ghrelin 中文意思是什麼

ghrelin 解釋
饑惡激素
  1. K01458, 1284bp ), we designed the primers and regard the pcr productions as the internal standard. then by using rt - pcr analysis, high levels of expression of emu ghrelin mrna were detectable in proventriculus were detected, low levels of expression of duck ghrelin mrna were also detectable in lung muscle ileum duodenum corpus striatum cerebellum brain stem and gizzard

    K01458 ， 1284bp ）設計引物，以其pcr產物作為內標，分別以鴯鶓各個組織反轉錄產物為模板，通過多重pcr的檢測ghrelin的mrna在鴯鶓的各個組織中表達情況，結果發現ghrelin的mrna在鴯鶓ghrelin的mrna除在腺胃特異表達外，在肺、肌肉、回腸、十二指腸、紋狀體、小腦、腦干、肌胃也有少量表達。
  2. Ghrelin regulates pituitary growth hormone ( gh ) secretion. in the study, we obtained the cdna sequences of preproghrelin and the cdna encoding the ghrelin of duck, goose and emu by using rt - pcr and 3 " - race methods. and then deduced the amino acid sequences of preproghrelin and ghrelin in duck. goose and emu. sense and antisense primers were designed on the basis of chicken ghrelin cdna sequence ( dest accession no. ab075215, 836bp ) and proventriculus cdna was performed as the template

    Ab075215 ， 836bp ）設計引物，以鴨、鵝、鴯鶓腺胃cdna為模板，通過rt - pcr及3 - race的方法，將各個產物經過回收，再經連接轉化，克隆測序，拼接后得到鴨、鵝、鴯鶓preproghrelin基因的cdna序列及ghrelin的cdna序列，並由此推測出preproghrelin及ghrelin的氨基酸序列。
  3. Background : ghrelin is a 28 - amino acid endogenous peptide recently identified in the secretory granules of x / a - like cells in the rat stomach, which can act on the growth hormone secretagogue receptor to accelerate the secretion of growth hormone. it was identified that ghrelin - immunoreactive cell and its receptor localize in areas of brain, such as hypothalamus ( pvn, arc ), hippocampus, adenohypophysis and so on. motilin is a 22 - amino acid peptide secreted from the upper part of the small intestine, which regulates the interdigestive motility of gastric

    背景資料： ghrelin是新發現的由28個氨基酸組成的內源性腦腸肽，由胃部泌酸腺x / a樣內分泌細胞分泌， ghrelin免疫活性神經元及其受體在中樞神經系統中如下丘腦室旁核（ paraventricularneucleus ， pvn ） 、弓狀核（ arcuatenucleus ， arc ） 、海馬區及腺垂體等均有不同濃度的分佈，可與生長素促泌物受體（ growthhormonesecretagoguereceptor ， ghsr ）結合促進生長素（ growthhormone ， gh ）分泌。
  4. Van cauter ' s team found that when the 12 men in their study slept for four hours on two consecutive nights, their levels of leptin were 18 percent lower and their levels of ghrelin were 28 percent higher than they were after two nights of spending 10 hours in bed

    實驗發現，與連續兩晚睡足10個小時相比，連續兩晚只睡4小時的年輕男子，體內leptin的水平降低了18 % ，而ghrelin水平則上升了28 % 。
  5. Relationship between ghrelin and food intake or obesity

    與攝食和肥胖的關系
  6. Electrophysiological experiment : in 73 rats, extracellular recordings in vivo were made from pvn using 3 - barrel microelectrode. neurons were categorized as gastric distension excitatory ( gd - e ) or inhibitory ( gd - i ) neurons tested with gastric distension stimulus. drugs were applied through the 3 - barrel microelectrode by a 4 - programmable pressure injector ( pm2000b, mdi, usa ) : relin, saline ( control group ) relin, " [ d - lys - 3 ] - ghrp - 6 ( antagonist for ghrelin - r ), to observe the effects of drugs on the neuron discharge

    電生理實驗方法：在73隻大鼠中，應用三管玻璃微電極細胞外記錄麻醉大鼠一側pvn神經元自發放電，用水囊充盈胃鑒別胃擴張敏感神經元（ gdsn ） ，以壓力注射儀（ pm2000b ， mdi ， usa ）經三管玻璃微電極，對核團內中文摘要單個神經元分別微量注射給予: ghrelin 、生理鹽水ns （對照） ghrelin 、 d一lys一3 ]一ghrp一6 （ ghrelin受體拮抗劑） ，觀察藥物對神經元單位放電的影響。
  7. The researchers are still not certain whether the vaccine against ghrelin would prevent the development of obesity in humans who prefer a high - fat western style diet

    研究人員還不確定是否抗腦腸肽的疫苗能否阻止愛好西方高脂肪飲食習慣的人們體內的肥胖發展。
  8. Moreover, human ghrelin receptor exhibits a remarkable 50 % overall identity with human motilin receptor, therefore it was named as " raotilin - related peptide ". anatomical evidence showed that there are ascending and descending neuronal projections between pvn, bma and lower brain stem ( nts, dmx ), which participate in the regulation of gastric acid secretion and gastrointestinal motility. moreover, pvn is the center of appetite regulatory web

    Pvn與低位腦干（延髓迷走復合體）及邊緣系統之間有密切的纖維聯系，且含有多種神經肽，參與胃酸分泌，胃腸活動等多種生理機能的調節，是影響消化道功能與攝食行為的重要中樞部分， pvn內胃動素可促進胃排空和攝食，而新發現的ghrelin /胃動素相關肽是否參與此核區對胃運動的調節機制及其可能的神經通路尚不明了。
  9. The target of the vaccine is a hormone called ghrelin

    用疫苗的話，是一種稱為腦腸肽的激素。
  10. It was recognized as a brain - gut peptide since the peptide and its receptor exist in the central nervous system. previously, we demonstrated that motilin and motilides activates cells in paraventricular nuclei ( pvn ) reflected by increased gastric motility and induction of the immediate early gene c - fos in conscious rat, which suggests central motilin participates in the regulation of gastric motility. it was reported in 2001 that ghrelin is an appetite - stimu latory signal from stomach with structural resemblance to motilin

    胃動素（ motilin ， mt ）是由小腸上段粘膜內分泌細胞合成並分泌的22個氨基酸組成的腦腸肽，調節消化間期胃運動， pvn內給予胃動素和胃動內酯（ motilides ）可增強清醒大鼠胃運動，中樞微量注射胃動素可誘導pvn中立即早期基因c - fos的表達，提示中樞胃動素參與胃運動的調控，人ghrelin和胃動素之間有36的相似性，而且二者的受體之間有50的相似性，因而有人稱ghrelin為「胃動素相關肽」 。
  11. In the case of obesity vaccines, antibodies attach to the hunger protein called ghrelin, preventing it from reaching the brain and stimulating appetite

    在抑制過胖的疫苗方面，抗體會附著于名為饑餓激素的饑餓蛋白質上，防止它到達腦部刺激食慾。
  12. Object : to study the central effects of ghrelin on the activity of neurons in pvn and to investigate the involved neuronal pathway

    目的：研究ghrelin對大鼠下丘腦室旁核中胃運動相關神經元的作用，探討下丘腦ghrelin參與調控胃運動的機制。
  13. The two appetite - regulating hormones in question are leptin, which is released from fat cells and helps alert the brain that it ' s time to stop eating, and ghrelin, which is produced in the stomach and helps trigger hunger

    此項實驗中研究的兩種可以調節食慾的激素分別是「萊普汀」 leptin和「葛瑞林」 ghrelin 。
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