dimeric form 中文意思是什麼
dimeric form
解釋
二聚型-
The n - terminus truncated mutant can not form tight dimeric and tetrameric structure, and leads to the destruction of the quaternary structure, which is quite the contrary to wild type arog. these data indicate that n - terminus of arog is not only involved in the feedback inhibition, but also plays a role in the formation of stable dimer which is an essential structure for its enzymatic activity. according to the 3d structure, " d2 " symmetry of arog, to which contributed by leu 16, trp215 and his217, is essential for the feedback inhibition
對「 dz 」對稱性相關的氨基酸leul6 、 trpz15和hisz17進行點突變和雙突變研究結果表明: l ）在1mm苯丙氨酸的存在下， leul6ala 、 trpz15ala和hisz17ala能解除35一70 %的反饋抑制， t印2巧ala的比活降低65 %以上，其餘兩者的比活與野生型相近; 2 ）在lmm苯丙氨酸的存在下，導入雙點突變trpz1sai洲isz17ala和leul6hi撇isz17leu后能夠完全解除arog的反饋抑制，同時保持與野生型相當的比活。
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