azalanstat 中文意思是什麼
azalanstat
解釋
阿扎蘭司他-
Inhibitors of cyp51, such as azalanstat ( rs - 2i607 ) and rs - 2i745, could inhibit the synthesis of ff - mas to decrease the accumulation of ff - mas. inhibitor of a14 - reductase, such as ay9944 - a - 7, could inhibit the metabolism of ff - mas to increase the accumulation of ff - mas ; and some other reagents, such as nystatin, could combine with the downstream intermediate in the cholesterol biosynthesis pathway to accumulate mas. in this study, we investigated the role of mas by using these reagents to change the level of endogenous ff - mas
抑制cyp51酶的抑制劑，如azalanstat （ rs - 21607 ）和rs - 21745等，均能抑制mas的合成，降低mas的積累；而抑制14 -還原酶的抑制劑，如ay9944 - a - 7等，能抑制ff - mas向t - mas的轉化而造成ff - mas的積累；還有一些物質，如制黴菌素，能阻止mas向下游的代謝而造成其積累，本文主要通過應用這些物質降低、或增加組織細胞中內源性mas的積累，來研究mas的作用。
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