dna damage response 中文意思是什麼

dna damage response 解釋
dna損害反應
  • dna : 1. deoxyribonucleic acid 【生物化學】去[脫]氧核糖核酸。2. deoxypentose-nucleic acid 去[脫]氧戊糖核酸。
  • damage : n 1 損害，損傷；〈口語〉傷害，毀壞。2 〈口語〉費用，代價。3 〈pl 〉 【法律】 賠償損失；賠償金。vt...
  • response : n. 1. 回答，答復。2. 【宗教】應唱聖歌。3. （因刺激等引起的）感應，反應，反響；應驗；【物理學】響應；【無線電】靈敏度，感擾性；特性曲線。
  1. Similarly, the cellular response to the environmental mutagens is not always initiated by dna damage

    同樣地，環境誘變劑誘發的細胞應答反應也不只是單純地由dna損傷所觸發的。
  2. The protein level of p21 increased lightly from 1 to3 h, then decreased at 6 - 9 h, reached maximum at 24 h after 2gy, it increased from 3 to 24 h exposed tology, and the protein level of p21 associated with cdk2 increased, which did not inhibit the cyclin e / cdk2 kinase activity, because of upregulation of cyclin e and deregulation of p27kipl after irradiation. in contrast to p21, p27kipl may be a key regulator of cyclin e / cdk2 activity in dna damage responses. hi the ubiquitin - proteasome pathway invovled in regulation of p27kiplexpression in response to ir the ubiquitin - proteasome pathway regulated selective and time - controlled elimination of p27 kipl

    與p27ki 」 ，表達水平不同， pzi蛋白表達水平在zgy照射后略有增加， 6一gh略有下降，在照后24h達到最大; 10gy照后1一3h開始增加，持續到24h ，並且cycline / cdkz復合物中pzi蛋白結合增多，但cycline / cdkz激酶活性並未受到抑制，除了因ir誘導cydine蛋白表達水平增加外，另一重要的原因就是與pzi同一家族的p27kip ，蛋白表達水平下降，失去了對cycline / cdkz的抑制活性。
  3. Though it has been researched for almost fifty years since discoveried in 1956, little has been known about the involvement of dna damage response pathways accounting for the radioresistance in this organism

    雖然對它的特殊抗性機制有近50年的研究歷史，但對于其中的分子機制仍知之甚少。
  4. Dna damage response

    Dna損害反應
  5. Our structure and function studies on ink, cdk4, and chk2 proteins shed great light on the mechanisms underlying some cancer diseases, while our enzymological characterizations of human and viral polymerases empower us to further understand the dna damage response and repair at dna level

    從相關的特殊功能蛋白質的性質和結構研究，到dna層次的酶學?定，我們已經建立了一套完整的體內和體外研究系統，並將利用蛋白質相互作用的特點，全力發展新一代生物藥物。
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