翻譯后修飾 的英文怎麼說

中文拼音 [fānyìhòuxiūshì]
翻譯后修飾 英文
post-translation modification
  • 翻 : 動詞1 （變換位置; 歪倒; 反轉） turn over; turn around; reverse 2 （移動物體尋找） rummage; search...
  • 譯 : 動詞（翻譯） translate; interpret
  • 修 : Ⅰ動詞1 （修飾） embellish; decorate 2 （修理; 整治） repair; mend; overhaul 3 （寫; 編寫） write;...
  • 飾 : Ⅰ動詞1 （裝飾） decorate; adorn; dress up; polish; cover up 2 （扮演） play the role of; act the ...
  • 翻譯 : 1 （把一種語言譯成另一種語言） translate; interpret; put into ; turn into ; transcribe; render 2 ...
  1. Compared to the prokaryotic gene expressing systems and mammalian gene expressing systems, insect gene expressing systems possess the stronger ability of the transcription and post - translation processing, which also has high production. we can anticipate it will be a kind of potent effective ectogenesis eukaryotic gene expressing system

    與原核表達系統和哺乳動物細胞表達系統比較，昆蟲細胞表達系統既有較強轉錄和翻譯后加工修飾能力，又有高表達量等特點，可望成為基因產業中一種比較理想的外源真核基因表達系統。
  2. Human bone morphogenetic protein 3 is a member of tgf - b superfamily. lt can induce the differentiation of cartilage and bone tissue in mesenchymal cell. and is important to bone self - repairment and bone development during embryo morphogenesis. in addition, some other biological activities of hbmp - 3 have also been found. such as inducing development of embryo and stimulating differentiation of neural and blood cells. therefore, there is a great prospect in the use of hbmp - 3. there is trace content of hbmp - 3 in human body. it has been expressed in the expression system of eukaryotes and prokaryotes respectively, but its application is restricted because of defects in the process and modification after translation in prokaryotic cells and higher costs and lower yields existed in eukaryotic expression system

    人骨形成蛋白3 （ hbmp - 3 ）屬于tgf -超家族的一員，可以誘導間充質細胞分化為軟骨和骨，在胚胎時期骨骼發育和骨再生修復中起著重要的作用，而且對胚胎發育過程中中胚層的誘導和分化、造血組織的發育以及神經系統的發育和修復等都起著重要作用，因而hbmp - 3有廣闊的市場前景。它在人體內含量極微，盡管研究人員已經在原核細胞和真核細胞表達系統中分別進行了表達，但是由於原核表達系統缺乏翻譯后的加工修飾，真核表達系統存在成本高、產量低等特點，限制了其在臨床上的應用。
  3. In vivo, the two functional forms of rat mapllc3 with apparent mobilities of 18 and 16kda, termed lc3 - i and lc3 - ii, separately, were produced by a series of post - translational modifications including a characteristic c - terminal cleavage after the conserved glyl20 residue and this cleavage is essential for the membrane association of the 16kda rat map1lc3 protein.,

    其中18kda的map1lc3蛋白是微管相關蛋白1的輕鏈亞基，稱為lc3 - ；另一種16kda的map1lc3蛋白則是自噬體膜的必須組分，稱為lc3 - 。 lc3 -和lc3 -都是一系列翻譯后修飾的產物，其中特徵性的修飾是在保守gly120后發生的羧基端切割，此切割修飾對lc3 -定位於自噬體膜尤為重要。
  4. In vivo, the two functional forms of rat map1lc3 with apparent mobilities of 18 and 16kb, termed lc3 - i and lc3 - ii, separately, were produced by a series of post - translational modifications including a characteristic c - terminal cleavage after the conserved gly120 residue and this cleavage was essential for the membrane association of the 16kd rat mapllc3 protein

    Lc3 ?和lc3 ?都是一系列翻譯后修飾的產物，其中特徵性的修飾是在保守gly120后發生的羧基端切割，此切割修飾對lc3 -定位於自噬體膜尤為重要。我們研究發現在大鼠，小鼠和人中map1lc3主要以兩種型存在， lc3a型和lc3b型。
  5. Although the thymosin has been successfully expressed in the prokaryotic cell system, its application is restricted because of its deficiency of modification after translation

    盡管研究者已在原核細胞表達系統對胸腺肽的表達進行了研究，但由於原核表達系統缺乏翻譯后的加工修飾等缺點，限制了其應用。
  6. It was indicated that regulation of 20ahsd activity was not due to post - translational modification by either phosphorylation cycle or glycosylation, but rather at the transcription level of 20ahsd gene expression in previous research papers

    以往研究表明20 hsd活性的調節不是通過糖基化、磷酸化或去磷酸化等翻譯后修飾實現的，而是以轉錄水平的調節為主。
  7. The gpit - catalyzed reaction represents the final step in the assembly of a gpl - anchored protein, and provides the critical post - translational modification of this class of proteins that allows them to gain entry into er - derived transport vesicles for delivery to the cell surface

