allogenic antigen 中文意思是什麼
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Objective the aim of this article was to induce long term survival allografts by blocking cd40 - cd40l pathway with homemade anti - cd40l monoclonal antibody mr1, then purify cd4 + cd25 + regulatory t cells from recipients with long term survival allografts, and adoptively cotransfer such cells together with tcr transgenic allogenic antigen specific cd8 + t cells into immunodeffient mouse. finally study whether cd4 + cd25 + t cells can suppress allogenic antigen specific cd8 + t cell mediated rejection, thus clarified whether cd4 + cd25 + t cell mediated regulation is one of mechanisms of prolongation of allograft survival by cd40 - - cd40l pathway blockade
從移植物長期存活的受體內分選出cd4 + cd25 + t細胞，與tcr轉基因cds + t細胞同時過繼輸注到免疫缺陷小鼠體內，觀察co4 + co25 + t細胞對同種異體反應性cos + t細胞介導排斥反應的作用，探討在阻斷cd40se一~ cd40l共刺激途徑延長移植物存活中， cd4 + cd25 +調節性丁細胞是否是抑制排斥反應的機制之一。
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