細胞抗原受體 的英文怎麼說
中文拼音 [xìbāokàngyuánshòutǐ]
細胞抗原受體
英文
b cell antigen receptorb- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 原 : Ⅰ形容詞1 (最初的; 原來的) primary; original; former 2 (沒有加工的) unprocessed; raw Ⅱ動詞(原...
- 體 : 體構詞成分。
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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On the other hand, there is substanial evidences tha dcs mediate tolerane. the gm - csf - stbolated mouse bone mwderived mhc class ii + dc progendors tha are deficient in cell surface erpression of the costbolatory molecules b7 - l and b7 - 2 can induce alloanginspecific t ceil anergy in vbo. systendc adchstraion of these donor - derived dc progendors to recipients intravenously 7 days before transplantation prolonged the median graft survival tane from 9. 5 days to 22 days wbout additional twnosuppressions in a mouse cardinc twlanation model
1995年, lul等報道表面缺乏共刺激分子,特別是缺乏cd80 ( b7 - 1 )和cd86 ( b7 - 2 )的未成熟型dc能在體外誘導同種抗原特異性的t細胞無能,而對dc的適當處理能夠使未成熟型dc潛在的耐受原性得以放大和增強,使得dc在誘導免疫耐受中具有相當重要的作用及潛在的應用價值。Activation of the complement may lead to killing of the microorganisms by direct lysis effect of complement system or the phagocytosis by the enhancement of the attachment of microbes to the phagocyte ( opsonization ). low serun concentrations of mbl in man is the basis for a common opsonic defect associated with recurrent infection
它可選擇性識別多種病原體表面的糖結構,以不依賴抗體和c1q的方式激活補體,發揮溶破和間接調理功能,還能與吞噬細胞膠凝素受體結合而起直接調理作用。Covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation including molecular structure and assembly of mhc molecules, the biology of cytokines, leukocyte - endothelial interactions, and the pathogenesis of immunologically mediated diseases
課程涵蓋免疫系統的細胞和組織,淋巴球的發育過程,抗原受體的結構和功能,抗原反應過程的細胞生物學以及抗原的呈現,其中包括mhc分子的結構與組合,細胞激素的生物學,白血球和內皮組織的互動關系,以及免疫相關疾病的致病機轉。Presl ( 20 - 47 ) is one of the important epitope of hbsag, which has been pointed out to have relationship with infection of hbv. humanized antibody against presl with high affinity is a new way to block hbv
乙肝病毒表面抗原pres1 ( 20 - 47 )表位是重要的乙肝病毒( hbv )表位,其識別肝細胞受體,並與hbv侵染人肝細胞有關。At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是,學者們發現這一療法存在著如下的缺陷:單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用,且有誘導免疫耐受的潛在危險,有時反而會促進腫瘤的生長;事先需對患者的hla單倍型進行鑒定,以確定ctl表位與hla單倍型是否匹配,目前尚缺乏能與所有hla單倍型相匹配的ctl表位,從而限制了這一療法的應用;這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞,但對腫瘤細胞的殺傷能力較弱:這種l表位抗原肽缺乏cd4汀h細胞相關的表位,因此,不能誘導有效的th細胞免疫應答。Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc
而t細胞的活化除需要t細胞受體( tcr )與抗原呈遞細胞( antigenpresentingcell , apc )表面的抗原肽- mhc復合物結合所形成的第一信號外,還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號(亦稱第二信號或輔助刺激信號, costimulatorysignal )的參與。Methods employed to prepare vaccine include rumor cells genetically modified with cytokines, costimulatory molecules and tumor antigenic peptides, dendritic cells ( dc ) primed with tumor antigens in vitro or genetically modified with tumor antigens, or fusion of tumor cells with antigen presenting cells ( apc )
