ubiquitin 中文意思是什麼

ubiquitin 解釋
遍在蛋白，泛素
  1. Phylogenetic analysis based on the amino acids of the ubiquitin / ribosomal fused proteins of different animals well reflected the established phylogeny of the chosen organisms, and amphioxus was branched off from chordates and formed a separate cluster with an intermediate placement between invertebrates and vertebrates in the tree

    通過對ubiquitin的系統進化分析，發現文昌魚ubf80除了具有脊椎動物和無脊椎動物的特徵外，還具有自己的一些獨特的特徵，從分子水平上支持了文昌魚是脊索動物進化過程中的一側枝的觀點。
  2. Whole mount in situ hybridization showed that amphihmgb transcripts were present ubiquitously in the early embryos from zygote to neurula, but they decreased gradually in mesoderm and endoderm and neural tube with development, and became restricted to epidermal cells in the hatched larva. it appear s that hmgb plays a role in the mitosis and differentiation of embryonic cells. another amphioxus cdna, amphiubf80, encoding ubiquitin / ribosomal fused protein s27a, was isolated from the gut cdna library of b. belcheri tsingtauense

    S004cdna序列編碼一個156個氨基酸殘基組成的蛋白質，與人的泛素蛋白ubf80具有較高的氨基酸序列同源性（ 145 / 156同源） ，且該蛋白具有泛素蛋白ubf80所共有的兩個結構域，即由72個氨基酸組成的泛素介導的蛋白降解結構域和由48個氨基酸組成的核糖體蛋白s27a結構域。
  3. We have identified in s. cerevisiae distinct ubiquitin - ligase complexes that define different erad pathways

    我們在酵母體內發現了一種參與不同erad途徑的特定的泛素連接酶復合體。
  4. This study demonstrated that the arabidopsis f - box protein coil associated with atcul1, atrbxl and skpl - like proteins askl and ask2 to assemble scfcoil ubiquitin ligase complexes. also, we found that the atcull component of scfcoil complexes contained two species including atcull and modified atcull. ( 2 ) we found that coil assembled to two separate scfcoil complexes with either askl or ask2 through immunoprecipitation analysis with plant expressing myc - tagged version of ask2

    用表達融合蛋白myc - ask2的擬南芥為材料，以- myc抗體進行免疫共沉澱分析發現， myc - ask2蛋白可以與coi1蛋白一起免疫共沉澱，但是不能與ask1蛋白免疫共沉澱，表明coi1蛋白與ask2蛋白，但是不能同時與ask1結合形成scf ~ （ coi1 ）復合體。
  5. We have known that ir may activate ubiquitin - proteasom pathyway, our experiments focus on whether ubiquitin - proteasome pathway involves in the regulation of p27klpl during ir responses

    我們知道ir能激活泛素化蛋白酶體途徑，那麼，泛素化蛋白酶體途徑是否參與ir誘導p27物』蛋白表達的調控
  6. The protein level of p21 increased lightly from 1 to3 h, then decreased at 6 - 9 h, reached maximum at 24 h after 2gy, it increased from 3 to 24 h exposed tology, and the protein level of p21 associated with cdk2 increased, which did not inhibit the cyclin e / cdk2 kinase activity, because of upregulation of cyclin e and deregulation of p27kipl after irradiation. in contrast to p21, p27kipl may be a key regulator of cyclin e / cdk2 activity in dna damage responses. hi the ubiquitin - proteasome pathway invovled in regulation of p27kiplexpression in response to ir the ubiquitin - proteasome pathway regulated selective and time - controlled elimination of p27 kipl

    與p27ki 」 ，表達水平不同， pzi蛋白表達水平在zgy照射后略有增加， 6一gh略有下降，在照后24h達到最大; 10gy照后1一3h開始增加，持續到24h ，並且cycline / cdkz復合物中pzi蛋白結合增多，但cycline / cdkz激酶活性並未受到抑制，除了因ir誘導cydine蛋白表達水平增加外，另一重要的原因就是與pzi同一家族的p27kip ，蛋白表達水平下降，失去了對cycline / cdkz的抑制活性。
  7. Ubiquitin - proteasome pathway and virus infection

    蛋白水解酶復合體通路與病毒侵染
  8. Both rad6 and ubcls are ubiquitin - conjugating enzymes, and mms2 is a ubc - like protein. radls and rad5 are both single strand binding ring linger proteins. rad6 binds to radls and mms2 - ubcls binds to rad5

    在泛素系統中起主要作用的是三種酶：泛素激活酶e1 ；泛素綴合酶e2 / ubc和泛素連接酶e3 。
  9. " for the discovery of ubiquitin - mediated protein degradation