    Gpit催化的這一反應為gpi化蛋白生物合成的最後一步，也是關鍵的一步。此翻譯后修飾過程保證了這類蛋白質進入出自於er的轉運囊泡，再被傳送至細胞表面。
  8. Currently there are many techniques available to screen the gene expression at the transcriptional levels, such as mkna differential display and cdna microarray. although these methods can provide high - throughput information about the differential gene expression, they can

    雖然，利用mrna差異顯示技術和基因晶元技術可在轉錄水平高通量的篩選基因表達的差異，但是這些技術都不能提供轉錄后的尤其是蛋白質在翻譯后修飾的信息，而蛋白質通常是細胞內的功能執行者。
  9. The quickly developing techniques of biological mass spectrometry ( bio - ms ) in recent years realized the high throughput identification of proteins by determining the accurate mass values of trypsin - digested peptides and the randomly selected peptide sequence tags, and have been successfully used in the studies of protein interactions and post - translational modification such as the phosphorylation

    摘要近幾年快速發展起來的生物質譜技術，依靠（酶解后肽段）精確質量數測定和隨機肽序列標簽分析，實現了對蛋白質高通量的鑒定，並被成功地用於蛋白質相互作用和蛋白質磷酸化等翻譯后修飾研究。
  10. We found that there are two types of map1lc3 in rat, mouse and human, besides that, there is another type ( map1lc3c ) in human. we expressed all map1lc3 in hek293 cells respectively and found that the post translational modification of all map1lc3 is similar to yeast apg8 and rat map1lc3 identified except human lc3b. characteristic carboxyl cleavage occurred in conserved glycine of them

    在hek293細胞中分別表達這三個物種中的所有的a型、 b型以及人map1lc3c分子，發現除了人的map1lc3b外其它同源物的修飾方式與已知的酵母apg8和大鼠的lc3修飾方式相類似，均發生了羧基端的切割反應而且羧基端保守的甘氨酸是它們發生翻譯后修飾的活性位點。
  11. It has not only many advantages of the prokaryotic expression system such as growing quickly, manipulating easily, strong power to express and control foreign protein, but also the ability to make foreign protein modified in post - translation. so pichia pastoris gene expression system is more appropriate to express many eukoryotic proteins than prokaryotic system and has attracted more and more people " s attention on it

    它不僅具有原核表達系統生長快速，操作簡單，外源基因表達量大並受到嚴格調控等特點，還具有真核生物特有的蛋白質翻譯后修飾的功能，表達真核生物蛋白質具有原核表達系統無法比擬的優越性。
  12. These proteins involved in various cellular functions including carbohydrate transport and metabolism, energy production and conversion, inorganic ion transport and metabolism, amino acid transport and metabolism, posttranslational modification, protein turnover, chaperones, function unknown and not in cog most of the proteins identified are involved in energy production and conversion, carbohydrate and amino acid transport and metabolism, especially in energy production and conversion

    這些蛋白質在細胞中行使不同的功能，主要包括: 1 .糖類轉運與代謝: 2 .能量的產生與轉化; 3 .無機離子轉運與代謝: 4 .氨基酸轉運與代謝; 5 .翻譯后修飾，蛋白代謝，分子伴侶: 6 .一些未知功能的蛋白等。在鑒定的13個蛋白中大多數是與糖類和氨基酸轉運及代謝和能量的產生與轉化相關。
  13. The protein expressed by this system can be modified correctly after the translation. firstly, rna is extracted from fresh tissue of pig liver, which is amplified as the templet by two groups of primers, so the aim gene is obtained successfully

    針對ple這一真核生物的糖蛋白，本實驗選用invitrogen公司的phichiapastorismulti - copyexpressionsystem克隆表達ple ，使ple能夠得到正確的翻譯后加工和修飾。
  14. After the gst fusion proteins were processed by factor xa and were purified by gluta - thione - sepharose 4b affinity chromatography, the recombinant protein hbrp with high purification would be acquired. during the process of separation and purification, the every result which can show the location of the aim protein was monitored by 10 % sds - page. the gst fusion proteins acquired finally were examined and analyzed by the methods of western - blottin

    原核表達系統具有表達效率高，操作方便等特點，但缺乏翻譯? 3 ?后修飾，以pgex載體表達的gst hbrp融合蛋白，具有表達的蛋白穩定性好，在體外易於純化等優點，表達的gst融合蛋白可用gluthioneseph刪sc4b進一步純化一factorxa酶切與測分離，從而大量獲得hbrp重組蛋白，而且一次回收率大約在90以上。
  15. This article mainly discusses the challenges, research approaches and recent developed tools in the field of protein function prediction and the ways by which these issues change the process of drug discovery, including homology - based annotation transfer, sequence motifs and patterns, information on 3d structure, sub - cellular localization, posttranslational modifications, binding sites and functional residues, protein - protein interactions

    摘要簡述了在蛋白質功能預測領域中的研究方法和最新研發工具所面臨的挑戰，並討論蛋白質功能預測是如何改變藥物開發進展的，具體包括：基於序列同源性分析的注釋轉移、序列基元和模式增加了注釋轉移的說服力、 3d結構信息可以精煉注釋轉移、亞細胞定位、翻譯后修飾、結合位點和功能殘基、蛋白質之間的相互作用。
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