弱抗原 的英文怎麼說
中文拼音 [ruòkàngyuán]
弱抗原
英文
poor antigen-
Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸蟲病疫苗研究已有60多年的歷史，大致經歷了死疫苗、活疫苗（照射致弱尾蚴疫苗）和基因工程疫苗等研究階段，產生了一些who / tdr推薦認為很有希望的疫苗候選分子，如谷胱甘肽- s -轉移酶（ gst ） 、副肌球蛋白（ sm97 ） 、照射致弱疫苗抗原5 （ irv - 5 ） 、磷酸丙糖異構酶（ tpi ） 、曼氏血吸蟲膜內在蛋白（ sm23 ）和脂肪酸結合蛋白（ fabp ， sm14 ）等，但其對宿主的保護作用均不甚理想，未能穩定地達到40或以上的保護力水平，因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑，進一步提高其保護力。Plant protection in greenhouse from foliar blight by the endophyte was clearly in the early stage after inoculation with rhi. solani ciat 6780. but the resistance became weak as time went on
旗草體內抗病試驗表明，內生菌感染的植株對葉枯病具有抗性，但這種抗性隨著病原菌（ rhizoctoniasolani ）的擴展而減弱。Facs results showed that umbilical cord blood mscs did not express antigens cd34, cdlla and cdllb, and expressed cd29 and cd71, which was identical to that of human bone marrow - derived mscs
用流式細胞儀檢測msc的表面標志結果顯示，臍帶血msc不表達cd34 、 cd11a和cd11b ，強表達cd29 ，弱表達cd71 ，與骨髓msc表面抗原特性一致。The quantity and quality of hematoblast in umbilical cord blood ( ucb ) can be compared with bone marrow. furthermore, it has other advantages : widely sourced, no contamination of pathogeny, weakly antigenicity, and no mature lymphocyte, et al
臍血中造血細胞的數量和質量都與骨髓相近，而且，具有來源豐富、無病原體污染、抗原性弱、淋巴細胞不成熟等優點。Sichuan lands in the west of our country, pass through for the west of our country, expressway general development is stated, reach the west china traffic major problem of building existence : traffic facility amount serious is below, density passes low, traffic demand product is exceptional ; traffic facility overall quality is low ; technical standard is not high ; traffic facility disease is serious ; it is weak to fight calamity ability ; traffic structuralness contradictory very outstanding, big medium or small proportion structure is not reasonable ; traffic technical structure is not enough perfected ; traffic regional structure do not let reasonable etc.
四川地處我國西部，通過對我國西部高速公路發展的概述，得出了西部交通建設存在的主要問題:交通設施總量嚴重不足，密度過低;交通需求缺口過大;交通設施總體質量過低，技術標準不高;交通設施病害嚴重，抗災能力薄弱;交通結構性矛盾十分突出，大中小型比例結構不合理;交通技術結構不夠完善;交通區域結構不盡合理等。造成這些現象的原因何在，筆者從我國近年來公路建設的政策背景出發，得出的結論主要是建設資金缺口過大。那麼，四川省高速公路建設中存在的問題又是什麼Results : the expression of pcna and fibronectin in placenta of 30 patients with early abortion was significantly reduced ( p < 0. 05 )
結果：早期自然流產患者較正常早期妊娠胎盤中增殖細胞核抗原、纖粘連蛋白的表達減弱（ p < 0 . 05 ） 。The results showed the technique suit either completely to immunohistochemical study of the pulp matrix and of the cell surface expression that was weaker antigenicity, or to enzyme histochemical staining of the dental pulp
結果表明，它完全滿足牙髓基質和抗原性較弱的細胞表面標志等成分的免疫組化染色，同時也適用於牙髓的酶組織化學染色。The result showed vp2 hydrophilic region and antigen variant and virulence of ibdv had very affinity
該結果表明， vp2與ibdv毒株的毒力強弱和抗原變異有密切的關系。We educed the principal factors that led the young seedling of lilium tsingtauense population to die were imputed to the serious drought during l ~ 2years old, and the deficiency of soiar light in the communities, as well as in weaker intrinsic resistance to unthvorable environmental conditions
環境篩分析得出，導致青島百合種群幼齡個體死亡的內在原因是其較弱的抗逆性和適應能力，外在原因是嚴重的乾旱和水澇、群落內的光照不足及外界干擾。The reason is that, first, from the very beginning the enemy ' s strength and our weakness have been relative and not absolute, and that, second, our efforts in persevering in the war of resistance and in the united front have further accentuated this relativeness
因為一則敵強我弱之原來狀況就是相對的，不是絕對的；二則由於我之堅持抗戰和堅持統一戰線的努力，更加造成這種相對的形勢。The main works are listed as follows : ( 1 ) the small capacitance measuring circuit for ect based on the charge amplification principle was deeply analyzed and improved. the stray - immunity and the charge injection effect of this circuit were deeply analyzed. the influence of the charge injection effect was eliminated by practical time sequences and circuit structure differential
本文的主要工作和創新點如下： （ 1 ）對基於電荷放大原理的微弱電容測量電路進行了深入的分析和改進，深入分析了該電路的抗雜散電容性能及電荷注入效應問題，通過時序的合理設計消除了電荷注入效應等因素對測量結果的影響，改進了該電路的數學模型。At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。A protein substance produced in the blood or tissues in response to a specific antigen, such as a bacterium or a toxin. antibodies destroy or weaken bacteria and neutralize organic poisons, thus forming the basis of immunity
