腫瘤特異性的 的英文怎麼說
中文拼音 [zhǒngliútèyìxìngde]
腫瘤特異性的
英文
tumor-specific- 腫 : Ⅰ名詞(隆起處) swelling Ⅱ動詞(突起) swell; be swollen
- 瘤 : 名詞(瘤子) tumour
- 特 : Ⅰ形容詞(特殊; 超出一般) particular; special; exceptional; unusual Ⅱ副詞1 (特別) especially; v...
- 異 : 形容詞1 (有分別; 不相同) different 2 (奇異; 特別) strange; unusual; extraordinary 3 (另外的;...
- 性 : Ⅰ名詞1 (性格) nature; character; disposition 2 (性能; 性質) property; quality 3 (性別) sex ...
- 的 : 4次方是 The fourth power of 2 is direction
- 腫瘤 : tumour; core (綿羊體內的); neoplasm; phyma
- 特異性 : distinction
- 特異 : 1 (特別優異) exceptionally good; excellent; superfine2 (特殊) peculiar; distinctive特異功能 s...
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Based on this consideration, we chose human colorectal cancer cell line ccl229 as the experimental object, down - regulating its grp94 expression by specific ribozyme targeting. we observed its effects on the biological characteristics of ccl229 and upr pathway, and gained further understand of the grp94, upr and tumor relationship
基於此,我們選擇了人大腸癌細胞株ccl229作為研究對象,通過特異性核酶打靶的方式,下調細胞中grp94的表達水平,觀察其對人大腸癌細胞某些生物學特性及upr通路的影響,加深對grp94 、 upr和腫瘤這三者間關系的了解。Nci - h1155, a human non - small - cell lung cancer line, was employed in a paclitaxel - dependent synthetic lethal screen designed to identify gene targets that specifically reduce cell iability in the presence of otherwise sublethal concentrations of paclitaxel
Nci - h1155作為一種人類非小細胞肺癌的種株,可運用其在依賴紫杉醇殺傷性藥物合成過程中設計鑒別出靶基因,從而特異性減少未達到殺傷性致死量的紫杉醇藥物作用后腫瘤細胞仍存活的數量。This work means that antibodies can be targeted to kill cancer tumours with much greater specificity giving fewer side effects
這個作用意味著抗體能靶向殺死癌癥腫瘤,並有更高的特異性更少的副作用。It still remains a question whether the rearrangements of igh come from h / rs cell or the background lymphocytes. in this study, we have detected the igh clonal correlation between the h / rs cells and the background cells, from a new aspect to study the clonality of h / rs cell and its relation with the background cells. the expression of b - cell - specific activator protein ( bsap ) was detected in hl. igh gene rearrangements were analysed by the methods including gene analysis in neoplasms tissue and micropicked cells from paraffin - embedded sections, sequencing to test the pcr product, and in situ pcr
本研究將在以往研究的基礎上,在國內率先把b細胞核反式作用因子? b細胞特異性激活蛋白( b - cell - specificactivatorprotein , bsap )應用於hl的研究,檢測hl的bsap表達,並採用石蠟刮片組織和微切割單細胞的基因分析、測序分析和間接原位pcr等方法,同步觀察分析h rs和背景淋巴細胞的igh基因克隆相關性,從又一個新視角探究chl的腫瘤性h rs細胞克隆性及與背景淋巴細胞的關系。Preparation of specific anti - tumor immune rna
特異性抗腫瘤免疫核糖核酸的提取These findings of the specific ctls epitopes in irbp and pedf may lead to improved understanding of the pathogenesis of uveitis. our study also provides a strategy to identify specific ctls epitopes within tumour antigen, which is helpful to make tumour vaccine for the patients
本研究也為尋找腫瘤抗原中具有誘導特異性ctls能力的肽片段提供了一種策略,為制備肽片段腫瘤疫苗提供了理論基礎。Scientists at newcastle university have developed a cancer fighting technology which uses ultra - violet light to activate antibodies which very specifically attack tumours
紐卡斯爾大學的科學家開發了一種對抗癌癥的新技術,這種技術是用紫外光激活能特異性攻擊腫瘤的抗體。In contrast, most mature somatic cells in human tissues express undetectable or low telomerase activity, implying the existence of a stringent and negative regulatory mechanism. in this study, we report the effects of cisplatin on telomerase activity in human ovarian cancer cells. the special relationship between activity and cancer has a important application value
順鉑( ddp )是卵巢癌化療中最有效的基礎藥物之一,它是一種類烷化劑的抗腫瘤藥物,為細胞周期非特異性藥物,可作用細胞周期的任一時相,利於臨床的聯合用藥,但由於ddp的諸多毒副作用及卵巢癌細胞易產生對其耐藥性,常使化療效果不滿意。Mechanism of apoptin - induced apoptosis of human lymphoma cells u
