鈉通道 的英文怎麼說
中文拼音 [nàtōngdào]
鈉通道
英文
sodium cha el-
46da, respectively. the sequences of the two toxins are determined and found to consist of 34 and 36 amino acid residues, respectively. both of the two sequences include six cys residues, which form three disulphide bonds. jztx - can block neuromuscular transmission in an isolated mouse phrenic nerve diaphragm
Jztx -對電刺激誘導的小鼠膈神經-膈肌收縮產生抑制作用，濃度為1 . 0 10 ~ （ - 6 ） mol / l時的阻斷時間為15分鐘左右，對鈉通道和延遲調整型鉀通道的激活和失活沒有影響。So the results indicate that the two mutants have no significant difference in the toxicity of inhibiting mammal neuron sodium channels, and ala20 or ser20 was not the key residue. the two peptide neurontoxins inhibite mammalian voltage - gated sodium channels through a novel mechanism distinct from other known spider toxins such as 5 - actxs, - agatoxins i - vi which banded receptor site 3 to slow the inactive time course of sodium channels. we suggest that hntx - v maybe target the site 1 of sodium channels in a similar manner to - conotoxins and ttx
同時兩種海南捕鳥蛛毒素從影響ttx一s鈉通道的方式上來看，與其它已知膚類蜘蛛毒素如6一actxs等通過作用於位點3引起延緩鈉通道的失活時間存在明顯不同，我們推測hntx一iv和iintx一v可能是以一種新的不同於其它蜘蛛毒素的方式來影響鈉通道的，而ttx一s鈉通道位點1則很有可能便是它們的作用位點，與ttx和林一eonotoxins相似。Effect of atx on opening modes of myocyte sodium channel, action potential and qt intervals of ecg
海葵毒素對心肌鈉通道開放模式動作電位及心電圖In the presence of these chemicals or of temperatures above 43 degrees celsius, the channel allows sodium and calcium ions to flood into the nociceptor, stimulating it to generate a signal that translates into the burning sensation induced by heat, inflammation or spicy food
在這些化學物質存在下，或是體溫超過43 ，該離子通道就會讓鈉與鈣離子湧入痛覺受器；由此生成的訊息，則由腦部判讀成熱、發炎或辛辣食物所引起的燒灼感。Voltage sensitive na channels
電壓敏感性鈉離子通道This review will discuss the role of epithelial sodium channel ( enac ) and the cystic fibrosis transmembrane conductance regulator ( cftr ) in regulating the fluid volume and composition of the reproductive tract and their importance in various reproductive events such as sperm capacitation and implantation
本綜述著重探討了上皮細胞鈉離子通道和囊性纖維化跨膜電導調節體對雌性生殖道內液體容量和成分的調節以及它們在不同生殖事件，比如精子獲能及著床中的重要作用。The experimental results of the flow characteristics of the mmc heat sink indicate that the critical reynolds number signifying the transition from laminar flow to turbulent flow is in advance ; under the same experimental conditions, the variation in entrance direction of the microchannel inlet and outlet has little effect on the microchannel ; the experimental values of the friction factor of the de - ionized water in a microchannel agree well with those calculated using the theoretical laminar formula ; furthermore, a comparison of the experimental results and simulation results shows that navier - stokes equation and rng - turbulence model can be used to model the laminar and turbulence flow regions in a microchannel ; meanwhile, the correlations of the flow resistance in the turbulent flow regions for the de - ionized water as the working fluids are obtained from experiments