抗體，免疫體血液或組織針對某種抗原如細菌或毒素而產生的蛋白質物質。抗體消滅細菌或削弱其作用，中和有機毒素，因而形成免疫力The expression conditions of e2 gene in p. pastoris were optimized, the results indicated that the peak obtained after 72 hours ; pattern of inhibition / induction could improve expression level ; the best ph value were between 7. 5 and 8. 0 and the optimized methanol - induced concentration was 2 % - 3 % the e2 genes of the prevalent strain ( guangxi yulin strain ) and c strain derived from rabbit spleen tissue were amplified and cloned into e. coli the expression vector pproex - htb respectively, the recombinant plasmids pproex - gxyl and pproex - c were obtained and then were transformed into the dh5a e. coli competent bacteria respectively, the recombinant bacteria could express the major antigen region of e2 gene, the expression yields amount to 35 % and 38 % repectively
豬瘟病毒ez基因的原核表達： pcr擴增出當前豬瘟流行野毒株，中國豬瘟兔化弱毒（ c株）兔脾組織毒ez基因的主要抗原區，將其克隆到原核大腸桿菌表達載體pproex htb中誘導表達，經sds page檢測表明，重組質粒能表達ez基因主要區蛋白， westernblot檢測表明，誘導表達蛋白與豬瘟陽性血清發生特異性反應，表達量為35和38 ，可用於基因工程診斷抗原。The study is mainly about finding the reason that caused atypical hc through analysis and homology comparison on e2 gene sequences and amino acid sequences of e2 glycoprotein among strains hclv, fc, hcv - jn, hcv - yc, shimen et. al. at last, the best program against hc was established in order to control and erase hc
本研究主要是對豬瘟兔化弱毒疫苗、豬瘟病毒野毒株抗原基因（ e2 ）進行序列分析和同源性比較，分析發生非典型性豬瘟的原因，並在此基礎上制定最佳豬瘟免疫程序。A few years latter the research showed, vp2 hydrophilic region and antigen variant and virulence of ibdv had very affinity. in order to lucubrate difference of virulence and antigen, and validate correntness of sequencing result, the test adopted sandwich enzyme - liked immunosorbent assay ( elisa ) and antigen caprure - elisa to determine virulence and antigen. and validate correntness of above - mentioned result
而近幾年的研究表明， vp2高變區與ibdv的抗原變異和毒力強弱有密切的關系，為進一步了解強弱毒株毒力和抗原的差別，並進一步證實測序結果的正確性，本試驗採用雙抗夾心elisa和ac - elisa的方法分別對其毒力和抗原進行了測定，並通過動物試驗證實了，其結果與序列分析結果基本一致。The cfrc sample is always ruptured in the place where materials weakly resist outside force, and because the cracks " or damages " distribution of cfrc is random, bending strength of cfrc takes on dispersed
本文最後採用weibull統計理論對裂紋鈍化后的cfrc的抗彎強度進行了評價，通過最弱環原理解釋了weibull模數的力學意義以及它與cfrc材料中裂紋的關系。Research has shown that these causative factors can weaken both digestion as well as the protective defenses in our gi tract and lungs allowing for allergens to more easily confront our beleaguered immune system
研究結果顯示這些造成過敏的因素可能同時削弱消化功能以及腸胃道和肺部的防禦能力，讓抗原更容易入侵受困的免疫系統。Cd 14 * monocytes or bone marrow derived hematopoietic progenitor cells cultured with granulocyte - macrophage colony - stimulating factor ( gm - csf ) and il - 4 differentiate into efficient apc with morphology and cell surface molecule expression typical of immature dc. it was demonstrated that a variety of factors ( such as lps, tnf - a, il - 1, monocyte - conditioned medium, and cd40 receptor cross - linking ) induce the maturation of immature dc to mature dc that are much more potent in activating t cells by increasing the expression of costimulatory molecules and cytokines, promoting the migration of dc to draining lymph nodes, and down - regulating the capacity of dc to capture and process antigen
在體外，外周血cd14 ~ +單核細胞和cd34 ~ +骨髓造血前體細胞在粒細胞-巨噬細胞集落刺激因子（ granulocyte - macrophagecolony - stimulatingfactor ， gm - csf ）和il - 4的共同作用下可分化為未成熟dc ，未成熟dc具有強大的攝取和處理抗原的能力，但其抗原提呈能力較弱；未成熟dc在炎性細胞因浙江大竿俗士學位論文潛廷平子汐ilq ， yfax病原成分汐lpsx單核細胞條件培養液或cd40l等作用下可分化為成熟dc 。A surface antigen hemagglutinin - neuraminidase ( hn ) gene of the ndv b95 strain, was selected to study as target gene. referred to the reported sequence, rwo primers were designed and synthesized. hn gene of ndv b95 strain was amplified by rt - pcr, the pcr products were checked by agrose gel electrophoresis and purified by agrose gel fraction method
為此，從澳大利亞某大學獸醫病理系引進一株ndv熱穩定性天然弱毒b95株，並選取其表面抗原血凝素?神經氨酸酶的編碼基因為目的基因，根據國外已發表的序列，設計一對引物，利用rt - pcr技術擴增出了ndvb95株hn基因。分享友人