突變劑 的英文怎麼說
中文拼音 [tūbiànjì]
突變劑
英文
mutagens-
Mutation are produced by a number of chemicals.
許多化學試劑能產生突變。Further analysis reveals that expression of ( - arrestin2 strengthened cxcr4 - mediated activation of both p38 mapk and erk and the suppression of ( - arrestin2 expression blocked the activation of two kinases
進一步的研究發現， - arrestin2可以增強cxcr4介導的erk及p38mapk的激活，但只有p38mapk的特異性抑制劑及顯性失活突變體才可以阻斷- arrestin2對趨化的增強作用。Study on removing dietary mutagen by antimutagenic lactic acid bacteria
抗突變活性乳酸菌對膳食中誘變劑去除作用研究進展Environmental mutagens can also induce mutations at undamaged sites and result in the so - called nontargeted mutation
環境誘變劑引起的突變也可發生在非dna損傷部位，我們稱之為非定標性突變（ nontargetedmutagenesis ） 。However, environmental mutagens can also induce mutations at undamaged sites and result in the so - called nontargeted mutagenesis
但是環境誘變劑引起的突變也可發生在非dna損傷部位，它被稱之為非定標性突變（ nontargetedmutagenesis ） 。They can convert plasminogen into plasmin and thus degrade fibrin. despite the widespread use of established thrombolytic agents such as streptokinase, t - pa and u - pa, all these agents suffer from a number of inadequacies including resistance to reperfusion, occurrence of coronary reocclusion and bleeding complications
一些pa突變體及新型溶栓劑，如k2p tnk - pa和star等的臨床實驗結果表明它們在延長體內半壽期增強對血纖維蛋白選擇性和溶栓效率等方面有較大的改進。The inhibitory effect of pule liquid on the mutagenicity of several hair coloring creams
普樂液體外抑制多種染發劑致突變作用研究The quest continues for plasminogen activators with higher potency, specific thrombolytic activity, fibrin selectivity and longer half - life time. the recent progress in the protein engineering of plasminogen activators, including t - pa, u - pa, streptokinase, staphylokinase and other novel plasminogen activators, was presented in this article
一些pa突變體及新型溶栓劑，如k2p tnk - pa和star等的臨床實驗結果表明它們在延長體內半壽期增強對血纖維蛋白選擇性和溶栓效率等方面有較大的改進。In this study, lexa mutant of deinococcus radiodurans xe has been successfully constructed. the survival curve of this strain was measured using colony formation assay after treatment with different doses of radiation and different times of mmc
本研究利用已構建的抗輻射菌lexa基因突變體菌株xe ，經受不同劑量射線照射和不同時間的mmc作用，平板菌落計數，繪制存活曲線。Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts. among the adducts, o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties, which can eventually lead to chromosomal aberrations, point mutations, and cell death. this lesion also appears to be involved in tumor initiation, particularly in gastric carcinogenesis
單功能烷化劑n -甲基- n -硝基- n -亞硝基胍（ mnng ）是一種在環境中廣泛存在的化學誘變劑和致癌劑，它能和dna及蛋白質等生物大分子形成加合物（ adduct ） ，其引起的與突變有關的主要dna損傷類型是o ~ 6 -甲基鳥嘌呤，這種損傷與腫瘤尤其是胃癌的發生密切相關。Plants can obtain high doses glyphosate tolerance if the enzyme of this gene is over produced and accumulated or herbicide - insensitive enzymes produced due to some amino acid mutation in active sites
植物中epsp合成酶的過量表達或某些活性位點氨基酸的突變對高劑量的草甘膦有較強的耐受性。Study on the mutagenic effects of an oxidative hair dye
一種氧化型染發劑的致突變性研究Studies of genes related to heart development in drosophila contribute to reveal the mechanisms of human heart development and the congenital heart diseases. to clone and identify new genes that control the heart development, by a way of chemical mutagen, ems, we have established 1, 200 balanced - lethal lines on chromosome 2 and 3. with the screening the 330 stocks with immunochemical method using heart - specific antibody, mab. no. 3, we detected 60 lethal lines showing heart mutant phynotype
