agonist 中文意思是什麼

agonist 解釋
n. 名詞 【解剖學】主動肌。

  1. A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site.

    非競爭性拮抗劑可阻止激動劑在特定受體部位產生任何效應。
  2. This is most effective if a specific receptor blocking agent is available to counter the effects of a given agonist.

    在這方面最有效的是利用特效的受體阻滯藥對抗特定激劑的作用。
  3. Inverse agonist is a new type of classification

    摘要反向激動劑指一種新分類概念。
  4. Characteristics of inverse agonist action

    反向激動劑的藥理效應特徵
  5. Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4

    - arrestin2是趨化因子受體的一種重要的調節蛋白，本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用，反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制， cxcr4介導的趨化作用則被明顯抑制。
  6. Development of a functional reporter gene assay for the identification of glucagon - like peptide - 1 receptor agonist

    1受體激動劑功能性報告基因分析系統的構建
  7. Main methods and results are as followed : 1 epitope analysis of agonist - binding region of nrla physicochemical properties and antigenicity of two agonist - binding regions of nrla were analyzed through bioinformatics : domain p1 containing 151 amino acid residues preceding the first transmembrane domain of the human nrla, domain p2 with 144 residues following the third transmembrane domain. four parameters including hopp - woods and kyte hydrophilicityjanin accessibility, karplus - schulz flexibility, and welling antigenicity were used to determine the antigenic sites, and prosite programme and chou - fasman method were employed to analyze their related sequence motif and the secondary structures

    用goldkey軟體分別選取公認的hopp等與kyte等親水性參數、 jain表面可及性參數、 karplus - schulz主鏈柔韌性參數及welling抗原性參數對p1 、 p2兩個多肽片段進行參數分析。並採用通用的prosite程序與chou - fasman方法比較分析p1 、 p2多肽片段的氨基酸位點與二級結構特徵。綜合判定兩個多肽片段的抗原性及其位點，結果認為p2抗原性強于p1 。
  8. Pka agonist 8 - br - camp ( l0 # moi / l ) had no effect on lnmda and b ( 10 - ' momi ) suppression of nmda - evoked current

    即rp七amps也具有抑制inmda峰值和翻轉b對inmda快速抑制效應的作用。
  9. In these two studies by the same japanese group ( 7, 8 ), the enhanced pressor effects of ephedrine and phenylephrine following an alpha 2 agonist ( clonidine ) were no different between awake and anesthetized ( enflurane and nitrous oxide in oxygen ) patients

    在這兩個研究中[ 7 ， 8 ] ，麻黃素和苯腎上腺素在使用- 2受體激動劑（可樂定）后的升壓效果增強在清醒和麻醉（安氟醚和笑氣）病人沒有差別。
  10. Recently, some new studies suggest that small cytokine peptide - mimics can function as the agonist or antagonist of cytokine receptor, and these small molecular peptides can be synthesized easily and oral adminstration with high concentration. based on these work, we have tried to set up experiment on tnfa - binding peptides and tnfa mimotopes which may be as leads of tnfa antagonist

    近年來的研究發現，小分子細胞因子模擬物具有細胞因子受體激動劑或拮抗劑的作用，且小分子模擬物因容易合成並能夠給予高濃度、可口服等優點使其具有更加廣闊的研發與應用前景。
  11. Results of 31 case patients with newly diagnosed cardiac - valve regurgitation, 6 were currently exposed to pergolide, 6 were currently exposed to cabergoline, and 19 had not been exposed to any dopamine agonist within the previous year

    結果：有31例患者出現新診斷的心臟瓣膜返流，其中6例研究時正在服用培高利特， 6例使用卡麥角林，另外19例在研究的前一年中未再使用任何多巴胺受體激動劑。
  12. Similarly, xenopus spinal growth cones turned away from a gradient of baclofen, an agonist of the gabab receptor

    同樣的， gabab受體的激動劑baclofen的濃度梯度也能夠吸引或排斥爪蟾脊髓神經元的生長錐。
  13. In 1994, li et al isolated agmatine from cow brain. like clonidine, agmatine is an endogenous agonist at imidazoline receptors ( ir ) and a noncatecholamine ligand at ( ai - adrenergic receptors ( ( x2 - ar )

    胍丁胺（ agmatine ）是1994年li等從牛腦中分離純化的一種內源性可樂定置換物質（ clonidinedisplacingsubstance ， cds ） ，它可能作為一種新型的神經遞質或調質。
  14. A paper on controlling the illegal use of beta - agonist in pigs in hong kong is presented at the international symposium on safe pork in greece

    本署在希臘舉行的「安全食用豬肉國際研討會」上提交文件，介紹香港規管對豬只違法使用乙類速效劑的情況。
  15. To address this question, we investigated the effects of the ( - adrenergic agonist l - isoproterenol or antagonist dl - propranolol on in vivo ltp of area ca1 and spatial learning in morris water maze

    為此，我們觀察了-受體激動劑異丙腎上腺素（ isoproterenol ）或拮抗劑心得安（ propranolol ）對在體ca1區ltp的調控作用以及對大鼠在morris水迷宮中空間學習的影響。
  16. Recent investigation suggested that inverse agonist has potential clinical application

    反向激動劑有良好的臨床應用前景。
  17. Pulmonary function and intervention effects of 2 receptor agonist in patients with bronchial asthma

    2受體激動劑的干預效應
  18. It was found that plc activity was stimulated by both exogenous purified calmodulin and heterotrimeric g protein agonist cholera toxin. while, the stimulated effect on plc activity caused by exogenous calmodulin was inhibited by heterotrimeric g protein antagonist pertussis toxin, and plc antagonist u - 73122 inhibited the effect caused by cholera toxin. we also measure the free ca ~ ( 2 + ) level in germinating pollen grains, and found that exogenous purified calmodulin was able to increase the free ca ~ ( 2 + ) level, and their effects on ca ~ ( 2 + ) level were inhibited by u - 73122

    實驗中，利用[ ~ 3h ] pip _ 2和花粉原生質體共同孵育的體系，檢測出了百合花粉細胞具有依賴pip _ 2的plc活性；利用該體系還檢測出外源鈣調素可促進plc的活性，其中10 ~ （ - 9 ） m的鈣調素可使plc的活性提高三倍；異三聚體g蛋白的激活劑ctx可以激活plc的活性，而其抑制劑ptx可明顯抑制plc活性；外源鈣調素的這種作用可以被ptx抑制；而plc抑制劑u - 73122抑制ctx對plc的激活效應。
  19. Ephedrine and phenylephrine can treat the hypotension, howeer an amplified asoconstrictie response may be obsered due to an alpha 2 agonist induced enhancement of baroreceptor reflexes ( 7 ) and potentiation of alpha 1 - adrenoceptor - mediated asoconstriction

    麻黃素和苯腎上腺素可治療低血壓，然而可以觀察到存在過度縮血管反應，因為- 2受體激動劑導致壓力感受器反射[ 7 ]和- 1腎上腺素受體介導的血管收縮作用增強[ 8 ] 。
  20. The bioassay showed that the new compounds acted as inverse pure agonist on mvd and gpi and reversed by naloxone

    生物鑒定表明新化合物為可逆性阿片受體純激動劑並可被納絡酮完全對抗。
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