腫瘤特異性凋亡基因誘導人淋巴瘤細胞凋亡的機制Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用, t細胞在發揮抗瘤效應(分泌細胞因子和直接殺傷)之前必須先經過活化,體內專職抗原提呈細胞( apc )細胞並使其活化,樹突狀細胞( dendriticcell , dc )為t細胞的激活提供雙重信號, t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后,通過tcr - cd3復合體傳遞抗原特異性識別信號(第一信號) ,以cd28為主的t細胞表面輔佐分子識別dc表面b7分子,傳遞非特異性協同刺激信號(第二信號) ,在機體抗腫瘤免疫應答中處于核心地位。Focus on research work and clinical studies in musculoskeletal oncology, especially about mechanism and biological therapy of osteosarcoma, such as proteomics studies of osteosarcoma, prospective control study of osteosarcoma, registration system of musculoskeletal oncology and genic tests about the familial inheritance osteoenchondroma, etc
擬開展《骨肉瘤特異性相關抗原的蛋白質組學研究》 、 《骨肉瘤多中心前瞻性隨機對照研究》 、 《骨與軟組織腫瘤注冊-會診-隨訪登記系統》 、 《多發性骨軟骨瘤家族遺傳性基因的檢測》等課題的相關研究工作,承擔國家、省級和市級重大項目等課題的申報。Objective : in most t eel ] malignancies, there are t cell receptors ( tcr ) expressed on the surface of the tumor cells
目的:大多數t細胞腫瘤表面有tcr獨特型抗原,可作為腫瘤特異性抗原用於免疫治療。3, the effect of k562 cell lines supernatant on no production by pbmc was investigated using the specific immunofluorescence probe daf - 2da. the results showed that the k562 cell lines supernatant could promote the no production by pbmc. further study found all the activated pbmc ( cd69 + ) produced no, while not all the no positive pbmc were activated
利用daf - 2da作為細胞內no特異性的熒光探針,研究了k562上清對pbmc產生no的影響,國內未見類似報導,發現腫瘤上清能促進pbmc細胞no的產生,進一步發現活化的細胞( cd69 + )均產生no ,而no陽性的細胞不一定活化的。Conclusion : apoptotic - tumor - cell - loaded dc induced maturation by cd40mab could efficiently induce the activation and proliferation of tumor specific ctl, and the combination of il - 2, il - 15, cd28mab was a very powerful method to expand antigen specific ctl in vitro
結論: cd40mab激發的凋亡腫瘤細胞負載dc在cd28mab 、 ilj和il上的聯合作用下可有效激活和擴增腫瘤特異性cth 。Ascribed to the discoveries of many tumor specific / associated antigens ( tsas / taas ) and the unique / excellent properties of antibody, the antibody - mediated targeting therapy of tumor persistently attracts worldwide attentions
由於許多腫瘤特異性抗原或相關抗原被發現以及抗體具有獨特而優越的性能,抗體介導的腫瘤靶向治療一直受到廣泛關注。Filamentous bacteriophage displayed tumor - specific antigen epitope mage - a1 induced cellular immune in mice
展示腫瘤特異性抗原表位的噬菌體在小鼠體內引起的細胞免疫變化A method of predicting human tumor peculiar promoter is introduced. by using transcriptional factor binding sites, this technique can receive a result well and truly
摘要本文介紹了一種利用轉錄因子結合位元點應用計算機技術對人類腫瘤特異性啟動子進行預測的方法。實驗結果證明該方法具有較高的準確性。On the other hand, the expression is repressed by the proto - oncogenes n - myc and c - myc, and in some cases the expression is also repressed by testosterone or dihydrotestosterone ( androgen ) at mrna level infering from all the references that can be obtained, the functions of ndrg family may be involved in cellular differentiation events > maintaining the balance of cell redox potential ( in oxidative stress condition or biological conversion process ), or counteracting cell malignant transformation, and so on
綜合己有的文獻,推測ndrg家族可能參與細胞生長分化、維持細胞氧化還原電勢平衡(氧化應激或生物轉化) 、阻止腫瘤細胞惡化等。因此,研究其在細胞中的具體功能以及可能的信號通路將具有非常重要的意義。深人研究ndrgz在體內的組織細胞和亞細胞水平分佈特點及其功能,需要高效價和高特異性的ndrgz抗體。The trial ' s preliminary results indicate the vaccine was associated with tumor - specific immune response in patients with recurrent, high - grade glioma
研究結果初步顯示疫苗可使復發的惡性膠質瘤患者產生腫瘤特異性免疫反應。Positron emission tomography ( pet ) is the functional imaging equipment with good specificity among the modern nuclear medicine instruments. it can make the noninvasive diagnosis of coronary artery disease ( cad ), brain disease and tumor in their early changes. therefore, it plays a very important role in the field of modern medicine
正電子發射斷層掃描儀( pet )是核醫學儀器中一種具有較高特異性的功能成像設備,它能夠對心腦血管疾病及腫瘤病變進行早期的無損診斷,在現代核醫學領域里起著十分重要的作用。分享友人