chromatin remodeling 中文意思是什麼

chromatin remodeling 解釋
(染色體重建):指發生在基因活化轉錄時核小體能量-依賴型的排列或重排。

  1. Epigenetic modification of the genome ensures proper gene activation during development and involves : genome methylation changes ; the assembly of histon and histone variants into nucleosomes and remodeling of other chromatin - associated proteins such as linker histones, polycomb group, nuclear scaffold protein, and transcription factors

    這些染色質的再程序化包括dna的甲基化和核小體組蛋白的乙酰化等。組蛋白乙酰化在染色質結構調節、 dna復制、基因轉錄、細胞分化及癌細胞發育都有研究,但在克隆動物中卻是一個有待深入探索的領域。
  2. The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation, such as zinc finger 198, 263, 14, 224, zf6, novel protein similar to transcriptional represser ctcf, and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction, cell - cycle control, chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions

    鑒定出的蛋白包括多個與轉錄調控相關的鋅指蛋白,如鋅指蛋白198 、 263 、 14 、 224 、 zf6 、轉錄抑制因子ctcf樣蛋白、幻肚pple樣鋅指蛋白等:兩個含金屬蛋白酶結構域和整合素結合結構域的家族成員adam28和adam17 ;兩個整合素家族成員pz整合素和含十個egf樣結構域的整合素( tied ) ;與細胞信號轉導通路有關的蛋白;與細胞周期調控有關的蛋白;與染色體重塑和基因轉錄抑制有關的蛋白;細胞骨架蛋白以及其他功能未明的蛋白等。
  3. The key to nuclear transplantation with adult cells lies in nuclear reprogramming or chromatin remodeling

    成年細胞核移植的關鍵在於核的再編序或核染質的再塑造。
  4. Human embryos do not provide enough time for chromatin remodeling, thus preventing the cloning of humans using adult cells

    人類胚胎沒有足夠長的時間進行核染質的再塑造,因而妨礙了用成人細胞克隆人類。
  5. Hbaf53 is a newly found subunit of a novel chromatin remodeling complex ? uman swi / snf complex

    Hbaf53是近年來在一個染色質改構復合物humanswi snf復合物中新發現的亞基。
  6. Brg1 is the catalytic subunit of the swi / snf chromatin remodeling complex and shows neural - enriched expression

    染色質重組裝復合物在轉錄中發揮重要的作用,參與了細胞增殖、分化和胚胎發育模式形成等過程。
  7. Human elongator complex serves a role in chromatin remodeling through modifying the lysine residues of histone h3 and h4 during transcription elongation in higher cells. the main results and conclusions are as followings. 1 using depletion strain of yeast as material, we have established a system for complementation test and gene expression analysis of human elongator complex

    4 、利用點突變和plasmidshuffle等技術構建了含h3k14一r 、 h4ks ~ r單突變和h3k14一側h4ks一r雙突變的e1p3乙菌株,通過功能互補實驗分析少凡p3對突變株的補償功能,證實酵母elongator可對h314k / h4sk進行乙酞化修飾。
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