組異肽 的英文怎麼說
中文拼音 [zǔyìtài]
組異肽
英文
peptide histidine isoleucine-
Female mice serum and vaginal secretion antibodies, their fertility and the pathological changes were determined. on the other hand, the effects of the anti - serum against synthetic peptide on the sperm - egg interaction during ivf and the location of p3 peptide in sperm were watched. the main results and conclusions were as follows : 1 ) the new antigen p3 peptide which harvested from the 430a peptide synthesizer were verified by the mass spectrograph and hplc, that the ratio of mass / charge of the synthetic peptide was equal to the molecular weight in theory and its purity was above 95 %
本研究的主要結果和結論如下:一、經抗原分子設計,在430a自動肽合成儀上合成的新抗原p3 ,經質譜儀分析證明其荷質比與理論一致;純化后,其純度大於95 ;將新抗原與klh偶連后免疫小鼠,經westernblot證實其誘導的特異性抗體可識別小鼠、大鼠、人睪丸組織中分子量約為22kd和55kd左右的蛋白質。This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗,將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合,獲得新抗原- 35肽序列;並在合成、純化後分別與弗氏佐劑、免疫刺激復合物( iscoms )混合后免疫不同遺傳背景的雌性小鼠,觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變:以及在ivf下,新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。Injected group, 0. 1 % saccharin ( 1. 5 ~ 2ml / rat, in 5min ) intraoral infused group and cta group. the expression of endogenous leucin - enkephalin ( lek ) in the rat brain was observed and 5 parts of the thalamus including laterodorsal thalamic nucleus ( ld ), lateral part of mediodorsal thalamic nucleus ( mdl ), ventroposterolateral thalamic nucleus ( vpl ), ventroposteromedial thalamic nucleus ( vpm ) and reticular thalamic nucleus ( rt ) were comparatively researched before and after the acquisition of cta applying lek - immunocytochemistry. in behavioral experiment, 18 adult male sd rats were divided into normal cta group ( control ) and 2 naloxone i. p
為探討cta形成過程中enk的作用,本實驗用成年雄性sd大鼠35隻,分為空白對照組、生理鹽水( 2體重)腹腔注射組、 0 . 15mlicl溶液( 2體重)腹腔注射組、 0 . 1糖精溶液口腔灌流組( 1 . 5 - 2ml只, 5min )和cta建立組,採用免疫細胞化學方法,觀察了亮腦啡肽( lek )陽性神經元在大鼠腦內的分佈情況,並比較了各組大鼠丘腦外側背核( ld ) 、丘腦內側背核外側部( mdl ) 、丘腦腹后外側核( vpl ) 、丘腦腹后內側核( vpm )以及丘腦網狀核( rt )等5個腦區內lek表達水平的差異;另外將成年雄性sd大鼠18隻,分為正常cta建立組以及在cta建立前或cta建立后阿片受體拮抗劑納洛酮( 2mg kg體重)腹腔注射組,對內源性阿片樣物質對于cta建立和保持的影響進行了行為學研究。This sequence emergences fourteen times from 1000 ests library indicts that it is a middle affluently gene in cdna library. the cdna of 634 basepairs contains an open reading frame of 339 nucleotides encoding a novel nonspecific lipid transfer protein. the first 23 amino acids constitute the putative signal peptide, characteristic for targeting to the secretory pathway
測得th - nsltp序列全長為634bp ,含有一個非特異性脂轉移蛋白與植物耐逆性的相關性研究編碼112個氨基酸的閱讀框架, n端的23個氨基酸組成一段信號肽序列,表明它可能和分泌有關。Purposes : enhancement of insulin secretion from the islet b cells is a principal goal for treatment of patients with type 2 diabetes. some gastrointestinal hormones are associated with insulin secretion
目的:胰高血糖素樣肽- 1 ( glucagon - likepeptide - 1 , glp - 1 )是一種組織特異性的胃腸道激素,主要由回腸末端l細胞、胰腺內分泌部a細胞以及神經細胞合成和分泌。Results the levels of endotoxin, leukocyte, mda and sod were all signifificantly higher than control group, while, the level of glutathione ( gsh ) was much lower in experimental group ( p < 0. 01 )
結果模型組內毒素、肺勻漿脂質過氧化物,以及白細胞計數均明顯增高;而還原谷胱甘肽( gsh )明顯降低,與對照組比差異有顯著性( p < 0 . 05 ) 。Objective : laminin 5 is a hetertrimeric glycoprotein with a strong adhesive function consisting of three polypeptide chains ( 03, f ^ y 2 ) that is secreted by keratinocytes