現有的比較受到關注的制備腫瘤疫苗的方法有各種細胞因子、共刺激分子、腫瘤抗原肽等基因修飾的腫瘤細胞疫苗;體外抗原致敏的或腫瘤抗原肽基因修飾的樹突狀細胞疫苗;腫瘤細胞與抗原遞呈細胞融合疫苗等。By pulling receptors away from their surface membrane during signaling, t cells can prevent themselves from being lethally overstimulated by too much antigen
在溝通過程中, t細胞會將受體抽離細胞膜表面,以避免因受到過多抗原的刺激而死於非命。A positive correlation of scc ag with the percentage of body surface and psoriasis area and severity index ( pasi ) score was found
鱗狀細胞癌抗原與身體表面受侵犯的百分比及乾癬區域嚴重度指標呈現正相關性。To mark out the pattern of ccr5 expression on antigen - presenting cells apcs in hiv infection
鑒定趨化因子受體第5號在感染愛滋病病毒者的呈抗原細胞上的表現模式To mark out the pattern of ccr5 expression on antigen - presenting cells ( apcs ) in hiv infection
鑒定趨化因子受體第5號在感染愛滋病病毒者的呈抗原細胞上的表現模式;A variety of biological components ( including enzymes, antibodies, antigens, nucleic acids, isolated receptors, whole cells, microorganisms, and plant or animal tissues ) have been applied to sensing system
很多種類的生物組分(包括酶、抗體、抗原、核酸、獨立受體、完整的細胞、微生物、動植物組織)已被用於這類傳感體系,構成各種生物傳感器。N - acetylcysteine is the acetylation of l - cysteine as the donor of sulfhydrylgruppe ( - sh ), not only has the great antioxidation, but also supplies the reduced glutathione in the body efficiently, and pretects the cell not to be injuried. the preventive effective of n - acetylcysteine against acute lung injury has been supported by the animal experiment and clinic research
N -乙酰半胱氨酸是l -半胱氨酸的乙酰化物,作為巰基的供體,不僅具有強大的抗氧化作用,還能有效補充機體內降低的還原型谷胱苷肽,保護細胞免受損傷,其對急性肺損傷的防治作用已獲得動物實驗和臨床研究結果的支持。B cell antigen receptorb
細胞抗原受體In the first part, we observed the changes of expressions of type i receptor of il - 1 in the rat and mouse brain after intraperitoneally administration of different kinds and doses antigens respectively. in the second part including two experiments we cloned rat il - 6r ' s genes by pcr, expressed them in e. coli dh5 a and cos - 7 cell, and produced il - 6r ' s polyclonal antibody which is proved having more high liter, affinity and specificity 1
第一部分採用不同種類和劑量的抗原刺激,分兩個實驗,觀察了大、小鼠腦內il - 1的i型受體表達的變化,探討了腦內參與免疫調控的核團和細胞類型;第二部分分兩個實驗,運用pcr技術克隆了大鼠il - 6r的基因並進行了原核和真核表達,制備了特異性高、親和力強和較高效價的抗il - 6r多克隆抗體,為進一步進行il - 6r的研究奠定了基礎。However, dna damage has been ruled out as the prerequisite for alkylating agents - induced mutagenesis. for example, somatic hypermutation, which occurred around the variable region in the immunoglobin gene of b cells, is driven by antigen activation not by dna damage and is considered a kind of active mutation
但是dna損傷並不是引起突變的必要條件,一個典型的例子就是發生在b淋巴細胞的免疫球蛋白( ig )可變區基因上的「體細胞超突變( somatichyermutation ) 」 ,是由表面抗原受體而不是dna損傷驅動的主動突變。Serial mixed lymphocyte assays demonstrated suppression of the recipient immune response to the donor antigen after pretreatment, but no additional neuroregenerative effect of donor alloantigen pretreatment
而混合淋巴細胞檢測則表明,預處理后受體對供體抗原的免疫反應被抑制,但供體的同種異體抗原對神經再生無促進作用。T cell antigen receptort
細胞抗原受體To activate t cells, one receptor responds to a specific foreign invader, or antigen, and another, cd28, signals a green light for an immune response
一般t細胞的活化,除了要有一個特定外來物(抗原)與細胞表面受體結合,還需要另一個受體蛋白cd28發出免疫反應的綠燈信號。Howeer, many pathogens lie inside cells where they aoid being attacked because the antibodies can ' t get to them
但仍有很多病原體隱蔽在細胞內部因抗體達不到而免受攻擊。分享友人