ptk ) pathway by study of the role of erk1 / 2, jnk and p38 in apoptosis of u 2 - os cell line induced by bfgf

    本課題欲通過研究erk1 2 、 jnk 、 p38在bfgf誘導u2 - os細胞凋亡中的作用來探討酪氨酸蛋白激酶途徑參與細胞凋亡調控的作用機制。
  17. The key mechanisms involved are inhibition of protein - phosphotyrosine phosphatases and activation of nonreceptor protein - tyrosine kinases, in an insulin - receptor tyrosine kinase independent fashion

    釩在生物體內發揮作用的主要機制是通過蛋白磷酸酪氨酸磷酸酯酶的抑制和非受體蛋白酪氨酸的激活一種與胰島素受體完全不同的途徑發揮作用的。
  18. The neurotrophic and morphogenic activities of gdnf are mediated by its interaction with a multicomponent receptor complex formed by the ret receptor tyrosine kinase and a glycosylphosphatidylinositol ( gpi ) - anchored " accessory " receptor, gdnf family receptor alpha - 1 ( gfral )

    Gdnf的神經營養作用主要是通過兩類受體亞基介導，即膠質細胞源性神經營養因子受體alpha （ gfr s ）亞基和受體酪氨酸激酶ret亞基。
  19. Signal roles of protein tyrosine kinase in transforming growth factor - 1 or interferon - regulated proliferation and collagen synthesis by fibroblasts from hypertrophic scar and normal dermis

    內皮素對瘢痕成纖維細胞增殖和膠原合成作用的實驗研究
  20. Many regulatory factors involved in the process of proliferation and differentiation of trophoblast were examined. epidermal growth factor ( egf ) plays an important role in normal cellular growth and differentiation and acts on its placental target cells, i. e. the trophoblasts, via a specific receptor ( egfr ) which belongs to the tyrosine kinase receptor family

    表皮生長因子（ epidermalgrowthfactor ， egf ）是一種分佈廣泛，具有多種生物學效應的細胞因子，尤其對細胞的增殖具有強烈的促進作用， egf是通過與表皮生長因子受體（ epidermalgrowthfactorreceptor ， egfr ）結合發揮其生物學效應。
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