對歧管式單通道熱沉流動特性的研究結果表明，微通道內流體流態由層流向紊流轉變的臨界雷諾數提前;改變流體的進出口方向對熱沉總壓降造成的影響很小;摩擦系數的實驗值與理論值較接近;數值模擬結果能夠與實驗值較好吻合;並由實驗給出了紊流區流動阻力的實驗關聯式。此外，選用十二烷基硫酸鈉（ sodiumdodecylsulphate ， sds ）以及烷基多糖苷（ alkylpolyglycoside ， apg ）作為減阻添加劑，研究了表面活性劑添加對微通道流動特性的影響。Mutation screening of epithelial sodium channel gene in a
綜合征家繫上皮鈉通道基因突變的研究A study of mutation of the epithelial sodium channel gene in a
綜合征家系臨床和上皮細胞鈉通道基因突變的研究Sodium channel plays a major role in the resistance to synthetic pyrethroids in insects
鈉通道在昆蟲擬除蟲菊酯抗藥性中的重要作用Effects of droperidol on persistent sodium channel currents of pyramidal cell in hippocampal ca1 area of rats with cerebral ischemia
1區錐體細胞持續鈉通道電流的影響These anaesthetics block sodium channels and thereby the excitability of all neurons, not just sensory neurons
這些局麻劑可以阻斷鈉通道，因此不僅僅阻滯了感覺神經元，也同時阻滯了幾乎所有其他神經元的興奮性。These included mutations in the sodium channel gene scn5a, preiously associated with lqts and other unstable heart rhythm conditions and sudden death
這其中包括鈉通道基因scn5a的突變，該基因以前發現與lqts 、其他不穩定心律失常以及猝死相關。Most local anaesthetics used clinically are relatively hydrophobic molecules that gain access to their blocking site on the sodium channel by diffusing into or through the cell membrane
大多數應用於臨床的局麻藥物都是相對疏水性的分子，可彌散通過細胞膜，作用於阻滯部位的鈉通道。Unfortunately, the pharmaceutical industry has so far been unable to successfully develop selective inhibitors for such channels, in part because they closely resemble ttx - sensitive sodium channels, which appear widely throughout the nervous system
不幸的是，至今制藥界仍未成功研發出這種通道的選擇性抑制劑；部份原因是它與廣泛分佈於神經系統的ttx敏感型鈉通道十分近似。Sodium ion channel blocker in preventing the occurrence of chronic ache symptoms
鈉離子通道阻滯劑預防慢性疼痛癥狀發生的觀察After 50 nmol / l hntx - iv treatment for 5 min, the peptide didn " t effect the active and inactive time course of sodium currents and the steady - state activation of sodium channels, but it caused a 10. 1 mv hyperpolarizing shift in the voltage midpoint of steady - state sodium channel inactivation on drg neurons
細胞5分鐘后， ttx一s鈉電流的激活與失活相以及通道穩態激活特徵均無明顯改變，但ttx一s鈉通道能引起鈉通道的半穩態失活電壓有約10 . lmv的超極化漂移。 100二。Similar to hntx - iv, 100 nmol / l hntx - v did n ' t effect the active and inactive kinetics of currents and did n ' t have the effect on the active threshold of sodium channels and the voltage of peak inward currents. however, 100 nmol / l hntx - v caused a 7. 7 mv hyperpolarizing shift in the voltage midpoint of steady - state sodium channel inactivation
1 / liintx一v也不影響ttx一s鈉電流的激活相和失活相，對鈉通道的激活閩值和最大激活電壓也無明顯改變，但能引起鈉通道的半穩態失活電壓有7Resistance would be developed when the activities of any of these three enzymes are increased. the three insecticide target - sites are acetylcholinesterase ( ache ) for organophosphate and carbamate insecticides, voltage - gated sodium channels : knockdown resistance ( kdr or kdr - type ) for ddt & pyrethroids and y - aminobutyric acid ( gaba ) receptors for cyclodienes
殺蟲劑的作用靶標主要有：有機磷和氨基甲酸酯殺蟲劑的作用靶標?乙酰膽堿酯酶； ddt和擬除蟲菊酯類殺蟲劑的作用靶標?神經軸突鈉離子通道；環戊二烯類和吡唑類等殺蟲劑的作用靶標? -氨基丁酸（ gaba ）受體-氯離子通道復合體。Pain - sensing neurons, however, possess a subclass of voltage - gated sodium channels, known as the ttx - resistant type, that do not occur in the cns
不過，痛覺受器卻擁有一種特別的電位控制鈉離子通道，稱為河?毒（ ttx ）不敏感型，而中樞神經系統里並沒有這一型。分享友人