細胞核毒性的 的英文怎麼說
中文拼音 [xìbāohédúxìngde]
細胞核毒性的
英文
caryotoxic- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 核 : 核構詞成分。
- 毒 : Ⅰ名詞1 (對生物體有害的性質或物質; 毒物) poison; toxin 2 (毒品) drug; narcotics 3 (姓氏) a s...
- 性 : Ⅰ名詞1 (性格) nature; character; disposition 2 (性能; 性質) property; quality 3 (性別) sex ...
- 的 : 4次方是 The fourth power of 2 is direction
- 細胞核 : nucleus; caryon; cyteblast; cell nucleus
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
- 毒性 : [藥理學] toxicity; virulence; poisonousness毒性測定 toxicity test
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It refers to the release of the viral genome from its protective capsid to enable the nucleic acid to be transported within the cell and transcribed to form new progeny virions
它指的是將病毒基因組從它的保護性衣殼中釋放出來,使核酸能在細胞內轉運並能轉錄以形成新的子代病毒。We found nuclear deformation lymphocytes with increased heterochromatin and impaired thymus epithelium cells with increased lysosomes and deformation of mitochondrias. ( 4 ) effects on mouse liver of so2 challenge : so2 can cause significant liver injury. he staining showed several kinds of necrosis of liver including spot necrosis, focal necrosis and submassive necrosis infiltrated with lymphocytes, monocytes, few neutrophils and eosinophils ; tem observation showed fatty degeneration with dispersion of fatty droplets and dilation of rough endoplasmic reticulums, acid degeneration with significant hyperplasia of mitochondrias, necrosis of hepatocytes with karyorrhexis and other organelles losing their normal structure
( 4 )二氧化硫染毒對小鼠肝臟的組織學結構有明顯影響,可引起肝臟點狀壞死、灶狀壞死甚至片狀壞死,伴隨不同程度的炎性細胞浸潤;透射電鏡觀察發現二氧化硫可引起肝細胞脂肪變性、嗜酸性顆粒變和壞死,脂肪變肝細胞中可見大小不等的脂滴存在,嗜酸性顆粒變肝細胞中可見線粒體明顯增生,壞死肝細胞可見細胞核結構破壞,細胞器減少,細胞膜不完整。Porcine transmissible gastroenteristis is an importan contagious disease endangering the development of swine. in other to establish a rapid diagnosis method and provide effective immunogenic products, the nucleoprotein ( n ) gene of porcine transmissible gastroenteristis virus ( tgev ) was cloned. expressed and its expressed product was purified
為建立對豬傳染性胃腸炎快速有效的診斷方法,並試圖在預防上提供有效的免疫制劑,本論文首次在我國對豬傳染性胃腸炎病毒核衣殼蛋白基因進行了克隆、鑒定、表達及重組核蛋白的純化;並在細胞上對重組核衣殼蛋白抗體的中和效力進行了測定。Dna damages caused by so2 and lead acetate were studied with the single cell microgel electrophoresis technique ( or comet assay ) in order to confirm the damaging degree of lead ( as an important component of atmosphere particle matter ) on dna from male mice exposed to so2. the migrating distances of dna of brain, lung, spleen and kidney cells of mice increased significantly, compared to the control group under conditions of single and combined poisoning of so2 ( 42mg / m3 ) and lead acetate ( 0. 2 % ), and lead could strengthen dna damage degree by so2 in nuclear dna of brain, kidney, spleen cells. damaging degree of so2 on nuclear dna of lung cell of mice was more severe than that of lead
為了明確大氣顆粒物中的重要組分? ?鉛在二氧化硫所致dna損傷中的作用程度,利用單細胞凝膠電泳技術( singlecellgelelectrophoresis , scge ,或稱彗星實驗, cometassay )研究了鉛與二氧化硫的聯合污染,結果表明在42mg m ~ 3so _ 2和0 . 2醋酸摘要一abstract鉛單獨及聯合染毒條件下,小鼠腦、肺、腎、脾細胞dna遷移距離均比對照顯著增加;鉛加劇了50 :對腦、腎、脾細胞核dna的損傷程度; 50 :對肺細胞核dna的損傷程度要比鉛的損傷大,小鼠肺細胞核dna遷移距離在50 :和醋酸鉛聯合作用組與醋酸鉛單獨作用組間有極顯著性差異( p < 0 . 01 ) ,而與502單獨作用組間沒有顯著性差異。Containing many t cell epi - positions and neutralizing antibody epi - positions, the core protein region and envelope protein 2 of hepatitis c virus ( hcv ) structural protein may induce protective immunity responsion in body
