corl 中文意思是什麼
corl
解釋
科爾-
N - corl involving a corepressor complex ( including ncor, smrt, and hdac ) can mediate the transcriptional repression of thyroid horm
其人類的同源物可以與卜干擾素的啟動子, 1型免疫缺陷病毒重復長末端 -
To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei, and to study the function and mechanism of mint - mediated transcription repression, yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5, amino acids 2226 - 2959 ). from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo, fifty - one were positive for nutritional screening and p - galactosidase assay. restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments, which are mint, alpha a - crystallin - binding protein i ( alphaa - crybpl ), and nuclear receptor co - repressor 1 ( n - corl ), respectively
鑒于mwt基因編碼區較長,共有10799個堿基,故此我們將mint分為六段,分別命名為fi一f6 ,本研究以其中的f5 ( 222e959 )和f6 ( 296s576 )片段為研究對象,將h者分別插入pgb盯7載體中,結果顯示: mintfs可與核受體輔助抑制因子1階cori ) , o晶狀體蛋白結合蛋白1hlphatcrybp入及mw加互作用,而f6可與igm的重鏈恆定區、泛素結合酶2l6和一個未知功能的新的蛋白基因進行結合。 -
The results show that n - corl can also interact with another fragment f6 ( amino acids 2960 - 3576 ). further screening proteins that interact with anther fragment f6, we isolated the cdna of igm heaven chain contant region, ubiquitin - conjugating enzyme e2l6 and a new protein
Ddevempmentbiology6第四軍醫大學碩士研究生論文它可以和a晶體球蛋白基因的啟動子區結合而命名,后又發現其同源物可見于果蠅,線蟲,小鼠,大鼠以及人類等。
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