essential gene 中文意思是什麼
essential gene
解釋
（必須基因）：缺失會使生物致死的基因（見致死等位基因）。-
Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants
血吸蟲病疫苗研究已有60多年的歷史，大致經歷了死疫苗、活疫苗（照射致弱尾蚴疫苗）和基因工程疫苗等研究階段，產生了一些who / tdr推薦認為很有希望的疫苗候選分子，如谷胱甘肽- s -轉移酶（ gst ） 、副肌球蛋白（ sm97 ） 、照射致弱疫苗抗原5 （ irv - 5 ） 、磷酸丙糖異構酶（ tpi ） 、曼氏血吸蟲膜內在蛋白（ sm23 ）和脂肪酸結合蛋白（ fabp ， sm14 ）等，但其對宿主的保護作用均不甚理想，未能穩定地達到40或以上的保護力水平，因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑，進一步提高其保護力。 -
Relationships between angiotensin - converting enzyme gene polymorphism and lacunar infarction in early stage of essential hypertension
血管緊張素轉換酶基因多態性與高血壓病早期腔隙性腦梗死的關系 -
Pseudorabies virus ( prv ) is the causative agent of aujeszky ' s disease, which results in significant losses in pig husbandry. thymidine kinase ( tk ) gene is one of the main virulent genes of prv, and it is essential to the propagation of prv in the nerve tissues, but dispensable for virus replication and infection in other tissues
偽狂犬病是由偽狂犬病病毒（ pseudorabiesvirus ， prv ）引起的家畜和多種野生動物的一種以發熱、奇癢、呼吸和神經系統疾病為特徵的急性傳染病，妊娠母豬可發生死胎和流產，是危害養豬業的一個重要傳染病。 -
In escherichia coli, arog gene encodes phenylalanine - sensitive 3 - deoxy - d - arabino - heptulosonate - 7 - phosphate synthase isoenzyme arog that catalyzes the first committed step of shikimate pathway. here we study the essential amino acid residues involved in the formation of feedback inhibition site of arog, and the effects of n - terminus on feedback inhibition and its quaternary structure, and the importance of the structural " d2 " symmetry to allosteric inhibition
本博士論文工作以大腸桿菌k - 12來源的arog為研究對象，通過定點突變、反饋抑制實驗和酶學動力學參數的測定，深入地研究了arog的反饋抑制位點的特性，並對arog的n -末端在反饋抑制機理和維持穩定四級結構中的作用，以及蛋白質結構的「 d2 」對稱性對酶功能的重要性等進行了具體的研究。 -
It has been reported that the eiav s2 is not essential and does not appear to affect virus infection and replication in vitro. thus, we introduced a his - tag into the s2 gene of an eiav infectious molecular clone recombinant plasmid ( pok8266 ) by using soe pcr method and obtained a new recombinant plasmid with his - tag, designated as eiav - pok8. 2 - his
本研究應用已構建好的eiav驢白細胞弱毒疫苗株的感染性分子克隆載體（ pok8266 ）為模板，通過soepcr方法在感染性分子克隆載體的s2基因獨特區內引入突變點，形成含有酶切位點（ nspv ）的突變體（ p1p4 ） 。 -
Abstract : the polymorphism of angiotensinogen gene at position 174 was studied in 90 cases of essential hypertension patients and 109 controls by pcr, restriction enzyme analysis and electrophoresis methods. the results showed the distribution of genetypes in hypertension group was significantly different from that of controls group. this suggested there is a correlation between the variant of agt174 and hypertension
摘要本文採用pcr 、限制性酶切和電泳分型等方法，分別對90例原發性高血壓患者和109例正常人血管緊張素原基因多態位點agt174進行了檢測，結果表明，高血壓組中三種基因型的分佈與對照組顯著不同，提高該位點變異與原發性高血壓的發生相關。 -
With the acceleration of extinction of species, biodiversity conservation is extensively concerned. the extinction of species is concerned with the degree of threat by biotic and abiotic factors. so, taking action to preserve plant species is very necessary and paramount before their extinction. one of the most effective biological techniques to conserve the biodiversity is the establishment of genebanks, i. e. ex situ conservation. the elucidation of various factors that regulate seed viability and vigor in storage is essential. an ideal condition to prolong the longevity is mainly depended on seed water content, temperature, humidity and types of containers used during storage. the optimum stage of seed maturity, harvesting techniques and processing, in addition to physiological features such as degree of dormancy, also play key roles in seed storage. certainly, desiccated seeds deteriorate with time even under extremely good genebanking conditions. according to seed storage behavior, it is necessary to consider three principal factors : storage environment, storage duration and plant species which will affect seed survival under good genebanking conditions. the present review is an attempt to discuss the importance of the aforementioned aspects of seeds in detail in order to conserve plant germplasms ( especially wild rare and endangered plants ) for ex situ conservation through seed - gene bank
