糖抗原 的英文怎麼說
中文拼音 [tángkàngyuán]
糖抗原
英文
carbohydrate antigen-
Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸蟲病疫苗研究已有60多年的歷史,大致經歷了死疫苗、活疫苗(照射致弱尾蚴疫苗)和基因工程疫苗等研究階段,產生了一些who / tdr推薦認為很有希望的疫苗候選分子,如谷胱甘肽- s -轉移酶( gst ) 、副肌球蛋白( sm97 ) 、照射致弱疫苗抗原5 ( irv - 5 ) 、磷酸丙糖異構酶( tpi ) 、曼氏血吸蟲膜內在蛋白( sm23 )和脂肪酸結合蛋白( fabp , sm14 )等,但其對宿主的保護作用均不甚理想,未能穩定地達到40或以上的保護力水平,因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑,進一步提高其保護力。The complex formed by cnbr - activated alginate and antibody is aggregated to the surface of the paraffin - graphite - chitosan electrode by electrostatic adsorption ( coacervation ). the concentration of sjag can be detected by determining the redox current of o - aminophenol, which oxidized by h2o2 in the presence of hrp. moreover, the immunosensor shows some improved performances including high sensitivity, selectivity and less non - specific adsorption
褐藻酸鈉?抗體復合物通過靜電吸附作用被凝集到含石墨?石蠟?殼聚糖組分的電極表面,然後與抗原和酶標抗原進行競爭反應,以鄰氨基酚為電子媒介,通過測定酶催化下雙氧水對其氧化的電流大小來間接測定抗原的濃度。Glycoproteins act as important antigenic determinants to which host immunity is often directed.
糖蛋白是重要的抗原,決定族宿主的免疫性常常針對著它們。Certain antigens, enzymes, and hormones are glycoproteins
一些抗原、酶、激素都屬于糖蛋白。And amino acids of strain mrv between antigenic site and glycosylation site is different. to some extent, it will decide and change the antigen of mrv
Mrv的抗原部位和糖基化位點氨基酸均有變異,這種變異可能在不同程度上會改變毒株的抗原性。This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗,將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合,獲得新抗原- 35肽序列;並在合成、純化後分別與弗氏佐劑、免疫刺激復合物( iscoms )混合后免疫不同遺傳背景的雌性小鼠,觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變:以及在ivf下,新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。Efficacy of oral immunization with serotype 3 pneumococcal polysaccharide
3型肺炎球菌多糖抗原口服給藥途徑的效力研究Accurate diagnosis and effectiv veccination are main means for the prevention of porcine diarrha researh showed tha the outer capsid glycoprotein vp7 of prv particle is major protective anigen
病毒外膜的vp7糖蛋白是rv的主要免疫保護性抗原,由其刺激機體產生的抗體對中和病毒、消除感染起主要作用。There are some nutritional factors and antinutritional factors in soy, nutritional factors include soy phospholipid and soy isoflavone, antinutritional factors include trypsin inhibitors, antigenic protein, lectins and phytic acid, soy oligosaccharides and soy saponins have nutritional and antinutritional effects
摘要大豆中含有抗營養因子和營養因子,營養因子包括大豆磷脂、大豆異黃酮等,抗營養因子包括蛋白酶抑制因子、抗原蛋白、凝集素、植酸等,大豆低聚糖和皂甙具有營養和抗營養雙重作用。Glutamic acid decarboxylase ( gad ) is a major target antigen of humoral and cellular autoimmunity in type 1 diabetes mellitus. the autoantibodies against gades protein is the most early and specific marker for type 1 diabetes mellitus, so it has been applied to the clinical practices widely
谷氨酸脫羧酶( gad )是胰島b細胞的一種主要自身抗原,與1型糖尿病細胞免疫和體液免疫有密切關系,已廣泛應用於臨床,作為糖尿病預測、診斷、分型、療效監測的重要依據。The acellular matrix treated by sds or glutaraldehyde should be cleaned by normal saline, or there will be cytotoxicity in it. the results of cell culture and implantation experiment demonstrate the high degree of cytocompatibibity and biocompatibility of this kind of acelluler matrix
