血吸蟲抗體 的英文怎麼說
中文拼音 [xiěxīchóngkàngtǐ]
血吸蟲抗體
英文
awa- 血 : 血名詞(血液 多用於口語) blood:吐血 spit (up) blood; 血的教訓 a lesson paid for [written] in b...
- 吸 : 動詞1 (把液體、氣體等引入體內) inhale; breathe in; draw 2 (吸收) absorb; suck up 3 (吸引) a...
- 蟲 : 名詞1. (蟲子) insect; worm 2. (姓氏) a surname
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 體 : 體構詞成分。
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Yherefore, many researchers have shown great concern with the development of vaccines to against schistosomiasis. at early stage, the research of vaccines of schitosomiasis was centered on dead vaccine and athenuated cercaria of schistosomes while molecular vaccine and athenuated cercaria of schistosomes while molecular vaccine is currently the focus of research with anti - infection protective immunity as its main concern. guan xiaohong and zhao weixian ( 1986 ) certified that the allergen of egg granulonma of schistosoma japonicum might firstly come from gut associated antigen ( gaa ) of schistosomula and adult worm and that daa had cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ) ; and the gaa of schistosoma japonicum might play a sensitizing role in egg granuloma formation
Np30主動免疫c57bl 6對尾蚴攻擊感染產生42 . 05的保護力,肝組織減卵率為66 . 63 ; balb c和昆明種小鼠的保護率分別為39 . 53和50 . 46 ;免疫山羊可誘導42 . 78的減蟲率,肝組織減卵率為35 . 83 ,糞減卵率為25 ,並可明顯抑制肝臟蟲卵肉芽腫的大小,肉芽腫數量明顯減少,纖維化減輕,體重明顯增加,因此np30是南京醫科大學博士學位論文很有希望的抗日本血吸蟲病疫苗侯選分子。Second, ca - np30 conjugate was made by binding ca with np30. then immunized balb / c mice with ca - np30, and evaluated its effects on protective immunity, serum specific igg antibody levels and delayed type hypersensitivity ( judged by footpad test )
將鈣納米顆粒ca與np30制備成ca皿30結合物( ca np30 ) ,主動免疫b從b兒, j 、鼠,觀察其對, j 、鼠抗血吸蟲感染的保護作用、對血清特異性屹g抗體的影響和足墊反應。Guan xiaohong ( 1991 ) established a cell line of the monoclonal anti - idiotypic antibody ( anti - id ) np30 of schistosoma - 6 - japonicum, whose isotype was identified to be igm and which was testified to be internal image of gaa
分別以日本血吸蟲單克隆抗獨特型抗體wbo的雜交瘤細胞株總基因組dna和其提取rna進行rticr合成的cdna第一鏈為模板,擴增v 。 、 v 。Guan et al ( 1991 ) established a strain of monoclonal anti - idiotypic antibody np30 ofschistosomajaponicum, which is an internal image anti - idiotypic antibody of gut associated antigen ( gaa ), its antibody isotype is igm. np30 has a partial cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ). np30 molecule has been researched on many aspects
管曉虹等( 1991 )建立了一株日本血吸蟲單克隆抗獨特型抗體np30 ,已證實為腸相關抗原( gaa )的內影像抗獨特型抗體,其抗體同型為igm ,與可溶性蟲卵抗原( sea )及膜相關抗原( maa )有部分交叉反應。Guan xiaohong, et al. ( 1991 ) established a strain of monoclonal anti - idiotypic antibody np30 of schistosoma japonicum, whice is an internal image antigen of gut associated antigen ( gaa ), its antibody isotype is igm. np30 has a partial cross - reaction with soluble egg antigen ( sba ) and membrane associated antigen ( maa )
