移植耐受 的英文怎麼說
中文拼音 [yízhínàishòu]
移植耐受
英文
transplantation tolerance-
Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s. despite success of current immunosuppressive drugs, transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft. there are several different mechanisms such as clonal deletion, anergy, neglect, immuno regulation. which maintain tolerance to self - antigen. some strategies, derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection
二十世紀五十年代以來,器官移植的進展使同種異體器官移植成為治療多種器官終末期疾病的有效手段。盡管目前免疫抑制方案非常有效,但免疫耐受仍是移植免疫學家和外科醫生關注的課題。有多個機制使免疫系統對自身抗原保持耐受,如:克隆清除、忽略、失能、免疫調節。Tgf - and simultaneous immune suspression of keratoplasty
與角膜移植誘導的免疫耐受2. rat orthotopic liver trarlsplantation was performed in the strong rejecter combination of bn ( rtl " ) to lew ( rtl l ). this al1ogenic rejection model was stable and the survival time without immunosuppression agents was less than three weeks ( the average survival time was l 6. 6 i 2. 5 days, n = 5 )
建立了大鼠bn ( rt1 ~ n ) lew ( rt1 ~ l )原位肝移植同種異體排斥模型,該模博士學位論義基因轉移hu la個ig誘導大鼠移植肝免疫耐受的實驗研究中文摘要型排斥反應時間較為恆定,在不應用免疫抑制劑的情況下,生存期3周(平均生存時問人66士2The results suggested that human hscs can engraft into rat and differentiate into multilineage under certain microenvironment. thus, the human / rat xenograft model may provide a useful and convenient method for assay human hscs in vivo
新生大鼠免疫系統發育不完善,對異種抗原可形成免疫耐受,是很好的研究異種移植的實驗動物,且經濟。Mechanisms of surrogate tolerogenesis for xenotransplantation induced by chimeric donor with mononuclear cells derived from cord blood
造血細胞嵌合體供者誘導異種移植物的免疫耐受Hematopoietic chimerism produces durable and robust immune tolerance to kidney allografts, although incomplete tolerance to donor skin grafting
造血嵌合能夠對腎移植產生持久有力的免疫耐受,但對于皮膚移植無效。Recent findings : grafts are not merely passie ictims, but rather participants. therapeutic tolerance is an operational term in which the graft is spared damage despite lack of ongoing drug immunosuppression
新近發現:移植物不僅僅只是被動的受害者,而且還是參與者。治療性耐受是一個操作術語,在不需藥物產生免疫抑制作用情況下,移植物免於(宿主產生的)損害。It is particular important to conduct preoperative preparation, perioperative anesthesia and monitoring, the prevention and treatment of the postoperative complications, and the monitoring of the toxic and side effects of immunosuppressive agent, etc. the postoperative complications, especially lung infection, are the main dead factors for advanced age crf patients receiving kidney transplantation
結論高齡並非腎移植的絕對禁忌證;高齡患者耐受力差,常伴隨其它疾病,術前準備、術中麻醉及監測、術后並發癥的防治、免疫抑制劑毒副作用的監測尤為重要;術后並發癥,尤其是肺部感染是高齡患者的主要死亡原因。Recent developments in basic and translational immunology open new exciting perspectives for clinical cell and organ transplantation, including the development of novel immunosuppressive agents, new diagnostic tools and validation of biomarkers for the prediction of rejection as well as the induction of tolerance
最近基礎和移植免疫學的發展為臨床細胞和器官移植提供了全新的遠景,包括全新免疫抑制藥物的發展、全新的排斥反應的診斷手段、有效的排斥反應預測生物因子、免疫耐受誘導等等。Such ceasefires faour induction of tolerance through the recruitment and induction of regulatory t cells
這些調停措施通過募集和誘導調節性t淋巴細胞產生移植耐受。These shifts hae spawned noel strategies for long - term graft acceptance through reprogramming of the immune system. new paradigms proide the focus of this reiew
這些範式轉換誕生了新的治療策略,通過重組機體免疫系統實現長期的移植耐受(存活) 。本綜述探討的主要焦點是新的範式。Advancement of corneal transplantation immune tolerance
角膜移植免疫耐受的研究進展Inducing transplantation tolerance to rat cardiac allografts by intrathymic inoculation at the day of transplantation
胸腺應急修飾誘導大鼠同種心臟移植免疫耐受Purpose : this study was designed to determine the potential of the pretreatment with fty720 ( fty ) to prolong cardiac allograft survival and explore its operational mechanism
目的:為進一步探討fty720的作用機制,探索利用該藥誘導移植免疫耐受的可能途徑,我們進行了本研究。Donor specific organ transplantation immune tolerance, which is defined as no medication ( routine immunosuppressive agents ), no rejection and no infection after mhc mismatched organ transplantatlon, is the trend of organ transplantation
供體特異性器官移植免疫耐受,即在接受組織配型不相容的器官移植或加短療程治療后達到不用藥(常規免疫抑制劑) 、不排斥、不感染的「三不狀態」是器官移植發展的方向。In terms of regulatory t cell, cd4 + cd25 + t cell is representitive. ln naive individuals, cd4 + cd25 + t cells function as self tolerance, in recipients with long term survival allograft. they play an important role in suppression of allograft rejection. immune regulation potent cd4 + cd25 + t cells can be recovered from recipients with long term survival allografts. such regulatory t cells can suppress t cell mediated rejection in vitro and in vivo
其中, cd4 + cd25 + t細胞是具有代表性的調節性t細胞。在未經處理的機體內, cd4 + cd25 + t細胞對保持自身耐受起著關鍵的作用。在同種異體移植物長期存活的受體內, cd4 + cd25 + t細胞對抑制同種異體移植物排斥反應也起到很重要的作用。With administration of ctla4 - ig, short - term blockade of cd28 - mediated corecognition resulted in prolonged graft survival and tolerance in mhc mismatched rodent models
給予huctla4 - ig ,短期阻斷cd28介導的共識別可導致mhc不匹配的嚙齒類模型中移植物的長期存活與耐受。The itn is currently in the planning stages of follow - up studies designed to test emerging tolerance therapies in islet transplantation
Itn目前正在計劃隨訪試驗,用來檢驗日益增多的胰島移植的耐受療法。Islet cell transplantation now forms the basis of a prospective multicenter trial under the aegis of the immune tolerance network
在免疫耐受網路系統的支持下,現在已經開展胰島移植前瞻性多中心試驗研究。Thirty days after bmt, immunologic tolerance were evaluated by using skin grafting
在骨髓移植后30天,用尾部皮片移植法測定免疫耐受情況。分享友人