激酶類 的英文怎麼說
中文拼音 [jīlèi]
激酶類
英文
protein kinases-
I suggested a radically new approach : augmenting humans ' natural catabolic machinery with microbial enzymes
我提出過一種激進的新途徑:用微生物酶來加強人類天然降解機構。Progress on human glandular kallikreina
人類腺體激肽釋放酶2的研究進展A homolog of ga sbeta - hydroxylase gene expression pattern was examined. hybridization signals of this gene could be detected at day 5 and however, they appear again after day 10 when explants cultured with hormones. it has the similar pattern when the explants cultured without hormones or uncultured
風信子ga羥基化酶類似基回在外植體表達,在含有外源撒素條件下培養的前5天受到激素的抑制而幾乎不表達,第10天開始在花分生組織中表達。Chloroplast phosphoprotein were first found in thylakoid membranes by bennett o the attachment or removal of a phosphate group from a protein may have profound effects on that protein ' s activities and properties, the reversible phospharylation of the membrane protein in thykaloid is a dymanic equilibrium process
而bennett ( 1977 )發現的類囊體膜蛋白可逆磷酸化已成為近年研究的熱點之一,蛋白質連上或是移去磷酸基團都將強烈影響蛋白質的生理活性和性質,這需要類囊體膜蛋白激酶和磷酸酯酶的參與。Calcium dependent protein kinases ( cdpks ) are a kind of serine / threonine protein kinases that are only present in plants and some protests
鈣依賴蛋白激酶( cdpks )是一類僅在植物和部分原生生物中存在的絲氨酸蘇氨酸蛋白激酶。That shows there are some difference in the steroid regulation between the anuras and the urodeles. among three of the steroid, one can convert to the other, and some enzyme activity is concerned with the conversion
三種類固醇激素存在相互轉化的關系,睪酮可能在雌二醇和孕酮的轉化中起著底物的作用,這種轉化與某種芳香化酶的活性有關。Northern blot results show that nos. 66 - 1, 84, 89 - 1, 97, 108, 152, 175 and 233 have stronger signal in sp6 - tester than in sp6 - driver ; and no. 23 has weak signal only in sp6 - tester, nos. 94, 165, 172, 185 and 191 have similar hybridization signals in both sp6 - tester and sp6 - driver ; nos. 4, 17, 18, 28, 6 9, 101, 156 - 1, 157 - 1 and 183 do not reveal hybridization signals in both sp6 - tester and sp6 - driver ; the results of sequencing and blastn and blastx on ncbi indicate that no. 23 cdna ( 846bp ) has significant alignments with nicotiana tabacum mrna for elicitor inducible beta - 1 - glucanase nt - sube76, and arabidopsis thaliana clone 7119 for glycosyl hydrolase family 17 ( protein id : at5g55180. 1, supported by cdna : 7119, supported by cdna : gi _ l 87001 54 ) and arabidopsis thaliana beta - 1 - glucanase - like protein ( gi _ 2 1594590 ) ; no. 84 cdna ( 560bp ) has significant alignment with lotus corniculatus aspartate aminotransferase mrna ( complete cds length = 1685, gi | 2605931 | gb | af029898. 1 | af029898 ) for aspartate aminotransferase ; no. 89 - 1 cdna has significant alignment with arabidopsis tha
與同源性最高的擬南芥類似晚期胚胎發生高豐度蛋白比較,二者都具有lea 2結構域、保守分泌蛋白cog5608結構域和低復雜度區,都具有pkc磷酸化位點、酪蛋白激酶磷酸化位點、 n十四酞化位點和酚胺化位點,所不同的是: ( )在結構功能域上, 152全長cdna編碼的蛋白質序列中多了1個lea 2結構域、 l個保守分泌蛋白cog5608結構域和1個低復雜度區; ( 2 )在功能位點上, 152全長cdna編碼的蛋白質具有酪氨酸硫酸化位點、多了l個酪氨酸激酶磷酸化位點和1個可能的天冬氨酸富集區,但沒有n糖基化位點; ( 3 )擬南芥類似晚期胚胎發生高豐度蛋白的lea 2結構域具有顯著性( eThe insulin works by switching on cellular signaling proteins called kinases ( specifically src, pi3k, and akt ) and a protein ( srebp ) that binds elements in dna that regulate the production of cholesterol and its relaties
胰島素功能在於激活一類叫作激酶的細胞信號蛋白(特定的致敏反應細胞,如磷脂酰肌醇( - 3 )激酶,蛋白激酶b等)以及一種dna元素結合蛋白(膽固醇調節元件結合蛋白) ,這種蛋白質能調節膽固醇及類膽固醇的生成。The insulin works by switching on cellular signaling proteins called kinases ( specifically src, pi3k, and akt ) and a protein ( srebp ) that binds elements in dna that regulate the production of cholesterol and its relatives
胰島素功能在於激活一類叫作激酶的細胞信號蛋白(特定的致敏反應細胞,如磷脂酰肌醇( - 3 )激酶,蛋白激酶b等)以及一種dna元素結合蛋白(膽固醇調節元件結合蛋白) ,這種蛋白質能調節膽固醇及類膽固醇的生成。Gc binds to mr with higher affinity than gr. this gc - receptor interaction is also controlled at the pre - receptor level by two important factors : corticosteroid binding globulin ( cbg ) and 11 b - hydroxysteroid dehydrogenases ( 11 - hsds )
糖皮質激素與受體結合的量除與血漿中糖皮質激素水平、皮質醇結合蛋白( cbg )濃度有關外,還受到細胞內受體前糖皮質激素代謝酶? 11 -羥基類固醇脫氫酶( 11 - hsd )的調節。In other cell types the gpi - linked enzymes can be released into the surrounding media by the appropriate triggers [ 42 ? 44 ]
