caveolae 中文意思是什麼
caveolae
解釋
（復）小窩，小凹-
Disruption of lipid rafts and caveolae by depleting cellular cholesterol with cholesterol - binding reagent, - methylcyclodextrin or filipin, blocks the igf - 1 receptor signaling in 3t3 - l1 preadipocyte. both hormone induced adipocyte differentiation and mitotic clonal expansion are inhibited by lipid rafts and caveolae disruption. however, a nonspecific lipid binding reagent, xylazine, does not affect adipocyte differentiation or mitotic expansing
利用膽固醇結合試劑，如甲基環糊精和菲律賓菌素，減少細胞膽固醇的含量，破壞細胞膜上脂質筏/質膜微囊的結構，抑制了igf - 1受體信號誘導的3t3 - l1前脂肪細胞的分化以及克隆擴增。 -
Caveolae domains are found in most cell types, particularly in terminally differentiated cells. caveolin - 1, as the primary structural component ofcaveolae, plays a pivotal role in many signal transduction passways by regulating signaling molecules and participates in many physiologic processes, including apoptosis, angiogenesis, and sperm capacitation
小窩蛋白- 1在多條信號轉導通路中發揮著樞紐作用，通過調節這些信號轉導通路相關信號分子的活性，參與調節細胞凋亡、血管發生、精子發生以及精子獲能等生理過程。 -
Further studies indicate that lipid rafts and caveolae are required only for igf - 1 receptor downstream signaling and not the activation of receptor
而非特異性的脂質結合試劑， xylazine ，不影響脂肪細胞分化和克隆擴增。 -
Lipid rafts and caveolae are found to be essential for insulin - like growth factor ( igf ) - 1 receptor signaling during 3t3 - l1 preadipocyte differentiation induction. in 3t3 - l1 cells, igf - 1 receptor is located in lipid rafts and caveolae of the plasma membrane and can directly interact with caveolin - 1, the major protein component in caveolae
通過免疫熒光和純化脂質筏/質膜微囊的方法，發現igf - 1受體定位於脂質筏和質膜微囊中，而且igf - 1受體可以直接和微囊素1相互作用。
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