裂解病毒 的英文怎麼說
中文拼音 [lièjiěbìngdú]
裂解病毒
英文
lytic virus-
The toxin may be formed within the pathogen and released when it dies ( endotoxin ), or secreted through its cell wall ( exotoxin )
在病原體內形成，當病原體裂解時被釋放的毒素為內毒素；由病原體通過細胞壁向外分泌的毒素為外毒素。If a drug could be made that inhibits this fragmentation process, it could substantially slow the spread of prions, which cause mad cow disease and scrapie in animals and, in rare cases, creutzfeldt - jacob disease and kuru in humans
藥物可阻滯這些蛋白裂解片段過程，從而持久的減慢朊病毒傳播，包括瘋牛病和綿羊瘋癢病和一些人類罕見疾病克-雅二氏病和庫魯病等疾病的傳播。After reproduction of the viral nucleic acid the host cell usually undergoes lysis ( lysogeny )
病毒核酸復制后寄主細胞通常要經歷裂解過程（溶源狀態） 。Viruses can give rise to two different types of phenomena: transformation and lytic infection.
病毒能產生兩類不同現象的轉化和裂解感染。Biological activity was determined by egf dependent balb / c 3t3 cell line and with mtt colorimetric assay. extracts of the recombinant virus - infected and mock - infected cells, haemolymph of the recombinant virus infected and mock - infected silkworm larvae could all support the proliferation of balb / c 3t3 cell. this phenomena implied that there were some egf - like growth factors in the haemolymph of normal silkworm larvae, which could enhance the proliferation of the cell line
用小鼠balb c3t3成纖維細胞和mtt法測定表達產物的促細胞增殖作用，發現重組病毒感染家蠶細胞72小時的胞內樣品與正常家蠶細胞裂解物，以及重組病毒感染4天的蠶血淋巴與正常蠶血淋巴均具有相似的促細胞增殖作用，甚至野生型病毒感染的細胞裂解物和蠶血淋巴也有一定的細胞促生長作用，提示家蠶系統本身可能含有能促進細胞生長、類似於egf的細胞因子。The protein product of meq gene was highly expressed in the nuclei of recombinant baculovirus infected sf9 cells when using an anti - meq monoclonal antibody ( mcab ) 23b46 to run the immunofluorescence assay ( fa ) ; the expression quantity and if staining patterns differed with different times post - infection ( pi ). the results of western blotting and immunoprecipitation test showed there were two specific bands around 60 kd. the results of the study demonstrated that the baculovirus / insect cell system is effective to be used to express nuclear protein of virus
結果發現:本表達系統產生的meq蛋白可被重組痘病毒表達的meq制備的單抗23b46所識別;在感染細胞中， meq蛋白僅局限於細胞核內，而且隨著感染后（ pi ）時間的增加，具有從核質向核仁和核膜轉移的趨向; w已stemblot和免疫沉澱試驗均證實重組桿狀病毒感染細胞裂解物中出現有兩條大小約為60kd的特異帶。The results indicate that the nucleotide sequences and deduced amino acid sequences of all the guangxi isolates in the signal peptides were highly homologous, but lowly homologous with other reference strains. the amino acid composes and arrangement of all guangxi isolates at the cleavage site has the typical pattern of ndv virulent strains, and is identical with the facts in the field cases. all the guangxi isolates are classified into genotype vii of apmv - 1, the same genotype dominated in china and other areas in recent years
結果發現，廣西分離株之間在信號肚的核旮酸和氨基酸同源性很高，而與其它參考株差異較大；廣西分離株在裂解位點的氨基酸組成和排列均符合強毒株的特徵，並與毒株在臨床上的致病情況相符；根據apmvlf基因第47位第420位核苦酸序列所繪制的系譜樹吵ylogenetictree ）來看，廠西雞和鵝分離株都歸屬于基因型vll 。The recombinant meq - baculovirus was obtained by co - transfecting the insect sf9 cells with pblubac4 - meq and linearised bac - n - blue dna. the recombinant baculovirus was selected by plaque assay and confirmed by pcr technique and sequencing of the inserted gene