在其它細胞類型中, gpi連接酶通過適當的激發能被釋放到周圍介質中42 44 。Producing plant phytoalexins has been recognized as the primary and dominant routines in defending system in cotton, include terpenoid, proteases and hormones in which many enzymes, such as chitinase, has been proved useful against verti - cillium in several plants, but not their functional mechanism
在棉花抗病反應中以植物抗毒素的合成為主要途徑,包括萜類、酶類和激素類3類化學物質,其中酶類物質如幾丁質酶已經在很多植物中被證明具有抗病作用,但是其具體作用途徑仍不清楚。Conclusions ? on the basis of data aailable from published clinical trials, statin therapy is associated with a small excess risk of transaminase eleations, but not of myalgias, creatine kinase eleations, rhabdomyolysis, or withdrawal of therapy compared with placebo
結論:基於可利用的臨床試驗數據,與安慰劑比較,他汀類治療存在轉氨酶升高的風險,卻與肌痛、肌酸激酶升高、橫紋肌溶解或者終止用藥無關。Pkc, an enzyme that is activated by the receptor - mediated hydrolysis of inositol phospholipids, can lead to the increase or disturbance of the transcription of some genes when stimulated persistently
Pkc是一類ca入活化,磷脂依賴性蛋白激酶,當其處于持續激活狀態時會導致某些基因轉錄活性的增強、代謝紊亂。The vfcpkl has an obvious kinase catalytic domain for ca2 + / calmodulin dependent protein kinases and serine / threonine protein kinases, and a calcium - binding domain like calmodulin
Vfcpk1具有明顯的ca ~ ( 2 + )鈣調素依賴蛋白激酶及絲氨酸蘇氨酸蛋白激酶的激酶區以及類似於鈣調素的鈣結合區。White blood cell count and creatine kinase isoenzymes in the early diagnosis of acute myocardial infarction
白細胞分類與肌酸磷酸激酶同工酶檢測結合對急性心肌梗死的早期診斷價值In order to get some functional clues from their structures, the upstream regulation region of ndrgl gene and second structure of ndrg2 protein are performed bioinformatics analysis ; we found that there are several binding sequences of some diffirent transcription factors, their functions include regulating tissue - specific gene expression, regulating expression of genes related to growth and early development of cells, besides this, regulating expression of genes under some stimulated conditions, and so on. predict in protein fold classification shows that ndrg2 belongs to alpha / beta hydrolase fold family, and there are high similarity between ndrg2 and epoxide hydrolase from bacteria, this suggests that ndrg2 protein may has enzymatic functions associated with resisting the oxidative stress, maintaining the balance of cell redox potential, involving in the metabolism process of xenobiotics or intracellular toxic molecules
研究發現呷基因的調控區存在多種轉錄因子結合位點,功能主要涉及組織特異性表達調控,細胞生長發育相關基因的表達調控,刺激反應基因的表達調控等; ndrgz蛋白在結構上屬于a小水解酶類折疊,折疊分類預測表明ndrg2與其中的的細菌環氧化物水解酶的二級結構極為相似,提示ndrgz蛋白具有一定酶活性,可能參與細胞抗氧化應激反應,維持細, an ) armtbffiofbfochmilsyn ) mdafblechmrbfobo4第四軍醫大學碩士學位論文胞內氧還電勢平衡,參與內外源有毒物質的代謝等。The neurotrophic and morphogenic activities of gdnf are mediated by its interaction with a multicomponent receptor complex formed by the ret receptor tyrosine kinase and a glycosylphosphatidylinositol ( gpi ) - anchored " accessory " receptor, gdnf family receptor alpha - 1 ( gfral )
Gdnf的神經營養作用主要是通過兩類受體亞基介導,即膠質細胞源性神經營養因子受體alpha ( gfr s )亞基和受體酪氨酸激酶ret亞基。The members of src family are non - receptor tyrosine kinases. their make an important function in a complex network of intracellular signals, such as cell growth, proliferation, transformation, apoptosis, and cell adhesion, migration. the fact that src was discovered as an oncogene suggests that src could closely involvement in cancer
而今, src已發展成為包括九個成員在內的激酶家族,隸屬于非受體酪氨酸激酶,是細胞信號轉導途徑中一類重要的信號分子,調控細胞的生長,增殖,凋亡,細胞黏附與遷移等一系列功能。We divided all stpks into 5 subfamilies according to their own structure characterizes. stk - i only possess regions similar to the typical catalytic domain of stpks, stk - ii contain wd40 repeats, stk - iii contain all kinds of regulator domain in their c - terminal region, stk - iv have their catalytic domains located in the n - terminal region, while hstk - i also have a his kinase domain of two - component system
按照stpks結構的不同可劃分為五個亞類: stk -亞類只含有一個催化區域; stk -亞類的c端含有wd40重復序列; stk -亞類的c端含有不同的調節區域; stk -亞類的催化區域位於c端, hstk -亞類則既含有絲氨酸蘇氨酸激酶的催化區域,又含有組氨酸激酶催化區域。分享友人