氫化皮質素 的英文怎麼說
中文拼音 [qīnghuàpízhísù]
氫化皮質素
英文
ala-cort-
The 11 - hsd1 expression in the fetal brain also gradually increases with gestational age at late gestation and continues to increase in the hippocampus after birth until the 15th postnatal day, which shows a pattern very similar to th secretion. furthermore, previous data show injection of thyroxine ( t4 ) to normal newborn rats up - regulates gr expression in the hippocampus. these data suggest that the role of th in neural development may be partially ( if not all ) accomplished through regulating gc ' s activity
在海馬結構， 11 - hsd1與gr共存於同一海馬神經元內，主要呈現還原酶的特性，能使無活性的11 -脫氫皮質酮（ a ）可的松（ e ）轉化為有活性的皮質酮（ b ）皮質醇（ f ） ，從而提高組織局部的糖皮質激素濃度，這樣， 11 - hsd1的存在就為親和力較低的gr發揮作用提供了前提條件。Which may provide the molecular basis for the inberine regulation of ll p - hsdl expression by glucocorticoids. secondiy, the regulation of l l 9 - hsdl expression and redutase activity by glucocorticoids was investigated in the primny cultured human chorionic trophoblast
整個妊娠過程中胎盤11 - hsd活性以氧化酶為主，使母體gc在進入胎兒循環前大部分被轉化為無活性的17 -羥- 11 -脫氫皮質酮，保證胎兒正常發育所需的激素濃度。
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