神經膠質變性 的英文怎麼說

中文拼音 [shénjīngjiāozhíbiànxìng]
神經膠質變性 英文
gliosis
  • 神 : Ⅰ名詞1 （神靈） god; deity; divinity 2 （精神; 精力） spirit; mind 3 （神氣; 神情） expression; l...
  • 經 : 經動詞[紡織] （把紡好的紗或線梳整成經紗或經線） warp
  • 膠 : Ⅰ名詞1 （某些具有黏性的物質） glue; gum 2 （橡膠） rubber 3 （姓氏） a surname Ⅱ動詞（用膠粘） st...
  • 質 : Ⅰ名詞1 （性質; 本質） nature; character; essence 2 （質量） quality 3 （物質） matter; substance;...
  • 性 : Ⅰ名詞1 （性格） nature; character; disposition 2 （性能; 性質） property; quality 3 （性別） sex ...
  • 神經 : nerve; nervus
  • 膠質 : galotinous; colloidalmatter膠質層 gelatinous layer; 膠質電池 [電學] gelled cell; 膠質膜 cutose
  1. Glial cell line - derived neurotrophic factor ( gdnf ) was originally isolated based on its potent and specific ability to promote the survival and morphological differentiation of dopaminergic neurons and motoneurons in embryonic midbrain cultures. in addition, gdnf also support the survival and regulate the differentiation of many peripheral neurons, including sympathetic, parasympathetic, sensory and enteric neurons. gdnf also plays a crucial role outside the nervous system, as a morphogenetic factor in kidney development and as a regulator of spermatogonia differentiation

    Gfr 1與gdnf結合位點的研究膠質細胞源性神經營養因子（ gdnf ）對多巴胺能神經元、運動神經元、感覺神經元、腸道神經元等多種神經元具有促進存活及保護作用，它還能促進腎臟的發育和精原細胞的成熟，因此，極有希望用於治療神經損傷和神經系統退行性病變。
  2. Methods : hyperosmotic pressure animal model was established by administering 3 % sodium chloride as drinking water to rats or increasing osmotic pressure of the culture medium. osmoregulation positions in the brain, reciprocal projection pathways between the medullary visceral zone ( mvz ) and supraoptic nucleus ( son ) or hypothalamic paraventricular nucleus ( pvn ), oscillation of intracellular calcium in cultured neurons and astrocytes were studied by means of anti - fos, glial fibrillary acidic protein ( gfap ), tyrosine hydroxylase ( th ) or vasopressin ( vp ) multiple imrnunohistochemical staining, immuno - electronic microscope, wga - hrp retrogradely tracing and cell culture methods. results : ( 1 ) fos positive neurons within the mvz, parabrachial nuclei, locus ceruleus, pvn, son, subfomical organ increased markedly

    方法：通過給予大鼠飲用3氯化鈉或提高培養基滲透壓濃度的方法復制高滲刺激模型，主要採用抗fos 、膠質原纖維酸性蛋白（ gfap ）和酪氨酸羥化酶（ th ） （或加壓素? vp ）免疫組織化學多重染色、免疫電鏡、 wga - hrp束路追蹤結合免疫組織化學多重染色、細胞培養等實驗方法，系統觀察了中樞參與滲透壓反射的調控部位、下丘腦視上核（ son ）神經元? ast超微結構的變化、延髓內臟帶（ mvz ）和son及下丘腦室旁核（ pvn ）之間往返投射通路和神經元的性質及其與ast的關系、培養神經元和ast內鈣波的變化。
  3. Tissue sections from every animal were double - labeled with the antibodies of map - 2, cox - 2, gdnf, caspase - 3 and either the neuron - specific antibody neuronal nuclear protein ( neun ) or the astroglial - specific marker glial fibrillary acidic protein ( gfap ). we carried out a series of research to explore the effects and mechanism of map - 2, cox - 2, gdnf, caspase - 3 during tbi and trie d to provide some useful theory basis for both the treatment of tbi in the practice and forensic medicine

    並通過上述指標分別與神經元特異性標志物神經元核蛋白（ neuronalnuclearprotein ， neun ）和星形膠質細胞特異標志物膠質纖維酸性蛋白（ glialfibrillaryacidicprotein ， gfap ）進行免疫組織化學雙染色，探討腦損傷后神經元及神經膠質細胞反應性變化情況及其分子生物學機制，以期為腦損傷研究提供有益的數據材料，也為以上指標在法醫學實際檢案的應用提供必需理論依據。
  4. During induced differentiation we observed the changes of the cell morphology, the number of the cells and the expressions of neuron specific enolase ( nse ) and glial fibrillary acidic protein ( gfap ) in the cells

    同時觀察誘導期間細胞形態數目的變化及神經元特異性烯醇化酶heuronsrecificenolase ， nse ）和膠質纖維酸蛋白（ liali brillnyacidicprotein ， gfap ）的表達情況。
  5. In the present experiment studies, an acute traumatic model of lateral cortical impact was employed to study expressive changes of microtubule associated protein - 2 ( map - 2 ), cyclooxygenase - 2 ( cox - 2 ), glial cell line - derived neurotrophic factor ( gdnf ), caspase - 3 mrna and protein after brain injury in rats. immunocytochemical staining, western blotting, nucleic acid in situ hybridization with an oligonucleotide probe and computer image analysis were used to detect the dynamic changes of map - 2 mrna, cox - 2 mrna, gdnf mrna, and caspase - 3 mrna in the cortex after moderate traumatic brain injury ( tbi )

    本實驗從自行設計大鼠腦損傷落體打擊器開始，先行建立了一個便於觀察和施加處理因素、控制性好、重復性好的動物模型，選用30g擊錘從25cm高處下落，沖擊應力d為355 . 09kpa ，打擊大鼠右頂部，造成中等程度的閉合性腦損傷，從病理形態學、組織超微結構觀察及微管相關蛋白- 2 （ microtubuleassociatedprotein2 ， map - 2 ） 、環氧合酶- 2 （ cyclooxygenase2 ， cox - 2 ） 、膠質源性神經營養因子（ glialcellline - derivedneutrophicfactor ， gdnf ） 、 caspase - 3基因及蛋白表達的時間性變化，詳盡系統地闡述腦損傷后各指標變化的時間規律性及表達差異可能的形成機制。
  6. Nuclear factor - kb ( nf - kb ) is one kind of cell transcription factor that exist in many kinds of cells in nervous system. it is also has great association with the process of neuronal degeneration and apoptosis. from the above we can see that tbi, secondary brain injury, apoptosis and cytokines associated tightly

    細胞核因子b （ nuclearfactor - b ， nf - b ）是一類普遍存在的細胞轉錄因子，功能性nf - b復合物存在於神經系統的各種類型的細胞中，包括神經元、星形膠質細胞、小膠質細胞、少突膠質細胞中，在神經細胞變性和凋亡過程中起十分重要的作用。
  7. It is known that astrocytes take a key role in the response to hypoosmotic stimulation : astrocytes can perceive the change of osmotic pressure and release taurine which then activates glycine receptors on the neurons, and inhibits the release of vp from the neurons in son

    現已發現星形膠質細胞在對低滲刺激的反應中起關鍵性的作用：星形膠質細胞感受滲透壓的變化，通過大量釋放牛磺酸（ taurine ） ，作用於神經元上的甘氨酸（ glycine ）受體，從而抑制神經元釋放血管加壓素（ vasopressin ， vp ） 。
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