目的: ln - 5是一個由三條多肽鏈( 3 、 3 、 2 )組成的異三聚體的糖蛋白,由角質形成細胞產生的,具有強大粘附功能。The human total rna was extracted from the foetal liver tissue sample of spontaneous abortion. mrna was separated and purified from total rna. apoe3 cdna was amplified by rt - pcr with a signal or without a signal sequence
從正常流產胎幾肝組織中提取總rna ,分離純化mrna ,以mrna為模板, rt pcr特異擴增帶信號肽和不帶信號肽的人apoescdna片段,將apoeThis study was to investigate the effects of sulfur dioxide inhalation at different concentrations on some glutathione - related enzymes such as glutathione s - transferase ( gst ), glucose 6 - phosphate dehydrogenase ( g6pd ) and glutathione reductase ( gred ) in brain, lung, heart, liver, kidney and spleen of mice by the technology of biochemical toxicology. the results were showed as follows, so2 exposure at different concentrations caused the changes of glutathione redox system. moreover, the activities of antioxidative enzymes and the contents of reduced glutathione ( gsh ) were decreased significantly in different tissues at higher concentrations of soa
本研究利用生化毒理學技術研究了不同濃度二氧化硫吸入( 22 2mg m ~ 3 , 64 3mg m ~ 3 , 148 23mg m ~ 3 )對純系昆明小鼠腦、肺、心、肝、腎、脾六種組織的谷胱甘肽還原酶( glutathionereductase , gred ) 、谷胱甘肽硫轉移酶( glutathiones - transferase , gst )和葡萄糖- 6 -磷酸脫氫酶( glucose6 - phosphmedehydrogenase , g6pd )活性的影響,結果表明so _ 2吸入使小鼠不同組織的谷胱甘肽氧化還原系統發生了改變,表現為隨著so _ 2吸入濃度的增加,該系統中的抗氧化酶活性的顯著變化和抗氧化物質水平的顯著降低,且存在著組織差異性。In a preferred embodiment, a. alpha. - hydroxy carboxylic acid with a specific chiral configuration is linked by an amide linkage to a. alpha. - amino acid specific with a specific chiral configuration or linked by an amide linkage to a peptide made up of. alpha. - amino acid monomers having identical chiral configurations
主要體現在,含有特定結構的-羥基羧酸與一個含特定結構的-氨基酸以氨基聯接特異結合,或與一個有相同結構的,由-氨基酸單體組成的肽以氨基聯接相連。The npr - c is a membrane - bound receptor that lacks the intracellular guanylate cyclase domains of the biologically active receptors and is therefore uncoupled with cgmp. npr - c functions as a clearance receptor by binding with and internalizing natriuretic peptides. nprs are widely and differently distributed in most tissues and can be up - or down - regulated in many pathological processes, which indicates that they have different effects on different tissue and participate in the regulation of their physiological and pathological process
正常情況下,三種受體在體內均廣泛分佈,但在不同組織中的分佈有很大差異,而且在不同病理條件下鈉尿肽受體數目還可發生上調和下調,提示鈉尿肽家族及其受體對不同組織器官的作用不同,並參與它們的生理和病理過程的調節。The expression patterns of soluble proteins, peroxidase and esterase isozymes were analysed on globular embryogenesis in tissue cultures of alfalfa, it was concluded that from embryogenic callus to globular embryo genesis h peptides emerged and disappeared orderly, the patterns of peroxidase isozyme changed dramatically, esterase isozymes changed slightly while the total enzyme activity was important to keeping the potential of somatic embryogenesis
摘要試驗在苜蓿組織培養中,對球形胚形成過程中特異蛋白質表達的模式、過氧化物酶及酯酶同工酶酶譜變化進行研究,結果表明:苜蓿組織培養中從胚性愈傷組織到球形胚發育的進程中,順序消失和出現了11種中小分子量多肽;過氧化物酶同工酶酶譜發生了顯著的變化;酯酶同工酶酶譜變化不大,但其總活力對于維持體細胞胚胎發生是必須的。Extract the total rna from human tonsil and amplify the h d - 3 specific cdna sequence using rt - pcr with two special primers based on h d - 3 amino acid sequence in genbank. then the amplified product was analyzed on a 2 % agarose gel
自人扁桃體組織提取細胞總rna后,根據genbank中編碼h d - 3成熟肽45個氨基酸的cdna序列,設計特異引物進行rt - pcr 。分享友人