丙型肝炎病毒( hepatitiscvirus , hcv )結構蛋白的核心蛋白( c )和包膜蛋白2 ( e2 )含有多個t細胞表位和中和抗體表位,可誘導機體產生保護性免疫應答。Differential diagnosis included cerebral toxoplasmosis, cytomegalovirus ( cmv ) encephalitis, primary cns lymphoma, progressive multifocal leukoencephalopathy, fungal abcess due to candida, aspergillus, or cryptococcus, varicella - zoster virus encephalitis or vasculitis, herpes simplex encephalitis, tuberculosis ( m. tuberculosis ), and kaposi ' s sarcoma
其它的診斷包括:腦弓形體病,巨細胞病毒( cmv )型腦炎,原發中樞系統淋巴瘤,漸進性多灶性腦白質病,假絲酵母菌,麴菌或隱球菌所致真菌性膿腫,水痘帶狀病毒型腦炎或脈管炎,單純皰疹腦炎,肺結核(多發性結核) ,和卡波西肉瘤。Hi our study, dendritic cells ( dcs ) were derived from the cultivation of peripheral blood monocytes in vitro successfully. then to observe whether dcs transfected with carcinoembryonic antigen ( cea ) - vaccinia recombinant virus ( rv - cea ) can induces cytotoxic t lymphocyte - mediated cea - specific immunity in vitro
體外成功地完成了cd14 +單核細胞來源的樹突狀細胞( dc )的培養,並進一步研究人癌胚抗原重組痘苗病毒( rv - cea )轉染dc后體外誘導的cea特異性細胞免疫。Detection of genotoxicity in petrochemical wastewater using micronucleus test technique of vicia fabra root tip cells
蠶豆根尖細胞微核技術測試石油化工廢水的生物毒性Salmonella typhimuriwn, one of the invasive bacterial species, can be attenuated without loss of invasiveness and thus used for delivery of eukaryotic expression vectors into host cells in vivo. the recombinant plasmid containing the target gene is released inside the host cells and gain entry into the nucleus, resulting in expression of encoded antigens and subsequent induction of humoral and cellular immune responses
沙門氏菌( salmonellatyphimurium )是一種較為常見的侵襲性胞內菌,通過基因工程方法減毒后對宿主致病性顯著降低,但仍保留良好的侵襲力,可直接將真核表達質粒攜帶進入動物細胞內表達相應的蛋白而誘導特異性的免疫應答反應。Hydroxyapatite poly - l - lactide for cytotoxicity of human bone marrow karyote
左旋聚乳酸對人骨髓有核細胞毒性的實驗The changes of above show that the damage to the chicken embryo caused by the chicken parvoviruses were widly. the pathogeny of infectious stunting syndrom was prolifirated in cells nucleus, it was a dna virus
以上變化說明了分離病毒對機體損傷的廣泛性。核內包涵體的出現進一步說明,雞傳染性生長障礙綜合征的病原在細胞核內增殖,為dna病毒。Dna and rna dot blotting revealed that the f gene was transcribed into mrna in the vero cells. there was expression of the f protein as shown by indirect immunofluorescent assay. the expression began at 48h post - infection and increased thereafter, as indicated by elisa
將真核表達質粒pcdna3 - f高壓電轉化dam和phop基因雙突變的減毒鼠傷寒沙門氏菌zj111株( zj111 / pcdan3 - f ) ,並直接轉染vero細胞,分別提取細胞總dna和總rna , dig標記探針均可檢測到陽性雜交信號。In young chickens aev induces paralysis, ataxia and muscular dystrophy, while in older chickens, infection is usually subclinical, resulting in a decline in egg production and hatchability. infectivity was shown to remain unaffected by chloroform, low ph, pepsin, trypsin and deoxyribonuclease. magnesium cations were shown to stabilise preparations of the virus against heat inactivation. the buoyant density of virions are 1. 31g / ml. the diameter of the virion was estimated to be 22 to 30nm. the aev can be adapted to grow in chicken embryo. the inability of aev to grow effeciently in most cell cultures
幼雞感染該病毒后,引起麻痹、頭頸震顫甚至共濟失調,而成雞常呈亞臨床感染或導致產蛋量和孵化率下降。病毒的感染性不受氯仿、低ph 、胃蛋白酶、胰酶和脫氧核糖核酸酶的影響,鎂離子可增強病毒對熱的穩定性,病毒的浮密度為1 . 31g ml ,直徑為22 - 30nm ,該病毒主要在雞胚中增殖,在大多數細胞培養物中不生長。Mutated plasmid was transformed into e. coli tg1 cells to produce engineered peptide, then the peptide was purified by cm sepharose ion - exchange column. in vitro bactericidal assay and drug withdrawal were used to identify the bioactivity of the engineered peptide. the planar lipid bilayer membrane was used to assay the electrophysiology of the engineered peptide. toxicity studies on mammalian cells were used to assay the toxicity of the engineered peptide
