vaccine strain 中文意思是什麼
vaccine strain
解釋
疫苗株-
In recent years, the outbreak of nd appear some new characters, it is reported that the amount of immunity defeat on nd increased, even chicks with high hi titer can be infected by ndv virulent strain. the gene - engineering vaccine is badly needed to control nd outbreak. so newcastle disease virus strain b95, a naturally avirulent and heat stable strain, was introduced from australia
新城疫是國際獸疫局公布的16種烈性傳染病之一。近年來，新城疫的爆發出現了許多新特點，免疫失敗報道增多，甚至抗體水平較高的雞群也發病。為控制新城疫的爆發，急需研製基因工程苗。 -
Construction of attenuated salmonella typhimurium vaccine strain expressing helicobacter pylori catalase and observation on its protective immunity
基因減毒鼠傷寒沙門疫苗菌的構建 -
Hc ( hog cholera ), the virulent infectious disease caused by hcv ( hog cholera virus ), had been controlled effectively by hclv strain vaccine in the country
豬瘟是由豬瘟病毒引起的豬的一種病毒性傳染病。豬瘟兔化弱毒疫苗有效地控制了豬瘟在我國的急性發生和大流行。 -
Since the important roles of eo protein in the viral infection. immunity and virus - host interaction. the homology of 21 csfv strains was investigated by sequence analysis of eo genes in this study, which will provide some evidence for epidemiological study. in addition, the eo gene of hog cholera lapinized vaccine ( hclv ) strain was expressed in the prokaryotic and eucaryotic systems, and the recombinant proteins were preliminarily analyzed by immunological method
鑒于eo蛋白在病毒感染，誘導機體免疫及與宿主細胞相互關系中的作用，本研究克隆了2株豬瘟病毒eo基因並將其與其它毒株eo基因進行了序列分析，揭示了我國豬瘟病毒流行株之間的遺傳演化關系，為豬瘟病毒的流行病學研究提供依據。 -
Laboratory surveillance also found an increasing number of influenza virus detection recently. the predominant strain remains to be influenza a h1n1 new caledonia. the strain matches the vaccine strains recommended in the 2005 06 government influenza vaccination program givp
化驗結果顯示，近期偵測到的流感病毒的數字有所增加，經病毒分離檢測后發現病毒主要為甲型流感1 1新喀里多尼亞，與2005 06年政府流感疫苗注射計劃所使用的疫苗合。 -
Francis andre of smith kline - rit ( now glaxosmithkline biologicals ) in rixensart, belgium, and timo vesikari, a pediatrician at the university of tampere in finland, prepared and tested a vaccine derived from a rotavirus strain found in cows
比利時里森薩市史克藥廠（現為葛蘭素史克生物制藥）的安卓與芬蘭坦派勒大學的小兒科醫師維西卡里，以取自母牛的輪狀病毒品系制備疫苗，並進行人體試驗。 -
Rt - pcr was used to amplify the cdna of the genome. these cdna fragments were cloned into the plasmid pucm - t. the result indicated that the seguence of the genome was obtained. the genome of aev - nh937 composed of 7055 nucleotides, potentially encodes a polyprotein of 2134 amino acids. the genome of aev - nh937 has 94. 3 % nucleotides identity with the calnek vaccine strain of aev
把它們分段克隆在pucm - t載體上，經序列分析，獲得了aev - nh937毒株的基因組全序列及推導的氨基酸序列，基因組全長為7055個核苷酸，與calnek疫苗株具有94 . 3的同源性，編碼一個含2134個氨基酸的多聚蛋白。 -
The research consist of four parts. the first part is multiplication, purification and electron microscope examination of the avian encephalomyelitis virus. a 1 : 5 dilution of isolate - nh937 of aev and control group of pbs were inoculated to susceptible 6 - day - old chickens embryos. respectively. after incubation for 10 days, the urinay vesicle liquid was collected. making a comparison the size of the chickens embryos between the test group and the control group, the results showed that the size of the control group is bigger than that of the test group. purified virions were examined under the electron microscope, the result revealed that there are a lot of virions and the aev - nh937 was multiplicated in embryos. the second part was seguence analysis of the genome of the aev - nh937. nine pairs of primers were designed according to published calnek vaccine strain of aev
本研究共分四個部分：第一部分為aev的增殖，純化和電鏡觀察，用1 : 5倍稀釋的aev - nh937株和陰性對照pbs分別經卵黃囊接種於6dspf雞胚，繼續孵化10d后，收集尿囊液。比較接種組和健康對照組雞胚的大小，結果顯示，健康對照組雞胚明顯大於接種組。分離、提純aev ，把純化的病毒在電鏡下觀察，證明確有大量aev病毒粒子存在，說明aev在雞胚中成功擴增；第二部分是aev - nh937基因組的序列測定工作。 -
Sequence comparison indicated that the nucleotide homologies between the ha gene and those from eight other h3 subtype sfv isolates from china are over 95 %, and nucleotide identities between h3 sfv isolates in china and a typical h3 subtype avian influenza virus ( aiv ) strain dkuk1 - 63 are 95 % to 100 %. these might tell us that the ha gene of all h3 subtype sives isolated in china was originally from aiv although the vaccine based on ha do not protect against different subtype of influenza virus, it can provide favorable resistance to infection with antigenic variants within a subtype
