ex vivo gene transfer 中文意思是什麼
ex vivo gene transfer
解釋
先體外后體內基因轉移-
3. using clamp technique, ex vivo gene transfer into liver graft was performed during cold preservation via perfusion of the portal vein with 5ml ringer ' s solution containing replication - defective adenovirus vector adhuctla4 - ig
供肝冷保存時,採用血管夾技術lamptechnique )經門靜脈灌注攜帶融合基因hllctla4dg的重組腺病毒,于術后3天、 7天能定性檢測到hllctla4ig在受體外劃血卜1 。 -
Using ex vivo gene transfer technique, exogenous gene was introduced to the liver graft during cold preservation and express locally in the graft. the effect of inhibition of rejection and inducing liver graft tolerance was observed. through this study, the possibility of achieving graft tolerance by gene transfer without routine immunosuppressive drugs was explored
我們採用adeasy腺病毒載體系統,自行構建攜帶huctla4 - ig的重組腺病毒,通過先體外后體內( exvivo )基因轉移技術,于供肝冷保存時,將該治療基因導入大鼠移植肝,使其于移植肝局部表達,觀察其抑制排斥反應,誘導大鼠移植肝免疫耐受的作用。
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