細胞分化抗原 的英文怎麼說

中文拼音 [xìbāofēnhuàkàngyuán]
細胞分化抗原 英文
t-cell differentiation antigens
  • 細 : 形容詞1 （條狀物橫剖面小） thin; slender 2 （顆粒小） in small particles; fine 3 （音量小） thin ...
  • 胞 : Ⅰ名詞1 （胞衣） afterbirth2 （同一個國家或民族的人） fellow countryman; compatriot Ⅱ形容詞（同胞...
  • 分 : 分Ⅰ名詞1. （成分） component 2. （職責和權利的限度） what is within one's duty or rights Ⅱ同 「份」Ⅲ動詞[書面語] （料想） judge
  • 抗 : Ⅰ動詞1 （抵抗; 抵擋） resist; combat; fight 2 （拒絕; 抗拒） refuse; defy 3 （對等） contend with...
  • 原 : Ⅰ形容詞1 （最初的; 原來的） primary; original; former 2 （沒有加工的） unprocessed; raw Ⅱ動詞（原...
  • 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
  1. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  2. After the recombinant plasmid pcdna3. 1 / ts87 was identified by digestion of hindlll and bamh i, it transformed into cos7 by lipofectamine. expression product was identified by immunohistochemical method, sds - page and western - blot. the immunocytochemistry result has shown that specific brown - staining grains were found in the cytoplasm of cells transformed by recombinant plasmid versus not seen in cells transformed by pcdna3. 1 or normal cells ; the sds - page result has revealed that a band about 3 8kb was found in cell lysis transformed by recombinant plasmid versus not in cells transformed by pcdnas. l or normal cells ; the western - blot result has showed that only the band about 38kd was recognized by sera from rabbit infected by t. s artificially and sera from rabbit immunized with soluble antigen of t. s and with protein expressed by ts87 gene and by a monoclonal antibody of t. s

    通過細胞的免疫組化，細胞裂解物的sds - page電泳， westem - blot分析檢測目的基因的表達情況。免疫組化結果顯示：重組質粒轉染的細胞質中有棕褐色顆粒，而空載體轉染細胞及正常細胞無此現象；細胞裂解物sds - page電泳結果顯示：只有重組質粒轉染的細胞在約38kd處有明顯的蛋白帶，這與理論計算的ts87基因表達蛋白的分子量為38kd基本一致； western - blot分析結果顯示：約38kd的蛋白帶能夠分別被旋毛蟲感染兔血清，成蟲蟲體可溶性抗原免疫兔血清， ts87基因原核表達蛋白免疫兔血清（ ts87血清）以及一株具保護性的旋毛蟲單抗特異識別。
  3. The endocrine cells in the digestive and glands of alligator sinensis embryos aged from 8th to 55th day were localized and compared by using immunohistochemical method with thirteen kinds of antiseras of hormone. during the development of pancreas in alligator sinensis embryos, somatostatin ( ss ) immunoreactive ( ir ) cells, 5 - hydroxytryptamine ( 5 - ht ) - ir cells, glucagon ( glu ) - ir cells, epidermal growth factor ( egf ) - ir cells appeared on 18th day. no p53 protein - ir cell, gastrin - ir cell, testosterone - ir cell, chromogranin a - ir cell, vasoactive intestinal polypeptide - ir cell, epithelial membrane antigen - ir cell or insulin - ir cell was found in the pancreas of alligator sinensis embryos

    本實驗採用免疫組織化學技術，應用13種不同的抗血清，對孵育時間8 ? 55天揚子鱷胚胎消化道及消化腺內分泌細胞的種類進行鑒別、定位和比較，結果如下：揚子鱷胚胎胰腺中，生長抑素、 5 ?羥色胺、胰高血糖素、表皮生長因子、胰多肽免疫反應陽性細胞出現于第8天； p物質免疫陽性細胞出現于第18天； p53 、胃泌素、睪酮、嗜鉻素a 、血管活性腸肽、上皮膜骯原、胰島素免疫陽性細胞在各期揚子鱷胚胎胰腺中均未發現。
  4. Anti - if - protein antibodies were used as probes for immuno - fluorescence, and the reactions of them with different parts of the cell were detected, which suggested the possibility of the existence of the intermediate - like filaments in the cytoplasm. those proteins homologous to the antibodies distributed regularly in the protoplasm. to characterize the corresponding proteins, sds - page and immunoblots were utilized. the 21, 23, 33 and 68kd proteins were distinguished among the diverse protein constituents of the cell. some of these proteins also showed the cross - reactivities with anti - if - proteins antibodies derived from higher organisms. these two evidences both contributed to the homology of some proteins in