為了克隆和鑒定控制心臟發育的新基因，本研究利用化學誘變劑甲磺酸乙酯大規模地誘變果蠅，並且建立了1200個第二和第三染色體的平衡致死系，利用心臟組織特異抗體mab . no . 3對其中330個品系進行免疫化學方法篩選，觀察到有60個致死系表現出心臟突變表型， 20個品系的心臟突變表型有待進一步證實。Main point of sdt is : when an interwell tracer test is conducting, the short - term changes of injection and / or production rates of the wells involved can generate abnormal tracer responses at the wells where tracer is already in producing ; by analyzing the abnormal responses, information on flows produced at the production well from different directions can be obtained
造成採油井上示蹤劑響應的突變，據此評價採油井中不同方向k來水之問的關系。在傳統的井間示蹤測試中使用微擾法，可以更快地獲得測試結果並且還可以獲得其它方向水流的信息。Study on toxicity and mutagenic effects of quaternary ammonium compound detergent
季氨化合物洗消劑的毒性及致突變作用研究Mms, a kind of dna - damaging agent, predominantly methylates ring nitrogens of pyrine, leading to dna double - strand breaks, point mutation and so on
甲磺酸甲酯（ methylmetbanesulfonate ， mms ）是一種能夠損傷dna的烷化劑，主要使dna嘌呤堿基上的o 、 n甲基化，造成dna雙鏈斷裂、點突變。Therefore, it is important to study the profiles of gene expression, which will help understand the global cellular stress responses to chemical carcinogens, and further elucidate the mechanisms of nontargeted mutagenesis
所以，從整體上研究烷化劑作用后細胞基因表達譜改變，對于了解化學致癌物誘發的哺乳動物細胞應激反應的全貌和揭示非定標性突變的發生機制具有非常重要的意義。In our laboratory, a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0. 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0. 2m mnng for 2. 5h, then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture. we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells. this kind of mutation did not occur immediately after mnng exposure
我們實驗室曾用一特殊的突變檢測系統，直接證明dna損傷劑可在哺乳動物細胞誘發非定標性突變：首先用低濃度（ 0 . 2 m ）的短壽烷化劑mnng （半壽期為1 . 1hr ）處理細胞2 . 5h后，繼續培養24h ，將重組有用作突變檢測的靶基因supftrna基因的穿梭質粒pz189轉入細胞復制，發現在未受致癌物直接攻擊的穿梭質粒中有較自發突變率高5倍以上的靶基因突變。From 19 arabidopsis male sterile lines isolated from an ethyl methanesulphonate - induced ( ems - induced ) population, a total of four male sterile mutants were screened with each mutant controlled by a single recessive gene
首先對19個經化學誘變劑ems處理得到的雄性不育突變體進行背景純化和遺傳分析，從中篩選到四個單個隱性基因控制的雄性不育突變體（ ec2 - 157 、 ec1 - 188 、 ec2 - 115和ec2 - 214 ） 。Abstract : plant responses to salt stress via a complex mechanism, including sensing and transducing the stress signal, activating the transcription factors and the corresponding metabolizing genes. since the whole mechanism is still unclear, this review emphasize the biochemical events during the plant adaptation to salt stress referring to an index of importance : the homeostasis in cytoplasm, the biosynthesis of osmolytes and the transport of water. most of these biochemical events were elucidated by study of halophyte and salt - sensitive mutations, also many important genes involved were cloned and used to generate stress - tolerance phenotypes in transgenic plants. on the other hand, about the molecular mechanism in signal transduction, the research of arabidopsis mutations and yeast functional complementation provided helpful traces but not full pathway
摘要植物對鹽脅迫的耐受反應是個復雜的過程，在分子水平上它包括對外界鹽信號的感應和傳遞，特異轉錄因子的激活和下游控制生理生化應答的效應基因的表達.在生化應答中，本文著重討論負責維持和重建離子平衡的膜轉運蛋白、滲調劑的生物合成和功能及水分控制.這些生理生化應答最終使得液泡中離子濃度升高和滲調劑在胞質中積累.近年來，通過對各種鹽生植物或鹽敏感突變株的研究，闡明了許多鹽應答的離子轉運途徑、水通道和物種特異的滲調劑代謝途徑，克隆了其相關基因並能在轉基因淡水植物中產生耐鹽表型;另一方面，在擬南芥突變體及利用酵母鹽敏感突變株功能互補篩選得到一些編碼信號傳遞蛋白的基因，這些都有助於闡明植物鹽脅迫應答的分子機制。分享友人