A半乳糖殘基是豬到人的主要異種抗原,會導致超急性免疫排斥,要實現豬到人的異種移植首先要去除的就是o gal 。Analysis of expression of
寡糖抗原的表達Construction and identification of recombinant canine adenovirus type 2 expressing exogenous rabies glycoprotein
表達狂犬病毒糖蛋白抗原的重組犬2型腺病毒的構建及鑒定According to the deduced amino acid of g gene, there are two glycosylation sites in strain 119 and gxbm at position 37 and 319. there is few change in important neutralizing antigenic epitope and in some antigenic sites related with pathogenicity
119和gxbm株g基因推定氨基酸均有37 、 319兩個糖基化位點,重要的抗原位點及致病性相關位點基本沒有變化。Second, a prokaryotic expression construct, obtained from invitrogen transformed into prokaryotic and induced to express vp1 protein. the expressed vp1 fusion protein was purified by affinity chromatography using glutathione - agarose resin and used in elisa and western bolt analysis as the antigen. the elisa and western blot results showed that the anti - fmdv antibody was elicited specifically against vp1 antigen
第二,為了得到抗原蛋白,將vp1的原核表達質粒pgex - 4t - vp1轉化入大腸桿菌bl21中,經iptg誘導,裂解細胞後用瓊脂糖珠進行純化,用elisa和westernblot進行檢測,結果表明誘導表達出所需大小的融合蛋白。Classical swine fever ( csf ) is one of major contagious diseases in pig breeding industry. in order to gain massive diagnostic antigen csfv, and large scale of csfv specific major protective antigen protein ( e2 envelope glycoprotein ) in eucaryotic cells, which are prepared into subunit vaccine for effective prevention against csf
豬瘟是危害養豬業的主要傳染病,為了得到大量的豬瘟病毒特異性診斷抗原,並試圖在真核細胞中大量表達豬瘟病毒特有的免疫保護性抗原,即e2囊膜糖蛋白,為進一步制備豬瘟亞單位疫苗有效預防本病奠定基礎。This implied that the 31 kd initiated from atg codon of pres2 gene, the 30 kd encoded by the s gene was glycosylated form of s protein, the 25 kd initiated from atg codon of the pres2 gene was disassembled form of 31 kd and the 28 kd was a glycosylated form of25kd. under optimal condition the expression level of foreign gene was considerably affected on hosts ( silkworm race ), the highest difference of expression level in various races can reach up to 8 times
推測31kd處的條帶為起始於presz起始密碼子atg的表達產物,同時具有pres : z和s抗原性, 30kd處的雜交條帶為起始於s基因起始密碼子atg表達產物的糖基化形式, 25kd的條帶可能是中蛋白的降解產物,而28kd的條帶可能25kd條帶的糖基化形式。In immuno - blotting, these fragments reacted specifically with hepatitis c patients " sera, suggesting that e. coli - derived e2 proteins carried hcv e2 - specific, glycosylation - and - conformation - independent epitopes
在免疫印跡檢測中,上述片段與丙型肝炎病人血清有特異性反應,表明大腸桿菌系統表達的e2蛋白攜帶有hcve2特異的、不依賴于糖化和立體構象的抗原決定簇。By immunizing rabbits with aa 192 - 326 fragment, polyclonal sera were obtained that were able to recognize e1 proteins expressed in both e. coli and mammalian cells, suggesting that e. coli - derived e2 proteins carried hcv e1 - specific, glycosylation - and - conformation - independent epitopes
利用aa192 - 326免疫家兔,獲得了可識別大腸桿菌和哺乳動物細胞表達之e1蛋白的多抗血清,表明大腸桿菌系統表達的e1蛋白攜帶有hcve1特異的、不依賴于糖化和立體構象的抗原決定簇。The polymorphisms of transporter associated with antigen processing genes among type 1 diabetes mellitus
抗原肽處理相關運載蛋白體基因多態性與1型糖尿病分享友人