cell cycle checkpoint 中文意思是什麼

cell cycle checkpoint 解釋
細胞周期檢查點
  • cell : n 1 小室,單室;隔間,艙;〈詩〉茅舍;(單個的)蜂窩,蜂房。2 〈詩〉墓穴,墓。3 (大修道院附屬的...
  • cycle : n 1 循環,周期,一轉。2 周時,周年,年紀。3 (詩、故事等的)始末。4 自行車,三輪車,摩托車。5 【...
  • checkpoint : 復習要點
  1. These issues are essential to the understanding of the nature of cell cycle control, and to elucidating the roles of the histone acetylation modification in cell cycle regulation in eukaryotes. in this thesis, we studied the mechanisms of histone acetylation in cell cycle regulation in physarum polycephalum, a naturally synchronized slime mold. the results of this study confirmed that histone acetylation changed the expression of proteins related with the regulation of checkpoint conversion in cell cycle

    初步確定了組蛋白乙酰化在多頭絨泡菌細胞周期各轉換點的調控過程中對細胞周期調控相關蛋白表達水平的調節作用;了解了組蛋白乙酰化修飾對細胞周期各轉換點調控的作用途徑;建立了組蛋白乙酰化修飾對多頭絨泡菌細胞周期調控機制的基本模型。
  2. To investigate the functions of these factors, cells were treated with anti - c - fos, anti - c - jun and anti - ras antibodies and examined microscopically for the cell cycle progression. the results indicated that c - fos - like protein, c - jun - like protein and ras - like protein played important roles in checkpoint regulation in physarum polycephalum. western blot analysis showed that the c - fos - like protein and c - jun - like protein may act in cell cycle checkpoint by changing the cyclin b1 - like protein and p53 - like protein expression ; and the ras - like protein may act by changing the cyclin bl - like protein, p53 - like protein, c - fos - like protein and c - jun - like protein expression

    蛋白免疫印跡分析的結果表iv明,當s期、 gz期和前期細胞內具有功能活性的類ras蛋白的量減少時,細胞中的細胞周期調控因於類cyclinbi蛋白、類c jun蛋白、類c fos蛋白和類p53蛋白的表達水平,與未經抗體處理時相比發生了變化(或升高或下降) ;而山抗體處理引起的多頭絨泡菌細胞內具有功能活性的類c fos和類c jun蛋白的減少,使細胞內類cyclinbi蛋白和類p53蛋白的表達水平與抗體未處理時相比也發生了明顯的改變。
  3. Introduction protein kinase c ( pkc ) is a number of serine / threonine kinase family which play central regulatory roles in a multitude of cellular processes, including cell proliferation, cell cycle progression, differentiation, apoptosis. increasing evidence from studies using in vitro and in vivo systems suggests that pkc is a key regulator of critical cell cycle transitions, including cell cycle entry and exit and the gl and g2 checkpoint

    前言細胞周期是細胞增殖、分化的一個重要過程,它的啟動與進程受到嚴格調控,參與調控的因子不僅包含起正調控作用的細胞周期素( cyclins ) 、細胞周期蛋白依賴性激酶( cyclin - dependentkinase , cdk ) 、還有起負調控作用的cdk抑制因子( cyclin - dependentkinaseinhibitor , cki ) 。
  4. Cdk2 is an important member in cdks family, it directly participates regulation of g ^ s checkpoint and dna replication in s phase, its activity and functional regulation is one of the crucial key in cell cycle ' s operation, otherwise ; cdk2 has very close relation with cell canceration

    Cdk2是cdk家族中的重要成員,它直接參與細胞周期g _ 1 / s限制點( checkpoint )和s期dna復制的調節,它的活性和功能調節是細胞周期運轉的關鍵環節之一,與細胞癌變有著十分密切的關系。
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