conformational change 中文意思是什麼
conformational change
解釋
構象變化- conformational : adj. 構象的
- change : vt 1 改變，變更，變換，變革。2 交換；兌換；把（大票等）換成零錢；把（支票等）兌成現金。3 換（車、...
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Abstract : the effects of terbium ion on the conformation of calmodulin and on the interaction between calmodulin and melittin have been studied by the endogenous fluorescent spectrometry of calmodulin and melittin, and the sensitized fluorescent spectrometry of terbium ion, respectively. the results show that terbium ions have a tight binding site in the i and ii metal - binding sites of calmodulin. the conformation of calmodulin induced by terbium ion can bind melittin and transfer the tryptophane residue of melittin to a relatively hydrophobic environment, while the binding of melittin to calmodulin produces effect on the binding orders of terbium ion in camodulin. results from ft - ir spectrometry have revealed that upon binding of lanthanum ion, apo - calmodulin undergoes a conformational change with the increase of - helix content and the decrease of - sheet content. melittin ' s binding to calmodulin has no effect on its conformation induced by the binding of lanthanum ion to calmodulin
文摘:分別用鈣調蛋白和蜂毒素的內源熒光光譜以及鋱離子的敏化熒光光譜考察了鋱離子對鈣調蛋白構象變化以及對鈣調蛋白與蜂毒素相互作用的影響.結果表明，鋱離子首先結合在鈣調蛋白的第和第位點，鋱離子不影響鈣調蛋白與蜂毒素的相互作用，蜂毒素與鈣調蛋白作用后不影響鋱離子在鈣調蛋白上的鍵合順序.傅里葉變換紅外光譜結果表明三價的鑭離子與鈣調蛋白作用使鈣調蛋白的螺旋結構增加，折疊結構減少，與鈣離子對它的二級結構影響相類似.稀土離子在鈣調蛋白-蜂毒素復合體系中主要與鈣調蛋白作用 -
The small molecule causing the conformational change is an allosteric effector.
引起結構變化的小分子叫做變構效應場。 -
The results indicate that because of the improvement in two aspects mentioned above, the successful probability of the docking prediction is increased from unbound structures. for the case of enzyme trypsin - inhibitor appi, although the large conformational change occurs to the arg 15 side chain of appi upon complex formation, the native - like structure was still found and ranked first
其中，在胰蛋白酶appi復合物結構預測中，盡管抑制劑appi的15號殘基arg側鏈在復合物形成過程中發生了較大的構象變化，但其近天然結構仍然被找到了，並在打分中排在了第一位。
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