核磷蛋白 的英文怎麼說
中文拼音 [hélīndànbái]
核磷蛋白
英文
nuclear phosphoprotein-
At rest, the heterodimeric rel / nf - k b complex is located in the cytoplasm bound to an inhibitory factor, i k b. upon stimulation, i k b is phosphorylated and degraded, free nf - k b then translocates into the nucleus where it binds to k b site to regulate transcription
靜息時, re皿4bh聚體與抑制蛋白kbs結合,在細胞漿中保持無活性。受到刺激, ikb分子迅速磷酸化並降解,釋放nf兒b轉位入核,通過與kb位點結合調節轉錄。The changing tendencies of the relative contents of phosphorous contained substances have been detected by in - vivo " p magnetic resonance spectroscopy ( in - vivo " p mrs ) during the whole hatching process. in - vivo ] p mrs proved the catabolism of adenosine 5 ' - triphosphate ( atp ), phosphorous ester and phosphocreatine ( pcr ) when the embryo dead. the results could be used to deduce the conversion of phosphorous contained metabolites during the chicken embryo developed
用活體核磁共振定域氫譜( in - vivohmagneticresonancespectroscopy , in - vivohmrs )對胚胎發育過程中羊水和蛋白、蛋黃的成分進行了分析;用活體磷譜( in - vivo 』 』 pmrs )的方法分析了在整個胚胎發育過程中含磷代謝物的相對含量隨時間的變化,表明了磷脂類物質及三磷酸腺苷( atp ) 、磷酸肌酸( pcr )在此過程中的變化及可能的相互轉化的趨勢,胚胎死亡后的磷譜也證明了磷脂類物質及三磷酸腺苷( atp ) 、磷酸肌酸( pcr )在死亡過程中降解為無機磷的現象。Rich in protein, phosphorus, potassium, riboflavin and vitamin a and d
含豐富蛋白質、磷、鉀、核黃素及維他命a和d 。Histidine a basic amino acid formed only rarely in proteins. it is formed from atp and 5 - phosphoribosyl pyrophosphate in a complex biosynthetic pathway. glutamate is an intermediate in its breakdown
組氨酸:是蛋白質中少有的一種堿性氨基酸。由atp和5 -磷酸核糖基焦磷酸鹽通過復雜的生物合成途徑合成。在其降解過程中可形成谷氨酸。Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后,就與ajs發生解離而游離到細胞漿中,此時細胞的粘附功能也發生障礙,游離到胞漿中的-連環蛋白,一部分被抑癌因子apc降解,一部分則轉移到細胞核內,與核內的轉錄因子tcf lef結合,啟動與細胞增殖有關的基因轉錄。There were strong stat3 immunostaining in the glandular epithelium and weak nuclear translocation of tyrosine - phosphorylated stat3 in the luminal epithelium containing a blastocyst in the day 4 morning
第4天上午子宮腺上皮中的stat3免疫染色較強,且在胚泡所在處的的子宮腔上皮中有弱的酪氨酸磷酸化stat3蛋白的核轉位。And the intron had a lot of gt repeated sequence. the dna and protein sequence of this gene was analyzed using the bioinformatics tools. two functional domains were found in the protein
運用生物信息學手段對3一磷酸甘油脫氫酶基因核酸以及蛋白質序列做出了分析,發現這個基因編碼兩種功能的結構域,磷酸化酶結構域和3一磷酸甘油脫氫酶結構域。There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose
表皮生長因子( egf )能使p120 ~ ( ctn )酪氨酸磷酸化,磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強; p120 ~ ( ctn )在細胞內的分佈出現明顯的核內轉位, -連環蛋白也出現相似的變化。Especially, apoptin is partially similar with ribonucleotide reductase, uridylate kinase and phosphotriesterase in the amino acid sequence. the similarity between them indicates that apoptin maybe takes part in the signal pathway of apoptosis with phosphotriesterase activity or operates on hnrna with ribonucleotide reductase or uridylate kinase activity
凋亡素與它們的長序列相似性表明,它可能具有磷脂酶活性,在細胞信號通路中起作用;或者具有核糖核苦酸還原酶和尿苦酸激酶活性而對hnrna發揮作用;或者是與其中具有某種活性的蛋白質存在競爭性抑制作用。It has been shown that domain ia is responsible for cell recognition, domain ii is to be involved in translocation of the toxin across membranes, and domain hi catalyzes the adp - ribosylation of elongation factor2, which arrests protein synthesis and results in cell death
