cell growth inhibitor 中文意思是什麼
cell growth inhibitor
解釋
細胞生長抑制劑-
In addition to avermectins, s. avermitilis produces oligomycin, a strongly toxic compound. gene deletion vector pxl05 was used to disrupt oligomycin polyketide synthase ( pks ) encoding genes ( olma ) in streptomyces avermitilis cz8 - 73, the producer of anthelmintic avermectins b and the cell growth inhibitor oligomycin. olma gene cluster in the chromosome was displaced by deletion allele on the plasmid via double crossover
本研究以產阿維菌素b和寡黴素的阿維鏈黴菌cz8 - 73為出發菌株,構建了基因缺失載體pxl05 ,並將其轉入cz8 - 73中,通過缺失載體和染色體之間的同源雙交換,對染色體上長達90kb的寡黴素聚酮合酶( pks )基因簇( olma )進行了缺失。 -
Protein kinase a is camp - dependent kinase, one of the most important signal transduction pathways, plays a pivotal role in growth, differentiation, tumor occur, cell cycle control, etc. pka activators such as camp, 8 - br - camp or phosphodiesterase ( pde ) inhibitor isomethyl butyl xanthine ( imbx ) or purified pka catalytic subunit all can inhibit germinal vesicle breakdown ( gvbd ) and meiotic maturation in mouse oocytes, also in xenopus oocytes
蛋白激酶a ( proteinkinasea , pka )是依賴于camp的絲蘇氨酸蛋白激酶,是重要的信號傳導途徑之一,廣泛參與許多生命過程,包括生長、分化、腫瘤發生、細胞凋亡、細胞周期調控等。以小鼠卵母細胞為實驗對象,給予pka激動劑camp 、 8 - br - camp或磷酸二酯酶抑制劑imbx ( isomethylbutylxanthine )均可抑制小鼠卵母細胞的胚泡破裂及減數分裂成熟。
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