    發現了泛素調解的蛋白質降解
  10. Construction and expression of recombinant eukaryotic expression plasmid of ubiquitin and epstein - barr virus nuclear antigen 1 fusion gene

    病毒核抗原1的融合表達載體的構建及表達
  11. In the 317 unigenes of 592 clones, 42 novel full - length genes and 90 novel testis - specific transcripts were obtained. they were deposited in the genbank. one of testis - specific transcripts, testis - specific calpastatin ( tcast ) and two novel full - length genes, nyd - sp27 and human ubiquitin - like fusion protein ( hufp ), were selected for study

    我們對其中的一個睪丸特異的轉錄本一鈣激活的中性蛋白酶古制物（ testi specificcalpastatintcast ） ，和兩個新的全長基因一nd七p27和人泛素樣融合蛋白山umanublqultln likeusionproteinhwp ）進行了進一步研究。
  12. The scfco, " ubiquitin - ligase complexes are required for jasmonate response in arabidopsis ( l ) arabidopsis coi is required for all the jasmonate - regulated response. it encodes a protein containing leucine - rich repeats and a degenerate f - box motif these structural features are characteristic of f - box proteins that function in ubiquitin ligase complexes for the ubiquitylation of substrate - proteins targeted for degradat1on

    以表達融合蛋白flag - coi1的擬南芥為材料，用- flag抗體進行免疫共沉澱分析發現， coi1蛋白可以與ask1 、 ask2 、 atrbx1和atcul1蛋白結合形成scf ~ （ coi1 ）復合體，並發現其中的atcul1蛋白包括未修飾和修飾的兩種形式。
  13. Effects of ubiquitin proteasome inhibitor induced endoplasmic reticulum stress and apoptosis on dopaminergic neuron

    泛素蛋白酶體抑制劑誘發多巴胺能神經元內質網應激反應及其凋亡的作用
  14. So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer

    泛素介導的蛋白質降解途徑的異常與許多疾病特別是腫瘤的發生密切相關。
  15. By sequencing random - selected clones from the library and using bioinformatics, 54 novel expressed sequence tags ( ests ) were obtained, in which there were 14 full - length cdnas, including peroxiredoxin gene, hmg - box gene, ubiquitin gene, signal recognition particle, acetyltransferase gene and lysozyme gene

    有14個克隆包含有完整的開放閱讀框，其中包括抗氧化物酶基因prx 、 dna結合蛋白基因、泛素基因、信號識別蛋白基因、溶菌酶基因和乙酰基轉移酶基因等具有重要生物學功能的基因。
  16. Nh2 terminus lacks a " destruction box " that controls the ubiquitin - dependent degration but contains an epithdermal growth factor receptor - like autophosphorylation sequence in addition to cyclin box. the structure hints that it is not only a cyclin in cell cycle regulation but also an intracelluar signal transducer molecule. cycg has not yet been matched with a cdk binding partner, and it ' s biologic function is still elusive

    G型蛋白是細胞周期蛋白家族中的新成員，它的分子結構與多數cyclin有所不同，其n端缺少降解所需的「 destructionbox 」氨基酸序列，而c末端卻包含有與表皮生長因子受體相似的自主磷酸化位點，這些表明它既是一種細胞周期蛋白，也是細胞內的信號傳導分子。
  17. The deduced n - terminal 76 amino acids of the protein were 100 % identical to those of abstract human and rat ubiquitin ( ub ), and the carboxyl extension protein ( cep ) sequences were also highly similar to those of the homologous proteins of human, rat and other species

    我們將這個cdna克隆命名為amphiubf80 。 089cdna序列編碼一個188個氨基酸殘基組成的蛋白質，與人aoeb166蛋白（ prxv ）的同源性達65 ，我們將這個cdna克隆命名為amphiprxv 。
  18. The results show that n - corl can also interact with another fragment f6 ( amino acids 2960 - 3576 ). further screening proteins that interact with anther fragment f6, we isolated the cdna of igm heaven chain contant region, ubiquitin - conjugating enzyme e2l6 and a new protein

    Ddevempmentbiology6第四軍醫大學碩士研究生論文它可以和a晶體球蛋白基因的啟動子區結合而命名，后又發現其同源物可見于果蠅，線蟲，小鼠，大鼠以及人類等。
  19. Advance in ubiquitin and ub - associated proteins encoded by viruses

    病毒編碼泛素及相關蛋白的研究進展
  20. Along with avram hershko and irwin rose, he was awarded the 2004 nobel prize in chemistry for the discovery of ubiquitin - mediated protein degradation

    他們突破性地發現了人類細胞如何控制某種蛋白質的過程，具體地說，就是人類細胞對無用蛋白質的"廢物處理"過程。
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