管曉虹等建立的日本血吸蟲單克隆抗獨特型抗體( anti - id , ab _ 2 ) np30是腸相關抗原( gaa )的內影像anti - id ,與可溶性蟲卵抗原( sea )有交叉反應,可替代蟲源性抗原用於血吸蟲病免疫診斷和抗病疫苗的研究。The second part, a renewable piezoelectric immunosensor is developed for the antibody of schistosoma - japonicum ( sjab ). after incubating 32 kd molecular antigens of schistosoma japonicum ( sjag ) on the qcm by applying the immobilization above, the nonspecific sites on the immunosensor are sealed by using bsa and nrs together. the immunosensor can detect the sjab with the linear range of 0. 54 ~ 32. 50 ug / ml
以感染兔血清為檢測對象,採用聚電解質吸附固定法,將日本血吸蟲分子抗原( siag32kd )固定於石英晶振表面,再以牛血清白蛋白( bsa )和正常兔血清( nrs )聯合封閉晶振上非特異性活性位點,可在0 . 54 32 . 50ug ml范圍內檢測感染兔血清中日本血吸蟲抗體。So far, a lot of data from field sero - epidemiological investigations and laboratory studies have demonstrated that the schistosome specific ige antibody may play an important role in defense against the infection
大量的血清流行病學資料和實驗室研究的證據表明,血吸蟲特異性ige抗體在抗血吸蟲感染免疫中發揮重要作用。Using o - aminophenol as a substrate, hrp as label, a competitive immunoassay is used to determine the concentration of the analyte
幡的日本血吸蟲電化學免疫傳感器至少可用於100次日本血吸蟲抗體免疫分析。This thesis describes the preparation and " characterization of a renewable amperometric immunosensor based on sol - gel technology. renewable amperometric immunosensors have been developed for the complement 3 in human serum and schistosoma - japonium antibody, respectively. the detailed materials are showed as follows : this first part : renewable amperometric immunosensors have been developed with sol - gel as carrier
本論文報導了一種基於溶膠-凝膠技術的可更新的安培分析免疫傳感器的制備和特性,分別制備了用於人血清中補體第3成份的測定和日本血吸蟲抗體的測定。Thus, immunologists have sought smaller molecules with the antigen - recognition capability of antibodies. the variable domains of the heavy ( h ) and light ( l ) chains are sufficient for antigen recognition but the non - covalent complex of the two variable domains ( fv ) is unstable. it is possible to genetically engineer a single - chain fv ( scfv ) with the h chain v region connected to the l chain v region via a 15 amino acid linker composed of serine and glycine amino acid residues
二、日本血吸蟲單克隆杭獨特型抗體np30的單鏈狐( scf )的構建、表達及對balbic小鼠誘導保護性作用研究l 、日本血吸蟲單克隆杭獨特型抗體np0的單鏈抗體歸cfv )的構建、表達通過pcr方法體外擴增並經測序驗證的重鏈、輕鏈可變區( vh 、 vl )基因先後重組入原核表達質粒ptha90相應的位點上,中間通過一連接肽( gly在er ) 。When it ' s impossible to restrain schistosoma infection completely, a new way of controlling schistosomiasis is anti - pathology immunity, by mean of inoculating anti - pathology vaccine of schistosomiasis, could lessen the pathological damage of host as much as possible and improve the condition of organism