人組蛋白h3是堿性核蛋白,富含精氨酸,在生理條件下, h3的精氨酸帶正電荷,而dna的磷酸基團帶負電荷,所以組蛋白和dna分子主要依靠靜電引力相結合。Many cell signal transduction pathways have been discovered in the regulation of apoptotic induction and reduction. mito - gen - activated protein kinase ( mapk ) is a group of particular ser / thr protein kinases which are activated when its conservative thr and tyr residues are both phosphorylated by upstream mapk kinases
絲裂原活化蛋白激酶( mapk )是一群特殊的絲蘇氨酸蛋白激酶,它通過其上游mapkk使其保守的蘇氨酸和酪氨酸殘基雙磷酸化而活化,活化的mapk可轉移到核內,參與基因表達調控。24, 48, 72 hours later after transfection, we testified the expression of pp38 with mab h19, and pp24 with the antiserurn of pp24 expressed in e. coli. the tests justified the expression of pp24 in prokaryotic and eukaryotic expressing systems. in order to study the correlation of pp38 and pp24, we cloned pp38 gene and pp24 gene into pbudce4
為研究pp38和pp24之間的關系,將型mdvmd11株的pp38基因和pp24基因的完整orf克隆到真核雙表達載體pbudce4 . 1中,轉染cef后,通過ifa檢測和用抗pp24多克隆血清進行western - blotting試驗檢測到了pp38和pp24磷蛋白的共表達。Ebv gp350 and c3d bind selectively to the same site on the cr2, epitopes on scr - 1 and scr - 2 are necessary for the binding. as soon as c3d binds to scr - 1 and scr - 2, cr2 may cross - link - 8 - to memberane ig and form a " co - capping " structure, moreover, activate b lymphocyte through cd19, a component of cd19 / cd21 / cd81 / leul3 complex, signaling and / or nucleolin tyrosine phosphorylation independent on cd 19 signaling pathway
配體與scr l和scr 2結合后, crz與細胞膜免疫球蛋白( inlg )形成「共帽」 kofthofcccptor )結構,並經過d19c 21兒81肚u13復合體中d19的信號轉導以及不依賴于cd途徑的核仁素( nucleolin )酪氨酸磷酸化激活b細胞。To make clear the hypothesis, a middle cerebral artery occlusion ( mcao ) and hypoxia and glucose - deprivation ( hgd ) ischemic models were used in in vivo and in vitro study, respectively. we first studied the cellular localization of kvl. 2 and the co - localization of kvl. 2 protein and vegf receptors flk - 1 and flt - 1, observed the effect of mcao on kvl. 2 expression and phosphrylation in the rat brain in vivo, then investigated the effect of vegf on ischemia / hypoxia cell damage and tyrosine phosphorylation of kvl. 2 in sh - sy5y cells. finally, in order to further elucidate the relationship between vegf ' s neuroprotection and its regulation on kvl. 2 phosphorylation, we used a specific antisense oligodeoxynucleotide ( odn ) to knockdown the expression of endogenous vegf to observe its role in ischemia / hypoxia cell damage and regulation of kvl. 2 phosphorylation
為了驗證上述假設,本文分別在整體和離體水平,採用大腦中動脈缺血( middlecerebralarteryocclusion , mcao )和體外氧?糖剝奪( hypoxiaandglucose - deprivation , hgd )缺血模型,首先了解了kv1 . 2蛋白的細胞定位及與vegf受體flk - 1和flt - 1的共存情況,觀察了整體mcao后缺血再灌不同時間大鼠腦內kv1 . 2蛋白的磷酸化水平變化,然後通過外源性給予vegf蛋白,在sh - sy5y細胞株上觀察其對缺血細胞存活率及kv1 . 2蛋白磷酸化水平的影響,最後利用vegf反義脫氧寡核苷酸( oligodeoxynucleotide , odn )特異阻斷內源性vegf蛋白的表達,觀察內源性vegf蛋白在缺血細胞損傷及調節kv1 . 2蛋白磷酸化中的作用,以進一步明確vegf缺血保護效應與其調節kv1 . 2蛋白磷酸化之間的關系。“ langyatai ” brand cider has rich nutrition, such as ca2 +, p3 +, k +, fe2 +, lactochrome and nicotinic acid etc. and all kinds of vitamin being beneficial to body, all above are creamed from apple, meanwhile, after low - temperature fermentation, some organic nutrition of low sugar and high protein are produced, including malic acid, butanedioic acid, tartaric acid, seventeen amino acid and high powerful, high nutritional alcohol ester etc
瑯琊臺蘋果酒營養豐富,提煉了蘋果的主要精華,如蘋果中的鈣、磷、鐵、鉀、核黃素和尼可酸等二十多種微量元素,以及各種對人體有益的維生素.同時經過低溫生化發酵,生成了低糖類高蛋白等各種有機營養物質,如蘋果酸,琥珀酸,酒石酸及17種氨基酸和高能量高營養的醇酯等。分享友人