應用重組痘病毒表達的meq制備的單抗23b46對重組桿狀病毒感染的sfg細胞及其裂解物分別進行間接免疫熒光試驗、 westemblot和免疫沉澱試驗的檢測。This strain ' s virulence was judged by mean death time of chick embryos ( mdt ), intracerebral pathogenicity index in day - old chicks ( icpi ) and intravenous pathogenicity index in 6 - week - old chickens ( ivpi ) and it was found to be the virulent strain. at last, it was tested by the recurrent infection and found that it was the newcastle disease virus ( ndv ), and it was named hbg - 1 strain. in order to find the difference of the cleavage site of this strain with f48e9 and ? 30 strain, a part of the cleavage site of fusion protein gene fragment was amplified by rt - pcr using a primer and sequenced. the sequence analysis showed this strain had low homology with f4ge9 and cso. a phylogenetic tree based on the published sequences of ndv reference strains was constructed and showed the isolated strain hbg - 1 belonged to the genotype w ndv, a novel genotype ndv
為了進一步探尋分離株與標準株的異同，又採用rt - pcr方法，擴增獲得分離株f _ o裂解位點附近的基因片段，經測序后與國際上已發表的新城疫病毒的核酸序列進行比較，結果表明其與標準株和疫苗株之間的同源性較低，僅為82 86之間。經系統發育進化樹分析后，判定該分離株為新城疫病毒（ ndv ）基因型。運用計算機軟體對其裂解位點處的氨基酸序列進行預測和分析，結果表明該分離株為新城疫病毒強毒株並具有基因型的典型結構特徵。A single protein plays a major role in deadly prion diseases by smashing up clusters of these infectious proteins, creating the " seeds " that allow fatal brain illnesses to quickly spread, new brown uniersity research shows
布朗大學最新研究顯示，有一種蛋白可能是朊毒病中關鍵蛋白，裂解感染性蛋白生成「種子」片段，然後侵襲腦組織致宿主迅速死亡。In addition, the amino acid residue at position 191 of receptor binding site ( rbs ) was his ( h ) in our five strains but that of others was asn ( n ) in our country
五株病毒的ha裂解位點均為parssr glf ，是典型的低致病性毒株；構成受體結合位點的191位氨基酸為his （ h ） ，國內其它毒株都為asn （ n ） 。Here, we provide a systems - oriented approach to interpreting the function of the dopamine system, its modulation of limbic - cortical interactions and how disruptions within this system might underlie the pathophysiology of schizophrenia and drug abuse
我們提供了一種系統的方法解釋說明多巴胺功能系統，它與邊緣葉皮質系統調制的交互作用，以及這一系統的破壞是如何引起精神分裂癥和吸毒成癮患者病理生理學改變的。But it is doubt that the speciality and stability for the outcome of detecting bdv orf i genome. we will detect the indviduals ' ( include the neuropsychiatric 4 patients with bdv orfii postive or not and healthy blood donator ) middle fragment of bdv orf i to help defmiting whether internal healthy people and the certain neuropsychiatric patient such as with viral encephalitis, multiple, schizophrenia, affective disorder have catch a bdv infection or not, most of all, the research is for understanding if there is any difference in the fragment from animal and human beings infected with bdv, thereby to find another sensitive and stably marker for confirming bdv infection, and establish a solide bottom for advanced study
但對另一編碼p40蛋白序列的檢測結果的特異性和穩定性還不肯定，我們通過對先前檢測bdvorf基因片段為陽性或陰性的神經精神病人和健康獻血者進行了bdvorf基因中部片段的檢測。以幫助確定在國內健康人群和某些神經精神疾病患者中如：病毒性腦炎、多發性硬化、精神分裂癥以及情感障礙等疾病中是否存在bdv的感染，更為重要的是了解感染人和動物的該病毒片段是否存在差異，從而找出另一檢測bdv感染的敏感性和穩定性的標記物，為下一步的研究奠定良好的基礎。分享友人