gene inactivation 中文意思是什麼

gene inactivation 解釋
基因失活
  1. In this study, the avermectin - producing strain streptomyces avermitilis was studied and the avermectin biosynthesis gene cluster in the genomic dna of streptomyces avermitilis s - 2 was altered by the method of gene engineering. insertion inactivation of aved gene in the cluster by introducing apramycin resistance gene into aved gene resulted in the disappearance of " a " components of avermectins. when avec gene was inactivated by the same way, four " 1 " components were lost and only " 2 " components, the potential precursor of ivermectin, were accumulated

    將該基因簇中的aved基因通過插入外源的安普黴素抗性基因片段使其失活,導致發酵產物中4個a組分(不需要的組分)的消失;將基因簇中的avec基因通過同樣手段,使其失活,導致發酵產物中4個「 1 」組分的消失,而主要積累「 2 」組分(進一步改造可成為伊維菌素的前體b _ 2組分) 。
  2. It was reported in the past decade that a targeted gene inactivation of some transcription factors could specifically affect the development of some groups of neurons in the brainstem and then resulted in distinct respiratory phenotypes

    近年來,人們利用分子生物學技術研究發現,小鼠某些基因突變可影響呼吸中樞特定神經元的發育,並由此導致特殊的呼吸表型。
  3. The gene silences the xi chromosome by spreading along the xi and inhibits most of its gene transcription. due to the important role it played in the inactivation process, xist is gradually becoming a hot spot.

    由於其在x染色體失活中的重要作用,對xist的研究一直是近幾年的研究熱點。其中很重要的一點就是試圖建立xist染色體在發育過程中的時空轉錄模式。
  4. Inactivation of genes which involved in signal transduction and analyze the phenotypes of mutants all the mutants in this study were inactivated by inserting a resistance gene

    信號轉導相關基因突變體的構建及表型分析本研究全部通過插入失活獲得突變體。
  5. Xist is an important gene wich is located in the xic ( x chromosome inactivation center ) region and is closely related to the x chromosome inactivation

    X染色體失活與位於「 x染色體失活中心」 ( xic )上xist基因息息相關,主要表現在xist的轉錄產物通過包圍一條x染色體使其沉默。
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