    以抗中間纖維蛋白抗體作為探針進行免疫熒光實驗，得到細胞內不同部位的陽性反應，暗示原生質中可能存在類中間纖維。這些同源蛋白的胞內分佈具有一定的規律性。進一步採用sds - page和免疫印跡技術研究它們的生化性質，發現4種主要蛋白明顯有別于胞內其他蛋白組分。
  5. Homology analysis showed that pta1 molecule is highly conserved among human, gibbon and monkey, sharing the same sequence about 93 % ~ 95 % at the protein level. pta1 and monoclone antibodies fmu1 - 7 were named as cd226 in 7th workshop and conference on human leucocyte differentiation antigens ( hlda )

    Pta1以及我室制備的一套mabfmu1 - 7在2000年第7屆人類白細胞分化抗原國第四軍醫大學碩士學位論文中文摘要際協作會議中被命名為cd226 。
  6. The results showed the technique suit either completely to immunohistochemical study of the pulp matrix and of the cell surface expression that was weaker antigenicity, or to enzyme histochemical staining of the dental pulp

    結果表明，它完全滿足牙髓基質和抗原性較弱的細胞表面標志等成分的免疫組化染色，同時也適用於牙髓的酶組織化學染色。
  7. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  8. Elicitors molecules that initiate cell signaling pathways leading to the activation of plant defense genes and the production of phytoalexins and other defensive chemicals in response to infection by a pathogen

    誘導子：可以引發細胞信號通路的分子，使植物防禦基因、植物抗毒素及其他防禦性化學物質製品被活化以防病原體的感染。
  9. Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc

    而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。
  10. Objective : to construct prokaryotic and eukaryocytic expression plasmids of the shortened hepatitis b surface antigen, and express the target proteins by iptg induced in escherichia coli

    目的：構建截短的乙型肝炎表面抗原分子的原核和真核表達重組質粒，然後分別在大腸桿菌中誘導表達並純化表達蛋白及在真核細胞中表達目的基因，並檢測其抗原特性。
  11. Chromosome numbers were no remarkable difference with the control. analysis of isoenzyme ( peroxidase, cytochrome oxidase, esterase ) and rapd indicated that the regenerated plants from protocalli were different with the control. protoplasts were isolated from agrobacterium rhizogenes a ^ transformed cell line of medicago sativa l.

    染色體檢查，同工酶（過氧化物酶、細胞色素氧化酶、酯酶）和rapd分析表明，來源於抗性系原生質體的再生植株具一定的遺傳穩定性，但與野生型相比亦發生了一些變異。
  12. Florenes va, amdal s, myklebost o, et al. levels of nm23messenger rna in metastatic malignant melamomas : riverse correlation to disease progression. cancer res, 1992 : 52 ( 21 ) : 6088

    林星石，袁玫，孫小華，等.增殖細胞核抗原與大腸癌的分化、分期及預后的關系.中華病理學雜志， 1995 ; 24 （ 6 ） : 383
  13. Methods : the balb / c mouse is immunized with gene recombinant antigen p24 for four times in 2 months. the spleen cells of immunized mouse is hybridized with sp2 / 0 by peg, and the positive cell clones secreting the antibody to antigen p24 are detected by indirect elisa. through three clonings less diversed anti - p24 hybridoma cells are gained

    方法：基因工程p24抗原免疫小鼠4次，歷時2個月，取脾細胞與骨髓瘤細胞株sp2 0 ，用peg融合， hat選擇培養和間接elisa篩選分泌抗p24抗體陽性的雜交瘤細胞，三次克隆化后得穩定分泌抗p24抗體的雜交瘤細胞株。
  14. Methods the 54th generation of transformed human embryonic tendon cells and artificial composite materials of carbon fibers ( cf ) and polyglycolic ( pga ) were co - cultured in vitro to construct tet. lt was frozen in liquid nitrogen with four kinds of cpa for 2 months. post - thawed quickly and transplanted into hind limbs of nude mice, and repaired the defects of achilles tendon. after 2, 4, 6, 8, 12 weeks, the morphological, histological, ultrastructure, short tandem repeat loci and immunohistochemistry examination were detected, and biomechanical strength of tet were examined. result tendon cell survived and could secret type i collagen after 12 weeks to transplanted into nude mice. in the group of dmso + raffmose + kh2o4, vacuole in mitochondrion degraded i tendon cell ranged in order, abundant collagen fibers were found and linked each other and the biomechanical strength was increased as time elapsed. c onclusion dmso + raffmose + kh2o4 could protect tet in deep low temperature