將重組質粒轉化入大腸桿菌tgi工程菌中,生產構建的工程多膚,離子交換純化后獲得工程多膚初步純化產物,體外抗菌試驗、藥物撤離試驗檢測工程多膚的抗菌活性,在人工脂質膜上測定其形成離子通道的特性以初步研究抗菌機理, ?並觀察其對真核細胞的毒性作用。The viral nucleic acid contains information necessary for programming the infected host cell to synthesize virus - specific macromolecules required for the production of viral progeny
病毒的核酸含有使感染細胞合成子代病毒所需的病毒特異性大分子的所有必需的信息There were significant differences rert0. 05 ) in number of cd4 + t cells in peripheral blood lymphocytes between group a and group d at l4, 47 and 54 days of pi, group a was higher than group d. there were sighficant differences ( prt0. 05 ) in number of cd4 + t cel1s in peripheral blood lymphocytes between group b and group d at 28 and 47 days of pi, group b was higher than group d. there were significant differences ( pwt0. 05 ) in number of cd4 + t ceils in peripherai blood lymphocytes between group c and group d at 28 days of pi, group c was higher than group d. there were significant differences ( prt0. 05 ) in number of cd8 + t cells in peripheral biood iymphocytes between group a and group d at l4 days of pi, group a was nigher than group d. there were significant differences ( p < 0. 05 ) in number of cd8 + t cells in peripheral b1ood lymphocytes between group b and group d at l4 days of p [, group b
C組與d組小員外周血cd4 ~ + t細胞數量在首免后28d與對照組比較,差異顯著( p 0 . 05 ) , c組小員外周血cd4 ~ + t細胞數量明顯高於d組。 a組與d組小鼠外周血cd8 ~ + t細胞數量在首免后第14d出現顯著差異( p 0 . 05 ) ,博士學位論文豬輪狀病毒和傳染性胃腸炎病毒核酸免疫的研究2002年12月a組小鼠外周血cds 」 t細胞數量明顯高於d組。 b組與d組小鼠外周血cds 」 t細胞數量在首免后第14d出現顯著差異( p 0It is thought that extracellular gsh protects the cells from oxidants released by inflammatory cells whilst intracellular gsh neutralizes the ros produced as a result of normal cell metabolism, as well as detoxifying xenobiotics ( 4 )
研究者認為細胞外的谷胱甘肽可保戶細胞免受發炎細胞所釋放氧化劑的攻擊,而細胞內的谷胱甘肽可中和正常細胞代謝作用以及共棲生物解毒作用所產生的具反應性氧核素。Objective, clone tissue - type plasminogen activator ( t - pa ) gene and construct a new kind of recombinant vector containing human tissue - type plasminogon activator ( t - pa ) cnda neither cytotoxiaty nor actovating prot - oncogenes
目的:克隆組織纖溶酶原激活物( t - pa )基因並構建一種無細胞毒性、不激活原癌基因的真核表達的pcdna3 . 1 ( + ) / t - pa質粒載體。( 2 ) effects on mouse spleen of so2 challenge : we found significant apoptotic changes of mouse spleen through tem observation and dna electrophoresis analysis and flow cytometric analysis. we found condensed, marginating, half - moon like apoptotic lymphocytes both in white pulp and red pulp ; we found significant dna degradation with dna ladders from the dna electrophoresis analysis in the 168 mg / m3 so2 treated group ; we also found marked increase of apoptotic rate between 168 mg / m3 so2 treated group and control group from the flow cytometric analysis
( 2 )二氧化硫吸入可引起小鼠脾臟細胞出現明顯的凋亡改變,紅髓區和白髓區淋巴細胞出現核固縮,染色質凝聚、邊集; dna凝膠電泳分析發現168mg m ~ 3二氧化硫染毒組出現典型的dna梯形條帶;流式細胞分析也發現高劑量染毒組的小鼠脾細胞凋亡率增加,並且與對照組相比有顯著性差異, p 0 . 05 。It is known from studies using brefeldin a ( bfa ) that disruption of tgn can block the cytotoxicity of ricin, suggesting that the intracellular compartment may be an important part of the uptake pathway. ricin enters the cells by receptor - mediated endocytosis, followed by translocation across the membranes of intracellular organelles. in this study, a trans - golgi retention peptide signal yqrl was fused to the c - terminus of ricin a chain ( rta ) by polymerase chain reaction
本實驗為重點研究反式高爾基體在毒素細胞內轉運過程中的作用,我們設計了一個反式高爾基體的靶向信號肽基因yqrl ( tyr - gln - arg - leu )連接在rta分子的羧基端,用原核表達蛋白體系,純化並測定rta - yqrl與rta蛋白對hela (人宮頸癌細胞) , wish (人羊膜上皮細胞) , skov - 3 (人卵巢癌細胞)三種細胞的毒性作用。分享友人