virion 中文意思是什麼

virion 解釋
n. 名詞 【醫學】病毒顆粒。

  1. Avian encephalomyelitis virus ( aev ) is a picornavirus with a predilection for the central nervous system and other parenchymous organs of chickens that is transmited by the oral - faecal route. the virus may be spread by the vertical and horizontalroutes, and because of its great stability, contaminated areas may remain infectious for long periods. the egg - adapted van roekel strain is highly neurotropic and does not grow efficiently in the enteric tract of the chicken, and the field isolates of aev is usually enterotropic. despite this. the virion polypeptides of both naturally - occurring strains and the van roekel strain are antigenically identical

    侵害雞的中樞神經系統和其它實質性器官，該病毒通過口-糞途徑傳播，具有水平和垂直傳播的能力。由於它極大的穩定性，被污染的區域可能長期保持傳染性。雞胚適應株vanroekel是高度嗜神經的，並且在雞的腸道內不能有效的生長，而野毒株卻是嗜腸道型的。
  2. A virion consists of a protein coat surrounding one or more strands of dna or rna

    一個病毒粒子包括外部的蛋白衣殼和內部的一條至多條dna或rna鏈。
  3. Phage display describes a selection technique in which a peptide or protein is expressed as a fussion with a coat protein of bacteriophage, resulting in display of the fused protein on the surface of the virion, while the dna encoding the fussion resides within the virion

    自1985年gpsmith首次提出噬菌體展示技術以來，隨著生物技術的發展，噬菌體隨機肽庫已成為研究分子間相互作用的有力工具，特別是在抗原表位研究方面。
  4. At first, 1. 67 u g per well mcab all was coated on three wells of a plate, and then 1. 5 x 1011 phage virion was diluted and added, after incubating with the target, wash away unbound phage by tbst ( 0. 1 % tween - 20 ), the bound phage was eluted with ph 2. 2 tris - gly buffer and amplified, the specially bound phage was enriched by taking through addition binding / amplification cycles. ln the following cycles, the stringency of panning can be increased by raising the concentration of tbst or decreasing that of mcab all, collecting and titering the washing phage of last time and output phage in each round, the selective ratio and the false positive rate of each round were worked out, the gradually increasing of selective ratio and decreasing of positive rate shows that the panning was effective. after 4 rounds of panning, 11 phage clones were selected after competitive - ellsa, the dna samples of 8 positive clones and 1 negative clone were sequenced and all the foreign peptides inserted was also deduced, a clear consensus binding sequence emerged

    在本實驗中，利用隨機12肽庫對抗豬瘟病毒（ classicalswinefeverviruscsfv ）糖蛋白me2的單抗a11進行表位篩選，經過四輪篩選以後，隨機挑取11個克隆作競爭- elisa檢測，結果表明，所挑11個克隆中，有9個克隆能對me2蛋白和a11反應產生抑制作用，抑制率最高可達64 ； dna測序以後經過dnastar軟體分析，發現它們的核心序列為anwralsl ，該核心序列與豬瘟病毒e2蛋白的28 - 35位氨基酸ttwkeysh具有同源性；夾心- elisa檢測和western - blotting試驗均證明所挑陽性克隆能被a11所識別；人工合成含核心序列的多肽經間接elisa試驗證實，也能被a11識別。
  5. In young chickens aev induces paralysis, ataxia and muscular dystrophy, while in older chickens, infection is usually subclinical, resulting in a decline in egg production and hatchability. infectivity was shown to remain unaffected by chloroform, low ph, pepsin, trypsin and deoxyribonuclease. magnesium cations were shown to stabilise preparations of the virus against heat inactivation. the buoyant density of virions are 1. 31g / ml. the diameter of the virion was estimated to be 22 to 30nm. the aev can be adapted to grow in chicken embryo. the inability of aev to grow effeciently in most cell cultures

    幼雞感染該病毒后，引起麻痹、頭頸震顫甚至共濟失調，而成雞常呈亞臨床感染或導致產蛋量和孵化率下降。病毒的感染性不受氯仿、低ph 、胃蛋白酶、胰酶和脫氧核糖核酸酶的影響，鎂離子可增強病毒對熱的穩定性，病毒的浮密度為1 . 31g ml ，直徑為22 - 30nm ，該病毒主要在雞胚中增殖，在大多數細胞培養物中不生長。
  6. Prevention and cure of the derzsy ' s disease depended on vaccine and antiserum, antibodies of eggs. the vaccines includes goose embryo and duck embryo vaccines which were used 1n breed goose and goslings, and those vaccines have great effect in breeding goose, but the entire virion live vaccines and attenuated vaccines exist many deficiencies. such as preclinical infection, dissemination of virus, recovery of viru5, etc. those proplems can be sol / ed by producing genetic engineering " asclne

    目前使用的疫苗分為種鵝用和雛鵝用的鵝胚和鴨胚化疫苗，這些疫苗在實際生產中發揮巨大作用，因其為全毒苗或弱毒苗，存在著潛伏感染，排毒散毒，毒力返祖的缺陷，基因工程疫苗的研製可解決上述問題。
  7. Nevertheless, the immune system and viruses have substantially evolved together and viruses demonstrate many stratiges for subverting immune response. for enveloped virus, for instance hiv and eev can incorporate host rca into their envelope by budding through the plasma membrane, and these protect the virion against host complement attack

    遺憾的是，一些有包膜的病毒也在長期的演化過程中獲得了補體系統的這種自我保護機制，即可以通過結合宿主膜補體調節蛋白來逃避補體的攻擊。
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