    組織工程肌腱制備完成後在四種抗凍劑保護下液氮凍存2月；快速復溫后植入裸鼠以修復跟腱缺損， 2 、 4 、 6 、 8 、 12周后取出，觀察形態學、組織學、電鏡和免疫組織化學變化，短串聯重復位點檢測和生物力學變化。結果實驗組組織工程肌腱體內植入12周后仍有肌腱細胞存活並分泌型膠原；隨著時間延長， 10二甲基亞碸（ dmso ） +棉子糖（ 30mmol l ） + kh _ 2po _ 4 （ 25mmol l ）組線粒體空泡減少，肌腱細胞排列整齊，膠原纖維增粗並連接，抗拉強度增高。
  15. Unfortunately, tumor cells can secrete immunosuppressor factors ( such as il - 10, tgf - p, vegf ) to interfere with dc maturation and function. to overcome tumor - mediated inhibition of dc maturation and function in vivo, immunopotentiating cytokines ( such as il - 7, il - 12 ) were used for gene - modification of dc, which has proven to be an efficient way to treat cancer in animal models

    雖然有直接瘤內注射dc誘導抗腫瘤免疫效應的報道，但腫瘤局部往往是一個處于高度免疫抑制狀態的微環境，腫瘤細胞分泌的可溶性介質（如ill 、 tgf卜vegf等）能抑制dc的分化成熟，下調dc表面共刺激分子的表達和iliz的分泌，從而抑制dc的抗原提呈功能，亦對t細胞功能有顯著的抑制作用。
  16. Activated dc cells promote the antigen to repress tumor metastasis, the breakdown product of cancer cellular necrosis also exciting immunologic system

    活化dc細胞促進抗原呈抑制腫瘤轉移，壞死癌細胞分解產物刺激增強免役系統
  17. Interferon - is an antiviral cytokine produced by activated t cell and nk cell. it upregulated mhc ii antigen expression, influenced the cellular and humoral immune response and has pleiotropic regulatory effects on immune system. one gene was amplified by reverse transcription - polymerase chain reaction ( rt - pcr ) in splenocytes which was stimulated with cona for 24 hours

    -干擾素（ interferon - ， ifn - ）主要由活化的t細胞及nk細胞產生，具有抗病毒作用，也具有上調mhc （ majorhistocompatibilitycomplex ， mhc ）類抗原分子的表達等作用，是影響機體細胞免疫和體液免疫反應的一類具有多種調節效應的細胞因子。
  18. In the second trial, this modified discontinuous percoll gradient centrifugation method was introduced to isolate spermatids from the semen of fifteen male infertile patients. then the effect was identified by wright - giemsa stain, flow cytometry analysis, immunocytochemistry and fluorescence in situ hybridization ( fish ). similary, the 22 % percoll fraction contained mostly haploid cells [ ( 91. 85 ? 5. 18 ) % ] ( p < 0. 005 ) and the mean density in this fraction was ( 1. 010 ? 0. 786 ) x 105 / ml

    C法，對15例各種類型不育患者的精液細胞進行分離，並利用瑞姬染色法、流式細胞術、免疫細胞化學和熒光原位雜交oisffi等方法，從細胞形態特徵、 dna倍體、細胞表面標i己與分化抗原，以及原位雜交信號的數目和位置結合細胞核特有的形態等方面加以鑒定。
  19. Cd226, also named platelet and t cell activation antigen 1 ( ptal ), was discovered by burns in 1985. pta1 mainly expressed on activated t cell, nk cell, megakaryocyte and platelet. previous study indicated that il - 2, tnf - a and pma could upregulate the expression of pta1 on t lymphocytes and tgf - p down - regulate its expression

    Cd226又稱為血小板和t細胞活化抗原1 （ plateletandtcellactivationantigen1 ， pta1 ） ，最早在1985年由bums等發現，主要表達于活化t細胞、 nk細胞、巨核及血小板譜系，參與t細胞的活化與分化以及血小板的活化和聚集。
  20. On the other hand, the expression is repressed by the proto - oncogenes n - myc and c - myc, and in some cases the expression is also repressed by testosterone or dihydrotestosterone ( androgen ) at mrna level infering from all the references that can be obtained, the functions of ndrg family may be involved in cellular differentiation events > maintaining the balance of cell redox potential ( in oxidative stress condition or biological conversion process ), or counteracting cell malignant transformation, and so on

    綜合己有的文獻，推測ndrg家族可能參與細胞生長分化、維持細胞氧化還原電勢平衡（氧化應激或生物轉化） 、阻止腫瘤細胞惡化等。因此，研究其在細胞中的具體功能以及可能的信號通路將具有非常重要的意義。深人研究ndrgz在體內的組織細胞和亞細胞水平分佈特點及其功能，需要高效價和高特異性的ndrgz抗體。
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