通過接種血吸蟲病抗病疫苗,減輕宿主的病理變化,改善機體狀態,以達到防治血吸蟲病的目的,成為另一條防治血吸蟲病的途徑,這一途徑已引起國內外專家的矚目。It has been confirmed that np30 has sensitizing effect on formation of hepatic egg granulomas in mouse model for hepatic egg granuloma of schistosoma japonicum ; immunization with np30 in kunming mice, c57bl / 6 mice and goats obtained worm reduction of 50. 46 %, 41. 67 % and 42. 78 %, respectively. np30 possesses effects of both anti - fecundity and anti - embryonation immunity on female worms of s. japonicum. moreover, np30 plays a significant down - modulatory role to hepatic granuloma and fibrosis ( the diameter, area and volume of egg granuloma were all significantly less than those of control ; the contents of type i, iii of collagen and fibronectin were also significantly less than those of control )
已對np30分子進行了較為廣泛的研究,應用小鼠日本血吸蟲肝肉芽腫模型證實np30對蟲卵肉芽腫的形成具有致敏作用;對感染宿主(昆明種小鼠、 c57bl / 6小鼠和山羊)具有較好的免疫保護作用(減蟲率分別為50 . 46 、 41 . 67和42 . 78 ) ;用np30主動免疫小鼠具有抗雌蟲生殖產卵和抗卵胚發育的雙重功效;另外,還對血吸蟲病肉芽腫和肝纖維化有明顯的負調節作用(蟲卵肉芽腫的直徑、面積和體積均明顯小於對照組,肝組織、型膠原及纖維連接蛋白含量均低於對照組) 。1 determine whether calcium nanopart i c i es can act as a vaccine adjuvant of anti - idiotypic antibody for schistosomiasis first, we prepared calcium nanaparticles ( ca ) by physical method, its diameter is 300 - 800 nm
1探索鈣納米顆粒ca作為血吸蟲病抗獨特型抗體疫苗佐劑的可行性應用物理方法制胸納米顆粒ca ;顆粒直徑為3o0一8o0m 。Application of dot immunogold filtration assayfor detecting serum antibodies in clonorchiasis patients
斑點金免疫滲濾法檢測華支睪吸蟲病患者血清抗體的研究Calcium nanoparticles as vaccine adjuvant of anti - idiotypic antibody for schistosomiasis 1
鈣納米顆粒作為血吸蟲病抗獨特型抗體疫苗佐劑的研究1This is important in attempting to use antibodies as anti - tumor reagents, for example
基因為日本血吸蟲單克隆抗獨特型抗體np30輕鏈和重鏈可變區基固。Anti - idiotypic antibody np30 was confirmed with protective immunity of both anti - infection and anti - pathology and may act as a vaccine candidate for schistosomiasis japonica
證南京醫科大學博士學位論文明抗獨特型抗體np30分子具有較好的抗感染免疫和抗病免疫功效,可作為日本血吸蟲病疫苗候選分子。Serum samples have been assayed and the results demonstrate feasibility of the proposed immunosensor for clinical analysis. ( 2 ) in chapter 2, a renewable amperometric immunosensor has been proposed for the determination of schistosoma - japonium antibody ( sjab ) in rabbit serum. the experimental conditions of sjab determination were studied and optimized
結果與臨床診斷用的elisa方法相比較,令人滿意八2 )在第二章中報導了制備可重復使用的日本血吸蟲電化學免疫傳感器,對r本血吸蟲抗體( sjab )的實驗條件進行了研究和優化。The sjab can be determined in the rang of 0. 32 - 19. 00 ng - ml " 1. ( 3 ) in chapter 3, we reported that the cyclic voltammetric behavior of l - o - allyl - 4 - hdroxy - anthraquinone ( oahaq ) in an aqueous medium and electrochemical characteristic of complex of oahaq and bsa. the complex reaction can be used to probe the interaction between these species and to electrochemical determine bsa
00ug 』 ml 」 』濃度范圍內對r本血吸蟲抗體進行了定量檢測3 )在第3章報導了在l o烯丙基4羥基蔥酮( oahaq )水溶液中加入bsa , omaq的循環伏安行為的變化情況,並可用來探測這些物種之間的相互作用關系以及用Amplification, cloning and sequence analysis of the light chain and the heavy variable region genes of monoclonal anti - idiotypic antibody np30 of schistosoma japonicum to amplify and sequence the gene of the heavy chain and the heavy chain of anti - idiotypic monoclonal antibody np30 of schistosoma japonicum
2 、日本血吸蟲單克隆抗獨特型抗體np30的單鏈抗體kcfv )對balb c小鼠誘導保護性作用研究為了研究日本血吸蟲抗獨特型抗體np30單鏈抗體作為日本血吸蟲病分享友人