一個物種的滅絕是與其受生物因子和非生物因子的威脅程度相關的.隨著物種的加速絕滅，保護生物多樣性受到廣泛地關注.保護生物多樣性的最有效的生物技術之一是建立種子基因庫，進行遷地保護.種子庫理想的貯藏條件主要取決于種子含水量、貯藏環境（如溫度和濕度）和貯存種子的容器.進行種子貯藏，了解種子生命力和活力的影響因子的作用機理是十分重要和必要的.除了種子自身的生理特徵外，種子的貯藏壽命與種子成熟度、收獲技術、加工處理方法也是息息相關的.即使在最適的庫存條件下，種子也會隨時間發生劣變.因此，必須根據種子特定的貯藏行為，加以考慮影響種子存活的3個主要方面（貯藏環境、貯藏期和植物種類）而選擇有效的貯藏方案.本文試圖討論種子貯藏生理的幾個重要方面及其需解決的技術問題，以便更好地通過種子基因庫，長期有效地保存植物種質資源 -
They cannot naturally produce essential fatty acids - beneficial nutrients found mainly in plant and fish oil, so they must rely on a dietary supply. here we want to establish transgenic mice carry a tissue - specific expression gossypium hirsutum - 6 fatty acid desaturase ( fad2 ) gene which can add a double bond into an monosaturated fatty - acid hydrocarbon chain and convert oleic acid to linoleic
本試驗試圖構建一個肌肉組織特性的- 6脂肪酸去飽和酶（脫氫酶）真核表達載體，通過原核顯微注射法把棉花的- 6脂肪酸去飽和酶導入到小鼠體內，以小鼠為動物模型，建立動物體內的必需脂肪酸合成代謝通路。 -
( 2 ) deletions of four different lengths were conducted using pcr amplification with the information of sequence of pdf 1. 2 gene promoter. these mutated promoters were fused to the gus reporter gene and introduced into tobacco plants. the results of gus activity driven by these different constructs showed that the promoter sequence between positions - 300 and - 243 ( containing a gcc box and a g box - like sequence ) was an essential ja - responsive element region to activate the expression of gus reporter gene, and the - 300 bp position was defined as the boundary of the minimal functional promoter in response to ja signaling
（ 2 ）對該啟動子的5 』端進行不同長度的缺失突變，突變的啟動子與gus構建的融合基因在煙草中受meja誘導的瞬時表達結果表明，該啟動子中- 300 - 243bp區域（有一個gccbox和一個gbox - likesequence ）是其應答meja處理所必須的區域，並將- 300bp作為該啟動子應答ja信號的最小區域的邊界位置。 -
So it is response to the exogeneous hoemones at an early stage. hormones are essential for maintaining the expression of hrz, a ring zinc finger gene. hrz expresses in the explants cultured with hormones for 10 days and the level of expression is declined at day 15
因此， hzfj在外源激素的作用下，只在較短的時間內表達水平提高，表明該基因是對外源激素響應的早期基回c環狀鋅指蛋白基因hrz在未培養的外植體中表達。 -
Attachment to host tissue is essential for colonization by most mucosal pathogens, such as mycoplasma hyopneumoniae. according to the reported sequence of p97 gene in strain 168, a pair of primers was designed and the rl region of p97 gene in strain 168f485 was amplicated by pcr
本研究根據已報道的序列為參考，設計一對帶有ecor和hind酶切位點的引物，並通過引物的定點突變，利用pcr方法從豬肺炎支原體168f485株擴增到其黏附因子p97基因的抗原決定簇r1區。 -
Association of polymorphism of endothelial nitric oxide synthase gene with essential hypertension and its susceptivity to cerebral infarction
基因多態性與原發性高血壓及其腦梗塞易感性的關系 -
Upon the differentiation induction of 3t3 - l1 preadipocytes by hormone cocktail containing 1 - isobutyl - 3 - methylxanthine, dexamethasone and insulin, the preadipocytes undergo ~ 2 rounds of mitotic clonal expansion, which just precedes the adipogenic gene expression program and has been thought to be an essential early step for differentiation initiation
誘導分化的早期細胞會進行約兩輪的細胞分裂，被稱為克隆擴增。克隆擴增以前一直被認為可能有利於染色體的重構以易化分化所需要的基因表達，因此克隆擴增可能是3t3 l1前脂肪細胞分化所必需的過程。 -
Dna sequence analysis showed that the cloned nk gene was highly homologous to the sequence reported by nakamura. the deduced amino acid sequence also had the conserved sequences ( serine 221, histidine 64, and aspartic acid 32 ) which was essential for the catalytic center of serine proteases. the nk gene was then cloned into the transfer vector pvl1393
本實驗以b . subtilis （ natto ）基因組dna為模板擴增了nk基因，測序結果顯示與nakamura報道的納豆激酶基因高度同源，其氨基酸序列也含有絲氨酸蛋白酶的活性保守中心（ serine221 ， histidine64 ， asparticacid32 ） 。 -
So, as well as spelling out which amino acids are needed to produce a specific protein, the part of the exon immediately next to the intron contains information that is essential for the gene editing process
因此，我們除了要弄清楚哪些氨基酸是產生某一特定蛋白所必需的外，還要弄清楚緊靠內含子的外含子里哪一部分含有基因編輯過程所必需的信息。 -
Tpt1 is essential for the vegetative growth of s. cerevisiae and codes for the trna 2 ' - phosphotransferase by using the plasmid shuffling technique, we have constructed a tpt1 - deleted strain and transformed it with trpt1 gene and found that the trpt1 could complement the yeast tpt1
根據trpt1與模式生物酵母tpt1p的同源性，我們構建了tpt1的缺失菌株，利用plasmidshuffle技術，發現trpt1能夠互補酵母tpt1突變的功能，證明trpt1是tpt1的人類同源基因。 -
The promoter promoting the exogenous gene ' s transcription in the plant recipient is the essential condition that the exogenous gene can express
啟動子驅使外源基因在受體植株中啟動轉錄是外源基因能夠表達的必要條件。
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