骨骼畸形 的英文怎麼說
中文拼音 [gǔgéjīxíng]
骨骼畸形
英文
skeletal deformity-
The protein nucleic acid complexes were identified by autoradiography for 48 h. the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2, with lonm tcdd and with both lonm tcdd and 1 jxm e2, individually ; the cat protein was examined by cat - els a. results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect. the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra, whereas the cell proliferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨骼致畸作用,骨骼發育畸形包括:內翻足、脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高( 10一15林擴kg ) ,致畸率明顯上升( 14 . 7 %一24 . 6 % ) ; tcdd和ra聯合用藥可以增強對大鼠骨骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用,對igfbp一6基因有負性調節作用, tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。The foot rectification implement can lighten the function obstacle of thenar skeleton and muscle system, and be used to correct and cure various illness of foot, such as the inflammation, deformity and instability of ankle joint and astragalus, as well as flatfoot, valgus, horse ' s hoof foot and pes arcuatus etc. besides disabled person, the foot illness of the old people especially the old women have become one kind of frequently - occurring and common disease along with the continuous improvement of people ' s life quality and the increasing aging of population in our country
足底矯形器的出現正是康復醫學發展的碩果之一。足底矯形器能減輕足底骨骼肌肉系統的功能障礙,用於矯治足部各種疾患,如踝關節和距骨下關節的炎癥、畸形、不穩定,以及扁平足、外翻足、馬蹄足、弓形足等。隨著我國人民生活質量的不斷提高和人口的日益老齡化,除殘疾人外,老年人特別是老年婦女的足部疾患已成為一種多發病和常見病。Classification and treatment of intramuscular vascular malformations of extremities
四肢骨骼肌血管畸形的分類與治療方法的研究The ere oligonucleotides were chemically synthesized, annealed, and labeled at the 5 " - ends by polynucleotide kinase and r - 32p atp ( 3000 ci / mmol ). for competed experiment the 400 fold molar excess of the cold ere oligonucleotides were added to reaction mixture
結論: 100一140m盯kg濃度的atra可以誘導大鼠骨骼畸形發育並產生ccf ; igfs家族基因中igf一2和igfbp一6表達的調控與大鼠骨骼發育以及成骨細胞的增殖密切相關。The laboratory animal studies on tcdd and ra exposure indicated high incidences of congenital developmental malformations. in our previously study, we analyzed gene expression profile in igf gene family of tcdd - and ra - reduced fetal rats as well as cells and found antiestrogenic effect of tcdd and ra on igf genes
我們應用ra對不同發育時期的胎鼠進行誘導,構建骨骼發育畸形大鼠動物模型,研究遺傳因素決定的先天畸形個體間對環境因素作用的易感性,闡明igfs家族成員在骨骼發育畸形大鼠中的作用。分享友人