通過與其它7株國內siv分離株和6株genebank中的h3流感病毒ha序列比較分析，結果表明分離自我國不同地區的8株h3siv核苷酸序列同源性均在95 %以上，且與禽流感病毒（ aiv ）經典代表株dkuk - 63序列同源性在95 - 100 %之間，證實我國h3sivha基因來源於禽的流感病毒。 -
Because of difficulty in differentiating eiav wild strain from the vaccine strain （ dla ） in vivo ， we have to build a fast identification method between wild strain and vaccine strain of eiav s2 is an accessory protein of equine infectious anemia virus ( eiav ), the s2 function is not fully defined
由於我國馬傳貧弱毒疫苗存在野毒和疫苗毒鑒別困難的問題，目前尚未得到歐美等發達國家的認證，如要進入國際市場，急需建立一種eiav強、弱毒快速鑒別診斷方法。 -
Construction of recombinant fowlpox virus coexpressing aiv ha and ndv f. for the construction of transfer vector pfgs11haf, aiv ha gene of f strain in puc18ha and ndv f gene of f48e8 strain in puc19f were removed and inserted into pfgs11. recombinant fowlpox viruses ( rfpv ) coexpressing aiv ha gene and ndv f gene were constructed by using different promoters of ps and pe / l. recombinant rfpvs were derived by dosper liposome - mediated transfection with the two transfer vectors on chicken embryo fibroblast ( cef ) monolayer cultures which were infected by wild type fpv chinese vaccine strain 282e4 3 - 4 hours earlier
Puc18ha和sk質粒同時經hind 、 kpn酶切后連接得中間質粒skha ；將質粒skha用bamhi酶切回收ha基因插入到插入載體pfgs11中的bamhi位點，通過酶切鑒定獲得了pfgs11ha ；將含ndvf基因的質粒puc19f用hind 、 sal酶切經klenow酶補平插入到經sma酶切后的skifn中pe / l啟動子下獲得中間質粒skf ，再將質粒skf和puc18質粒先分別用ecor 、 xho酶切klenow補平，后再共同用sac酶切連接得puc18pelf ， sal酶切回收pe / l - f基因盒插入到pfgs11ha的sal位點，通過酶切鑒定獲得了pe / l - f與ps - ha同向的表達載體pfgs11haf 。 -
Construction of an attenuated salmonella typhimurium vaccine strain carrying helicobacter pylori hpaa gene
亞單位基因重組活減毒鼠傷寒沙門疫苗菌的構建和鑒定 -
Construction and identification of recombinant attenuated salmonella typhimurium vaccine strain expressing helicobacter pylori urease subunit b
重組減毒鼠傷寒沙門氏菌的構建和鑒定 -
Construction and identification of a recombinant attenuated salmonella typhimurium vaccine strain expressing helicobacter pylori hpaa gene
亞單位的重組減毒鼠傷寒沙門菌核酸疫苗的構建 -
Establishment of an attenuated salmonella typhimurium vaccine strain sl3261 expressing hp - nap gene
表達幽門螺桿菌過氧化氫酶的減毒沙門氏菌疫苗株的構建及其免疫保護作用的觀察 -
Or it could be just that the vaccine strain “ is in the optimal antigen - presenting cells to begin with, ” he says, thereby accounting for the powerful immune response
不然就是這個用來做為疫苗的菌株非常適合刺激抗原呈現細胞來啟動免疫反應，所以能引發很強的免疫反應。 -
The result shows that the high degree of homology of e2 sequences and 426 residues amino acid sequences existed in the strain hclv, hcv - jn, hcv - yc, fc and the epitopes between the four strains are not variable obviously by analysising the variation of some main amino acid residues substitutions of e2 major antigenic domains, confirming initially immunization with hcv vaccine strain can resist challenging of field strains
結果發現， hclv與fc間核苷酸及氨基酸序列的同源性分別為98 . 3 、 99 . 2 ；兩個野毒株與hclv和fc株之間的同源性也分別在98以上，與alfort株的同源性最低，分別在83 、 89左右。據此，可推測hclv 、豬瘟野毒株和c株之間的e2基因序列及氨基酸序列無明顯差異。 -
Both should be an “ intermediate ” vaccine strain of ibd and should preferably be administered in the drinking water
兩次免疫都應使用中等毒力的ibd疫苗毒株，並且最好採用飲水進行免疫。 -
Furthermore, the study also firstly found that mukteswar, a widely used vaccine strain in china, was classified into genotype vii
此外，本研究還首次對我國常用的中發型疫苗毒株1系（ mukteswar株）進行了基因分型，結果發現也屬于基因型vll 。 -
The result further proposed that different genotypes of ndv had not directed the antigenic changes of f protein, the most important protein of ndv in the protective immune response of the fowls. protective efficacy difference among various genotype ndv vaccines of different origin was studied. except the vaccine strain lasota ( genotype ii ), the challenge strain f48e8 in china, the ndv strains tested were isolated from nd outbreaks in chickens, gooses, and pigeons
通過不同來源不同基因型（亞型） ndv滅活苗與常規疫苗（包括lasota弱毒活疫苗和滅活疫苗）的免疫保護效力的比較，證實了所有疫苗均能激發機體產生抗不同基因型ndv的抵抗力， hl抗體變化都具有一個抗體滴度迅速上升的過程，動態特徵除lasota弱毒活疫苗組有些不同外相當一致。
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