磷蛋的磷脂酶 的英文怎麼說
中文拼音 [līndàndelīnzhī]
磷蛋的磷脂酶
英文
phospho-protein phosphatase-
Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸蟲病疫苗研究已有60多年的歷史,大致經歷了死疫苗、活疫苗(照射致弱尾蚴疫苗)和基因工程疫苗等研究階段,產生了一些who / tdr推薦認為很有希望的疫苗候選分子,如谷胱甘肽- s -轉移酶( gst ) 、副肌球蛋白( sm97 ) 、照射致弱疫苗抗原5 ( irv - 5 ) 、磷酸丙糖異構酶( tpi ) 、曼氏血吸蟲膜內在蛋白( sm23 )和脂肪酸結合蛋白( fabp , sm14 )等,但其對宿主的保護作用均不甚理想,未能穩定地達到40或以上的保護力水平,因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑,進一步提高其保護力。Measured the protein content by lowery method and the activity of pkc by advanced takai method
蛋白激酶c是一種鈣活化的、磷脂依賴性的絲氨酸蘇氨酸激酶。Vanadate, a potent ptpase inhibitor, locks adipocyte differentiation at an early stage in the program and leds to the accumulation of p - c - crkii, a phosphotyrosyl protein that is a substrate for ptpase ha2
研究發現一種強烈的磷酸酯酶抑制劑- -釩酸鈉能夠作用於脂肪細胞的分化早期過程從而抑制其分化,並使一種ptpha2的底物即酪氨酸磷酸化的蛋白質p - c - crkii累積。The insulin works by switching on cellular signaling proteins called kinases ( specifically src, pi3k, and akt ) and a protein ( srebp ) that binds elements in dna that regulate the production of cholesterol and its relaties
胰島素功能在於激活一類叫作激酶的細胞信號蛋白(特定的致敏反應細胞,如磷脂酰肌醇( - 3 )激酶,蛋白激酶b等)以及一種dna元素結合蛋白(膽固醇調節元件結合蛋白) ,這種蛋白質能調節膽固醇及類膽固醇的生成。The insulin works by switching on cellular signaling proteins called kinases ( specifically src, pi3k, and akt ) and a protein ( srebp ) that binds elements in dna that regulate the production of cholesterol and its relatives
胰島素功能在於激活一類叫作激酶的細胞信號蛋白(特定的致敏反應細胞,如磷脂酰肌醇( - 3 )激酶,蛋白激酶b等)以及一種dna元素結合蛋白(膽固醇調節元件結合蛋白) ,這種蛋白質能調節膽固醇及類膽固醇的生成。Effects of bovine pancreatic polypeptide on phospholipase a and trypsin activities in pancreatic tissue in rats with acute pancreatitis
牛胰多肽對急性胰腺炎大鼠胰組織中磷脂酶a和胰蛋白酶活性的影響Especially, apoptin is partially similar with ribonucleotide reductase, uridylate kinase and phosphotriesterase in the amino acid sequence. the similarity between them indicates that apoptin maybe takes part in the signal pathway of apoptosis with phosphotriesterase activity or operates on hnrna with ribonucleotide reductase or uridylate kinase activity
凋亡素與它們的長序列相似性表明,它可能具有磷脂酶活性,在細胞信號通路中起作用;或者具有核糖核苦酸還原酶和尿苦酸激酶活性而對hnrna發揮作用;或者是與其中具有某種活性的蛋白質存在競爭性抑制作用。Phopholipase c - 1 ( plc - 1 ) is widely known to play an important role in regulating cell proliferation and differentiation, development of the organisms, cell transformation and oxidative stress. till now, the mechanism how phopholipase c - 1 acts can not be thoroughly illustrated, nor has the interaction between plc - 1 pathway and other signal pathways been systematically reported. this research chose 2 - de + ms as the basic method from all kinds of proteomics strategies and compared the total protein expression map of mef genetically deficient in plc - 1 ( plc - 1 - / - ) to that of wild type mef ( plc - l + / + ) aimed to find some protein spots differentially expressed, thus we can discuss the impact of knockout of plc - 1 on signal transduction initiated by growth factors such as egf comprehensively. in this way, we can study the biological function of plc - 1 and mechanism of plc - 1 pathway indirectly, which will contribute a lot to further analysis
鑒于plc - 1發揮上述作用的機制尚未完全闡明, plc - 1通路與其他信號通路間的交聯和代償尚無系統報道,又因為以往的研究方法不夠全面,本研究以野生型小鼠胚胎成纖維細胞( plc - 1 ~ ( + / + ) )和缺失磷脂酶c - 1的小鼠胚胎成纖維細胞( plc - 1 ~ ( - / - ) )為研究模型,在眾多蛋白組學策略中選擇了雙向電泳+質譜( 2 - de + ms )作為研究手段,通過對比表皮生長因子( egf )刺激24小時後上述兩種細胞的總蛋白質表達差異,全面地探討敲除plc - 1對生長因子誘導的信號傳遞的影響,從而間接研究plc - 1生物學作用、信號傳遞機制及其代償情況,為后續的深入研究打下基礎。Pkc, an enzyme that is activated by the receptor - mediated hydrolysis of inositol phospholipids, can lead to the increase or disturbance of the transcription of some genes when stimulated persistently
Pkc是一類ca入活化,磷脂依賴性蛋白激酶,當其處于持續激活狀態時會導致某些基因轉錄活性的增強、代謝紊亂。分享友人